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- Publication . Other literature type . Conference object . 2016Open Access EnglishAuthors:Etienne Parizet; Ryan Robart; Perceval Pondrom; Jean-Christophe Chamard; Guillaume Baudet; David Quinn; Karl Janssens; Manfred Haider;Etienne Parizet; Ryan Robart; Perceval Pondrom; Jean-Christophe Chamard; Guillaume Baudet; David Quinn; Karl Janssens; Manfred Haider;Publisher: HAL CCSDCountry: FranceProject: EC | EVADER (285095)
International audience; Electric or hybrid vehicles are very silent, which represents a major advantage for the reduction of noise annoyance in urban areas. But this makes them dangerous for pedestrians, especially vulnerable ones as visually-impaired people. Current solutions consist in using warning sound so that the exterior noise of an electric vehicle is as high as for a conventional one. This may cancel the benefit of electric vehicles for the reduction of sound annoyance. The eVADER project (funded by the European Commission) aims at proposing a prototype car which combines a high safety and a low noise level. A part of the the work program consisted in perceptual studies. The goal of these studies was to evaluate the influence of various timbre parameters on the detectability and the unpleasantness of a warning sound. Results show that it is possible to make an electric vehicle easily detected while keeping its sound level much lower than the one of a conventional car.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Other literature type . Article . Conference object . 2004Open Access EnglishAuthors:Bernard Jouffrey; Peter Schattschneider; Cécile Hébert;Bernard Jouffrey; Peter Schattschneider; Cécile Hébert;
pmid: 15556701
Publisher: HAL CCSDCountries: France, SwitzerlandAbstract We resolve the long-standing mysterious discrepancy between the experimental magic angle in EELS— ∼ 2 ϑ E —and the quantum mechanical prediction of ∼ 4 ϑ E . A relativistic approach surpassing the usually applied kinematic correction yields a magic angle close to the experimental value. The reason is that the relativistic correction of the inelastic scattering cross section in anisotropic systems is significantly higher than in isotropic ones.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Preprint . Article . Conference object . 2018Open Access EnglishAuthors:Moser, Daniel; Abele, Hartmut; Bosina, Joachim; Fillunger, Harald; Soldner, Torsten; Wang, Xiangzun; Zmeskal, Johann; Konrad, Gertrud;Moser, Daniel; Abele, Hartmut; Bosina, Joachim; Fillunger, Harald; Soldner, Torsten; Wang, Xiangzun; Zmeskal, Johann; Konrad, Gertrud;Publisher: HAL CCSDCountry: FranceProject: FWF | Particles and Interaction... (W 1252)
The beta decay of the free neutron provides several probes to test the Standard Model of particle physics as well as to search for extensions thereof. Hence, multiple experiments investigating the decay have already been performed, are under way or are being prepared. These measure the mean lifetime, angular correlation coefficients or various spectra of the charged decay products (proton and electron). NoMoS, the Neutron decay prOducts MOmentum Spectrometer, presents a novel method of momentum spectroscopy: it utilizes the $R \times B$ drift effect to disperse charged particles dependent on their momentum in an uniformly curved magnetic field. This spectrometer is designed to precisely measure momentum spectra and angular correlation coefficients in free neutron beta decay to test the Standard Model and to search for new physics beyond. With NoMoS, we aim to measure inter alia the electron-antineutrino correlation coefficient $a$ and the Fierz interference term $b$ with an ultimate precision of $\Delta a/a < 0.3\%$ and $\Delta b < 10^{-3}$ respectively. In this paper, we present the measurement principles, discuss measurement uncertainties and systematics, and give a status update. Comment: 7 pages, 4 figures, accepted to the Proceedings of the International Workshop on Particle Physics at Neutron Sources PPNS 2018, Grenoble, France, May 24-26, 2018
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Part of book or chapter of book . 2013Open Access EnglishAuthors:Laurent Desvillettes; Klemens Fellner;Laurent Desvillettes; Klemens Fellner;Publisher: HAL CCSDCountry: FranceProject: ANR | KIBORD (ANR-13-BS01-0004)
