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12 research outcomes, page 1 of 2
  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Touret, Franck; Gilles, Magali; Barral, Karine; Nougairède, Antoine; van Helden, Jacques; Decroly, Etienne; de Lamballerie, Xavier; Coutard, Bruno;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVA-GLOBAL (871029)

    International audience; A novel coronavirus, named SARS-CoV-2, emerged in 2019 in China and rapidly spread worldwide. As no approved therapeutics exists to treat COVID-19, the disease associated to SARS-Cov-2, there is an urgent need to propose molecules that could quic...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Guillaume Castel; Mathilde Couteaudier; Frank Sauvage; Jean-Baptiste Pons; Séverine Murri; Angelina Plyusnina; Dominique Pontier; Jean-François Cosson; Alexander Plyusnin; Philippe Marianneau; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: Finland, France
    Project: EC | ANTIGONE (278976), EC | EDENEXT (261504), ANR | ECOFECT (ANR-11-LABX-0048), ANR | Avenir L.S.E. (ANR-11-IDEX-0007)

    Puumala virus (PUUV) is the agent of nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) in Europe. NE incidence presents a high spatial variation throughout France, while the geographical distribution of the wild reservoir of PUUV, ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Yves Levy; Aurélie Wiedemann; Boris P. Hejblum; Mélany Durand; Cécile Lefebvre; Mathieu Surenaud; Christine Lacabaratz; Matthieu Perreau; Emile Foucat; Marie Dechenaud; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | CARE (101005077)

    The identification of patients with coronavirus disease 2019 and high risk of severe disease is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing gene expression analyses in severe hospitalized patients (n = 61). Relative to healthy do...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Muhammad Umar B. Niazi; Alain Y. Kibangou; Carlos Canudas-de-Wit; Denis Nikitin; Liudmila Tumash; Pierre-Alexandre Bliman;
    Persistent Identifiers
    Country: France
    Project: EC | Scale-FreeBack (694209)

    Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the disease transmission to suscep...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Vitaly Volpert; Malay Banerjee; Alberto d’Onofrio; Tomasz Lipniacki; Sergei Petrovskii; Viet Chi Tran;
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | FLUMODCONT (201601), EC | ASIAFLUCAP (201823), ANR | CADENCE (ANR-16-CE32-0007)

    International audience; In December 2019, the first case of infection with a new virus COVID-19 (SARS-CoV-2), named coronavirus, was reported in the city of Wuhan, China. At that time, almost nobody paid any attention to it. The new pathogen, however, fast proved to be ...

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  • publication . Article . 2021
    English
    Authors:
    Dimarco, Giacomo; Perthame, Benoît; Toscani, Giuseppe; Zanella, Mattia;
    Publisher: HAL CCSD
    Country: France
    Project: EC | ADORA (740623)

    International audience; Motivated by the COVID-19 pandemic, we introduce a mathematical description of the impact of sociality in the spread of infectious diseases by integrating an epidemiological dynamic with a kinetic modeling of population-based contacts. The kineti...

  • publication . Article . Conference object . 2020
    Open Access English
    Authors:
    Khan, Fahad; Romary, Laurent; Salgado, Ana; Bowers, Jack; Khemakhem, Mohamed; Tasovac, Toma;
    Publisher: Zenodo
    Country: France
    Project: EC | ELEXIS (731015)

    Due to COVID19 pandemic, the 12th edition is cancelled. The LREC 2020 Proceedings are available at http://www.lrec-conf.org/proceedings/lrec2020/index.html; International audience; In this article, we will introduce two of the new parts of the new multi-part version of ...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Tizzoni, Michele; Bajardi, Paolo; Decuyper, Adeline; Kon Kam King, Guillaume; Schneider, Christian M.; Blondel, Vincent; Smoreda, Zbigniew; González, Marta C.; Colizza, Vittoria;
    Publisher: HAL CCSD
    Countries: France, United States, Belgium
    Project: ANR | HarMS-flu (ANR-12-MONU-0018), EC | EPIFOR (204863)

    Human mobility is a key component of large-scale spatial-transmission models of infectious diseases. Correctly modeling and quantifying human mobility is critical for improving epidemic control, but may be hindered by data incompleteness or unavailability. Here we explo...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Andreas Dräger; Tomáš Helikar; Matteo Barberis; Marc R. Birtwistle; Laurence Calzone; Claudine Chaouiya; Jan Hasenauer; Jonathan R. Karr; Anna Niarakis; María Rodríguez Martínez; ...
    Publisher: Zenodo
    Country: France
    Project: EC | HELICAL (813545), NIH | A predictive multi-scale ... (5R35GM119770-02), EC | iPC (826121), EC | COSMIC (765158), NIH | Toward whole-cell models ... (5R35GM119771-02)

    Summary: Computational models of biological systems can exploit on a broad range of rapidly developing approaches, including novel experimental approaches, bioinformatics data analysis, emerging modelling paradigms, data standards, and algorithms. A discussion about the...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Romain Marlin; Véronique Godot; Sylvain Cardinaud; Mathilde Galhaut; Severin Coleon; Sandra Zurawski; Nathalie Dereuddre-Bosquet; Mariangela Cavarelli; Anne-Sophie Gallouet; Pauline Maisonnasse; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVAg (653316), ANR | IDMIT (ANR-11-INBS-0008), EC | TRANSVAC2 (730964)

    Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require additional approaches to currently approved viral vector and mRNA vaccines. Subunit vaccines may have distinct advantages when immunizing vulnerable individuals, children and pregnant wo...

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12 research outcomes, page 1 of 2