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831 research outcomes, page 1 of 84
  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Célia Caillet-Saguy; Nicolas Wolff;
    Publisher: HAL CCSD
    Country: France

    AbstractAngiotensin converting enzyme 2 (ACE2) is a main receptor for SARS-CoV-2 entry to the host cell. Indeed, the first step in viral entry is the binding of the viral trimeric spike protein to ACE2. Abundantly present in human epithelial cells of many organs, ACE2 i...

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  • publication . Preprint . Article . 2021
    English
    Authors:
    Nakamura, Gilberto M.; Plaszczynski, Stéphane; Grammaticos, Basile; Badoual, Mathilde;
    Publisher: HAL CCSD
    Country: France

    International audience; We study the effect of an emerging virus mutation on the evolution of an epidemic, inspired by the appearance of the delta variant of SARS-CoV-2. We show that if the new variant is markedly more infective than the existing ones the epidemic can r...

  • publication . Preprint . Article . 2020
    Open Access English
    Authors:
    Cédric Gil-Jardiné; Gabrielle Chenais; Catherine Pradeau; Eric Tentillier; Philipe Revel; Xavier Combes; Michel Galinski; Eric Tellier; Emmanuel Lagarde;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France

    Abstract Objectives During periods such as the COVID-19 crisis, there is a need for responsive public health surveillance indicators related to the epidemic and to preventative measures such as lockdown. The automatic classification of the content of calls to emergency ...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Andrew E. Clark; Conchita D'Ambrosio; Anthony Lepinteur;
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: France, Luxembourg

    We here use panel data from the COME-HERE survey to track income inequality during COVID-19 in France, Germany, Italy, and Spain. Relative inequality in equivalent household disposable income among individuals changed in a hump-shaped way between January 2020 and Januar...

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  • publication . Preprint . 2021
    Portuguese
    Authors:
    Soares de Cortes, João Paulo; Stoll, Émilie; Harayama, Rui;
    Publisher: HAL CCSD
    Country: France
  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Franziska Hufsky; Kevin Lamkiewicz; Alexandre Almeida; Abdel Aouacheria; Cecilia N. Arighi; Alex Bateman; Jan Baumbach; Niko Beerenwinkel; Christian Brandt; Marco Cacciabue; ...
    Publisher: HAL CCSD
    Countries: France, Belgium, Germany, Denmark, Belgium, France, Argentina, Switzerland, France
    Project: UKRI | Rfam: The community resou... (BB/S020462/1), EC | EpiPose (101003688), EC | REPO-TRIAL (777111), WT | University of Edinburgh -... (203783), UKRI | Bilateral NSF/BIO-BBSRC:A... (BB/N018354/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), UKRI | Capacity building for bio... (BB/P027849/1), EC | FeatureCloud (826078)

    SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly f...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Emmanuel Bonnet; oriane Bodson; Fréderic Le Marcis; Adama Faye; Emmanuel Sambieni; Florence Fournet; Florence Boyer; Abdourahmane Coulibaly; Kadidiatou Kadio; Fatoumata Binetou Diongue; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France

    Abstract Background: In early March 2020, the COVID-19 pandemic hit West Africa. Countries in the region quickly set up crisis management committees and organised drastic measures to stem the spread of the coronavirus. The objective of this article is to analyse the epi...

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  • publication . Preprint . 2020
    Open Access English
    Authors:
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jeremie Guedj; François Blanquart;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | PolyPath (844369), ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Abstract Repurposed drugs that are immediately available and have a good safety profile constitute a first line of defense against new viral infections. Despite a limited antiviral activity against SARS-CoV-2, several drugs serve as candidates for application, not only ...

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  • publication . Preprint . 2021
    English
    Authors:
    Maurel Ribes, Agnès; Bessière, Pierre; Guéry, Jean Charles; Joly Featherstone, Eloïse; Bruel, Timothée; Robinot, Remy; schwartz, olivier; Abravanel, Florence; Izopet, Jacques; Joly, Etienne;
    Publisher: HAL CCSD
    Country: France

    Serological tests are important for understanding the physiopathology and following the evolution of the Covid-19 pandemic. Assays based on flow cytometry (FACS) of tissue culture cells expressing the spike (S) protein of SARS-CoV-2 have repeatedly proven to perform sli...

  • publication . Preprint . 2021
    English
    Authors:
    Martin, Claude; Campéon, Arnaud; Le Bihan, Blanche; Legros, Michel;
    Publisher: HAL CCSD
    Country: France
831 research outcomes, page 1 of 84