International audience; We consider a prototypical nonlinear reaction-diffusion system arising in reversible chemistry. Based on recent existence results of global weak and classical solutions derived from entropy-decay related a-priori estimates and duality methods, we prove exponential convergence of these solutions towards equilibrium with explicit rates in all space dimensions.The key step of the proof establishes an entropy entropy-dissipation estimate, which relies only on natural a-priori estimates provided by mass-conservation laws and the decay of an entropy functional.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Conference object . 2014Closed Access EnglishAuthors:Mohammed Y. Boudjada; P. F. Biagi; Emad Al-Haddad; Patrick H. M. Galopeau; Bruno P. Besser; Daniel Wolbang; Gustav Prattes; H. U. Eichelberger; G. Stangl; Michel Parrot; +1 moreMohammed Y. Boudjada; P. F. Biagi; Emad Al-Haddad; Patrick H. M. Galopeau; Bruno P. Besser; Daniel Wolbang; Gustav Prattes; H. U. Eichelberger; G. Stangl; Michel Parrot; Konrad Schwingenschuh;Publisher: HAL CCSDCountry: France
International audience; We analyse the flux density variation associated to low frequency (LF) broadcasting transmitters observed by the ICE electric field experiment onboard DEMETER micro-satellite, observed from 01st Jan. to 09th Dec. 2010. We select five stations localised around the Mediterranean and the Black seas: Tipaza (252 kHz, 02°28’E, 36°33’N, Algeria), Roumoules (216 kHz, 06°08’E, 43°47’N, Monte Carlo), Polatli (180 kHz, 32°25’E, 39°45’N, Turkey), Nadour (171 kHz, 02°55’W, 35°02’N, Morocco) and Brasov (153 kHz, 25°36’E,45°40’, Romania). The detection of the LF transmitter signals by DEMETER micro-satellite is found to depend on the radiated power, the emitted frequency, and the orbit paths with regard to the location of the stations. This leads us to characterise the reception condition of the LF signals and to define time intervals where the detection probability is high. We show that LF signal are regularly recorded, each 12 days, when the satellite is above the broadcasting station. The signal intensity levels are principally significant during the solar activity. Hence we find that the solar and the geomagnetic activities are slightly correlated to the maxima of LF signal as recorded by DEMETER. Also we note a drop of the intensity level several days before the occurrence of earthquakes in/around the Mediterranean and Black seas.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Conference object . 2017Open Access EnglishAuthors:Alessandro Chiancone; Florence Forbes; Stéphane Girard;Alessandro Chiancone; Florence Forbes; Stéphane Girard;Publisher: HAL CCSDCountry: FranceProject: ANR | PERSYVAL-lab (ANR-11-LABX-0025)
International audience; Sliced Inverse Regression (SIR) has been extensively used to reduce the dimension of the predictor space before performing regression. SIR is originally a model free method but it has been shown to actually correspond to the maximum likelihood of an inverse regression model with Gaussian errors. This intrinsic Gaussianity of standard SIR may explain its high sensitivity to outliers as observed in a number of studies. To improve robustness, the inverse regression formulation of SIR is therefore extended to non-Gaussian errors with heavy-tailed distributions. Considering Student distributed errors it is shown that the inverse regression remains tractable via an Expectation- Maximization (EM) algorithm. The algorithm is outlined and tested in the presence of outliers, both in simulated and real data, showing improved results in comparison to a number of other existing approaches.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Conference object . 2017Closed Access EnglishAuthors:Mélissa Mary; Lina Fatima Soualmia; Xavier Gansel; Stéfan Jacques Darmoni; Daniel Karlsson; Stefan Schulz;Mélissa Mary; Lina Fatima Soualmia; Xavier Gansel; Stéfan Jacques Darmoni; Daniel Karlsson; Stefan Schulz;Publisher: HAL CCSDCountry: France
