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844 Research products, page 1 of 85

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  • Publication . Preprint . Article . 2021 . Embargo End Date: 01 Jan 2021
    Open Access
    Authors: 
    de Vilmarest, Joseph; Goude, Yannig;
    Publisher: arXiv
    Country: France

    We present the winning strategy of an electricity demand forecasting competition. This competition was organized to design new forecasting methods for unstable periods such as the one starting in Spring 2020. We rely on state-space models to adapt standard statistical a...

  • Publication . Preprint . Article . 2021
    English
    Authors: 
    Nakamura, Gilberto M.; Plaszczynski, Stéphane; Grammaticos, Basile; Badoual, Mathilde;
    Publisher: HAL CCSD
    Country: France

    International audience; We study the effect of an emerging virus mutation on the evolution of an epidemic, inspired by the appearance of the delta variant of SARS-CoV-2. We show that if the new variant is markedly more infective than the existing ones the epidemic can r...

  • Publication . Preprint . Article . 2021
    Open Access
    Authors: 
    Célia Caillet-Saguy; Nicolas Wolff;
    Publisher: MDPI AG
    Country: France

    AbstractAngiotensin converting enzyme 2 (ACE2) is a main receptor for SARS-CoV-2 entry to the host cell. Indeed, the first step in viral entry is the binding of the viral trimeric spike protein to ACE2. Abundantly present in human epithelial cells of many organs, ACE2 i...

  • Open Access English
    Authors: 
    Cédric Gil-Jardiné; Gabrielle Chenais; Catherine Pradeau; Eric Tentillier; Philipe Revel; Xavier Combes; Michel Galinski; Eric Tellier; Emmanuel Lagarde;
    Country: France

    Abstract Objectives During periods such as the COVID-19 crisis, there is a need for responsive public health surveillance indicators related to the epidemic and to preventative measures such as lockdown. The automatic classification of the content of calls to emergency ...

  • Open Access English
    Authors: 
    Andrew E. Clark; Conchita D'Ambrosio; Anthony Lepinteur;
    Publisher: HAL CCSD
    Countries: Luxembourg, France

    We here use panel data from the COME-HERE survey to track income inequality during COVID-19 in France, Germany, Italy, and Spain. Relative inequality in equivalent household disposable income among individuals changed in a hump-shaped way between January 2020 and Januar...

  • Open Access English
    Authors: 
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jeremie Guedj; François Blanquart;
    Publisher: HAL CCSD
    Country: France
    Project: ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009), EC | PolyPath (844369)

    Abstract Repurposed drugs that are immediately available and have a good safety profile constitute a first line of defense against new viral infections. Despite a limited antiviral activity against SARS-CoV-2, several drugs serve as candidates for application, not only ...

  • Open Access English
    Authors: 
    Franziska Hufsky; Kevin Lamkiewicz; Alexandre Almeida; Abdel Aouacheria; Cecilia N. Arighi; Alex Bateman; Jan Baumbach; Niko Beerenwinkel; Christian Brandt; Marco Cacciabue; +45 more
    Countries: Germany, Belgium, France, France, Belgium, Denmark, Argentina, Switzerland
    Project: EC | FeatureCloud (826078), UKRI | Rfam: The community resou... (BB/S020462/1), UKRI | Capacity building for bio... (BB/P027849/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), UKRI | Bilateral NSF/BIO-BBSRC:A... (BB/N018354/1), WT | University of Edinburgh -... (203783), EC | EpiPose (101003688), EC | REPO-TRIAL (777111)

    SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly f...

  • English
    Authors: 
    Maurel Ribes, Agnès; Bessière, Pierre; Guéry, Jean Charles; Joly Featherstone, Eloïse; Bruel, Timothée; Robinot, Remy; schwartz, olivier; Abravanel, Florence; Izopet, Jacques; Joly, Etienne;
    Publisher: HAL CCSD
    Country: France

    Serological tests are important for understanding the physiopathology and following the evolution of the Covid-19 pandemic. Assays based on flow cytometry (FACS) of tissue culture cells expressing the spike (S) protein of SARS-CoV-2 have repeatedly proven to perform sli...

  • Open Access
    Authors: 
    Philippe Gautret; Jean-Christophe Lagier; Philippe Parola; Van Thuan Hoang; Line Meddeb; M. Mailhe; Barbara Doudier; Johan Courjon; Valérie Giordanengo; Vera Esteves Vieira; +8 more
    Publisher: Cold Spring Harbor Laboratory
    Country: France

    Background Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the role of hydroxychloroquine on respiratory viral loads. Patients and methods French Confirmed COVID-19 pa...

  • Open Access English
    Authors: 
    Bonnet, E.; Bodson, O.; Le Marcis, F.; Faye, A.; Sambieni, N. E.; Fournet, F.; Boyer, F.; Coulibaly, A.; Kadio, K.; Diongue, F. B.; +1 more
    Publisher: HAL CCSD
    Country: France

    Abstract Background: In early March 2020, the COVID-19 pandemic hit West Africa. Countries in the region quickly set up crisis management committees and organised drastic measures to stem the spread of the coronavirus. The objective of this article is to analyse the epi...