The emergence of electronic health records has highlighted the need for semantic standards for representation of observations in laboratory medicine. Two such standards are LOINC, with a focus on detailed encoding of lab tests, and SNOMED CT, which is more general, including the representation of qualitative and ordinal test results. In this paper we will discuss how lab observation entries can be represented using SNOMED CT. We use resources provided by the Regenstrief Institute and SNOMED International collaboration, which formalize LOINC terms as SNOMED CT post-coordinated expressions. We demonstrate the benefits brought by SNOMED CT to classify lab tests. We then propose a SNOMED CT based model for lab observation entries aligned with the BioTopLite2 (BTL2) upper level ontology. We provide examples showing how a model designed with no ontological foundation can produce misleading interpretations of inferred observation results. Our solution based on a BTL2 conformant formal interpretation of SNOMED CT concepts allows representing lab test without creating unintended models. We argue in favour of an ontologically explicit bridge between compositional clinical terminologies, in order to safely use their formal representations in intelligent systems.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Conference object . Part of book or chapter of book . 2004Open Access EnglishAuthors:Jakob Puchinger; Günther R. Raidl;Jakob Puchinger; Günther R. Raidl;Publisher: HAL CCSDCountry: FranceProject: FWF | Combining Memetic Algorit... (P 16263)
International audience; We consider the 3-stage two-dimensional bin packing problem , which occurs in real-world problems such as glass cutting. For it, we present a new integer linear programming formulation and a branch and price algorithm. Column generation is performed by applying either a greedy heuristic or an Evolutionary Algorithm (EA). Computational experiments show the benefits of the EA-based approach. The higher computational effort of the EA pays off in terms of better final solutions; furthermore more instances can be solved to provable optimality.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Conference object . 2008Closed Access EnglishAuthors:Bernard Klonjkowski; Dieter Klein; Sandra Galea; Francoise Gavard; Martine Monteil; Lidia Duarte; Annie Fournier; Sophie Sayon; Kamila Górna; Reinhard Ertl; +4 moreBernard Klonjkowski; Dieter Klein; Sandra Galea; Francoise Gavard; Martine Monteil; Lidia Duarte; Annie Fournier; Sophie Sayon; Kamila Górna; Reinhard Ertl; Nathalie Cordonnier; Pierre Sonigo; Marc Eloit; Jennifer Richardson;
pmid: 19070641
Publisher: HAL CCSDCountry: FranceInternational audience; The evaluation of vaccine strategies in animal models is essential for the development of a vaccine against HIV. In efficacy trials conducted in non-human primate models of AIDS, vaccines based on adenoviruses compared favourably with other vaccine vectors. To determine whether this strategy could be transposed to another animal model, and by extension, to humans, we have evaluated the efficacy of adenoviral vectors in a natural model of AIDS, infection of the cat by the feline immunodeficiency virus (FIV). Recombinant canine adenoviruses expressing the envelope glycoproteins or the Gag protein of a primary strain of FIV were constructed. Three groups of six cats were immunised twice with vectors expressing FIV antigens or with a vector expressing an irrelevant antigen, green fluorescent protein, by intramuscular and subcutaneous routes. Humoral responses were elicited against the transgene product in 6/6, 3/6 and 0/6 cats after immunisation against green fluorescent protein, Gag or the envelope glycoproteins, respectively. Six weeks after the second administration, cats were challenged by the intraperitoneal route with the homologous strain, and viral burden in plasma was followed by quantitative RT-PCR. Immunisation with FIV antigens did not afford protection. Rather, viral RNA was detected at earlier time points in cats immunised against Gag than in cats immunised with a vector expressing an irrelevant antigen. Such immune-mediated enhancement did not appear to have a long-range impact on viral set point or inversion of the CD4(+)/CD8(+) ratio. Thus, in the feline AIDS model pre-existing immunity against a viral antigen exacerbated acute phase infection.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Other literature type . Preprint . Conference object . 2005Open Access EnglishAuthors:Boris Adamczewski; Yann Bugeaud;Boris Adamczewski; Yann Bugeaud;Publisher: HAL CCSDCountry: FranceProject: FWF | Diophantine approximation... (M 822)
Let $\mathbf{k}$ be an arbitrary field. For any fixed badly approximable power series $\Theta$ in $\mathbf{k}((X^{-1}))$, we give an explicit construction of continuum many badly approximable power series $\Phi$ for which the pair $(\Theta, \Phi)$ satisfies the Littlewood conjecture. We further discuss the Littlewood conjecture for pairs of algebraic power series.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.
774 Research products, page 1 of 78
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- Publication . Other literature type . Conference object . 2016Open Access EnglishAuthors:Etienne Parizet; Ryan Robart; Perceval Pondrom; Jean-Christophe Chamard; Guillaume Baudet; David Quinn; Karl Janssens; Manfred Haider;Etienne Parizet; Ryan Robart; Perceval Pondrom; Jean-Christophe Chamard; Guillaume Baudet; David Quinn; Karl Janssens; Manfred Haider;Publisher: HAL CCSDCountry: FranceProject: EC | EVADER (285095)
International audience; Electric or hybrid vehicles are very silent, which represents a major advantage for the reduction of noise annoyance in urban areas. But this makes them dangerous for pedestrians, especially vulnerable ones as visually-impaired people. Current solutions consist in using warning sound so that the exterior noise of an electric vehicle is as high as for a conventional one. This may cancel the benefit of electric vehicles for the reduction of sound annoyance. The eVADER project (funded by the European Commission) aims at proposing a prototype car which combines a high safety and a low noise level. A part of the the work program consisted in perceptual studies. The goal of these studies was to evaluate the influence of various timbre parameters on the detectability and the unpleasantness of a warning sound. Results show that it is possible to make an electric vehicle easily detected while keeping its sound level much lower than the one of a conventional car.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Other literature type . Article . Conference object . 2004Open Access EnglishAuthors:Bernard Jouffrey; Peter Schattschneider; Cécile Hébert;Bernard Jouffrey; Peter Schattschneider; Cécile Hébert;
pmid: 15556701
Publisher: HAL CCSDCountries: France, SwitzerlandAbstract We resolve the long-standing mysterious discrepancy between the experimental magic angle in EELS— ∼ 2 ϑ E —and the quantum mechanical prediction of ∼ 4 ϑ E . A relativistic approach surpassing the usually applied kinematic correction yields a magic angle close to the experimental value. The reason is that the relativistic correction of the inelastic scattering cross section in anisotropic systems is significantly higher than in isotropic ones.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Preprint . Article . Conference object . 2018Open Access EnglishAuthors:Moser, Daniel; Abele, Hartmut; Bosina, Joachim; Fillunger, Harald; Soldner, Torsten; Wang, Xiangzun; Zmeskal, Johann; Konrad, Gertrud;Moser, Daniel; Abele, Hartmut; Bosina, Joachim; Fillunger, Harald; Soldner, Torsten; Wang, Xiangzun; Zmeskal, Johann; Konrad, Gertrud;Publisher: HAL CCSDCountry: FranceProject: FWF | Particles and Interaction... (W 1252)
The beta decay of the free neutron provides several probes to test the Standard Model of particle physics as well as to search for extensions thereof. Hence, multiple experiments investigating the decay have already been performed, are under way or are being prepared. These measure the mean lifetime, angular correlation coefficients or various spectra of the charged decay products (proton and electron). NoMoS, the Neutron decay prOducts MOmentum Spectrometer, presents a novel method of momentum spectroscopy: it utilizes the $R \times B$ drift effect to disperse charged particles dependent on their momentum in an uniformly curved magnetic field. This spectrometer is designed to precisely measure momentum spectra and angular correlation coefficients in free neutron beta decay to test the Standard Model and to search for new physics beyond. With NoMoS, we aim to measure inter alia the electron-antineutrino correlation coefficient $a$ and the Fierz interference term $b$ with an ultimate precision of $\Delta a/a < 0.3\%$ and $\Delta b < 10^{-3}$ respectively. In this paper, we present the measurement principles, discuss measurement uncertainties and systematics, and give a status update. Comment: 7 pages, 4 figures, accepted to the Proceedings of the International Workshop on Particle Physics at Neutron Sources PPNS 2018, Grenoble, France, May 24-26, 2018
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Part of book or chapter of book . 2013Open Access EnglishAuthors:Laurent Desvillettes; Klemens Fellner;Laurent Desvillettes; Klemens Fellner;Publisher: HAL CCSDCountry: FranceProject: ANR | KIBORD (ANR-13-BS01-0004)
International audience; We consider a prototypical nonlinear reaction-diffusion system arising in reversible chemistry. Based on recent existence results of global weak and classical solutions derived from entropy-decay related a-priori estimates and duality methods, we prove exponential convergence of these solutions towards equilibrium with explicit rates in all space dimensions.The key step of the proof establishes an entropy entropy-dissipation estimate, which relies only on natural a-priori estimates provided by mass-conservation laws and the decay of an entropy functional.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Conference object . 2014Closed Access EnglishAuthors:Mohammed Y. Boudjada; P. F. Biagi; Emad Al-Haddad; Patrick H. M. Galopeau; Bruno P. Besser; Daniel Wolbang; Gustav Prattes; H. U. Eichelberger; G. Stangl; Michel Parrot; +1 moreMohammed Y. Boudjada; P. F. Biagi; Emad Al-Haddad; Patrick H. M. Galopeau; Bruno P. Besser; Daniel Wolbang; Gustav Prattes; H. U. Eichelberger; G. Stangl; Michel Parrot; Konrad Schwingenschuh;Publisher: HAL CCSDCountry: France
International audience; We analyse the flux density variation associated to low frequency (LF) broadcasting transmitters observed by the ICE electric field experiment onboard DEMETER micro-satellite, observed from 01st Jan. to 09th Dec. 2010. We select five stations localised around the Mediterranean and the Black seas: Tipaza (252 kHz, 02°28’E, 36°33’N, Algeria), Roumoules (216 kHz, 06°08’E, 43°47’N, Monte Carlo), Polatli (180 kHz, 32°25’E, 39°45’N, Turkey), Nadour (171 kHz, 02°55’W, 35°02’N, Morocco) and Brasov (153 kHz, 25°36’E,45°40’, Romania). The detection of the LF transmitter signals by DEMETER micro-satellite is found to depend on the radiated power, the emitted frequency, and the orbit paths with regard to the location of the stations. This leads us to characterise the reception condition of the LF signals and to define time intervals where the detection probability is high. We show that LF signal are regularly recorded, each 12 days, when the satellite is above the broadcasting station. The signal intensity levels are principally significant during the solar activity. Hence we find that the solar and the geomagnetic activities are slightly correlated to the maxima of LF signal as recorded by DEMETER. Also we note a drop of the intensity level several days before the occurrence of earthquakes in/around the Mediterranean and Black seas.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Conference object . 2017Open Access EnglishAuthors:Alessandro Chiancone; Florence Forbes; Stéphane Girard;Alessandro Chiancone; Florence Forbes; Stéphane Girard;Publisher: HAL CCSDCountry: FranceProject: ANR | PERSYVAL-lab (ANR-11-LABX-0025)
International audience; Sliced Inverse Regression (SIR) has been extensively used to reduce the dimension of the predictor space before performing regression. SIR is originally a model free method but it has been shown to actually correspond to the maximum likelihood of an inverse regression model with Gaussian errors. This intrinsic Gaussianity of standard SIR may explain its high sensitivity to outliers as observed in a number of studies. To improve robustness, the inverse regression formulation of SIR is therefore extended to non-Gaussian errors with heavy-tailed distributions. Considering Student distributed errors it is shown that the inverse regression remains tractable via an Expectation- Maximization (EM) algorithm. The algorithm is outlined and tested in the presence of outliers, both in simulated and real data, showing improved results in comparison to a number of other existing approaches.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Conference object . 2017Closed Access EnglishAuthors:Mélissa Mary; Lina Fatima Soualmia; Xavier Gansel; Stéfan Jacques Darmoni; Daniel Karlsson; Stefan Schulz;Mélissa Mary; Lina Fatima Soualmia; Xavier Gansel; Stéfan Jacques Darmoni; Daniel Karlsson; Stefan Schulz;Publisher: HAL CCSDCountry: France
The emergence of electronic health records has highlighted the need for semantic standards for representation of observations in laboratory medicine. Two such standards are LOINC, with a focus on detailed encoding of lab tests, and SNOMED CT, which is more general, including the representation of qualitative and ordinal test results. In this paper we will discuss how lab observation entries can be represented using SNOMED CT. We use resources provided by the Regenstrief Institute and SNOMED International collaboration, which formalize LOINC terms as SNOMED CT post-coordinated expressions. We demonstrate the benefits brought by SNOMED CT to classify lab tests. We then propose a SNOMED CT based model for lab observation entries aligned with the BioTopLite2 (BTL2) upper level ontology. We provide examples showing how a model designed with no ontological foundation can produce misleading interpretations of inferred observation results. Our solution based on a BTL2 conformant formal interpretation of SNOMED CT concepts allows representing lab test without creating unintended models. We argue in favour of an ontologically explicit bridge between compositional clinical terminologies, in order to safely use their formal representations in intelligent systems.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Conference object . Part of book or chapter of book . 2004Open Access EnglishAuthors:Jakob Puchinger; Günther R. Raidl;Jakob Puchinger; Günther R. Raidl;Publisher: HAL CCSDCountry: FranceProject: FWF | Combining Memetic Algorit... (P 16263)
International audience; We consider the 3-stage two-dimensional bin packing problem , which occurs in real-world problems such as glass cutting. For it, we present a new integer linear programming formulation and a branch and price algorithm. Column generation is performed by applying either a greedy heuristic or an Evolutionary Algorithm (EA). Computational experiments show the benefits of the EA-based approach. The higher computational effort of the EA pays off in terms of better final solutions; furthermore more instances can be solved to provable optimality.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Conference object . 2008Closed Access EnglishAuthors:Bernard Klonjkowski; Dieter Klein; Sandra Galea; Francoise Gavard; Martine Monteil; Lidia Duarte; Annie Fournier; Sophie Sayon; Kamila Górna; Reinhard Ertl; +4 moreBernard Klonjkowski; Dieter Klein; Sandra Galea; Francoise Gavard; Martine Monteil; Lidia Duarte; Annie Fournier; Sophie Sayon; Kamila Górna; Reinhard Ertl; Nathalie Cordonnier; Pierre Sonigo; Marc Eloit; Jennifer Richardson;
pmid: 19070641
Publisher: HAL CCSDCountry: FranceInternational audience; The evaluation of vaccine strategies in animal models is essential for the development of a vaccine against HIV. In efficacy trials conducted in non-human primate models of AIDS, vaccines based on adenoviruses compared favourably with other vaccine vectors. To determine whether this strategy could be transposed to another animal model, and by extension, to humans, we have evaluated the efficacy of adenoviral vectors in a natural model of AIDS, infection of the cat by the feline immunodeficiency virus (FIV). Recombinant canine adenoviruses expressing the envelope glycoproteins or the Gag protein of a primary strain of FIV were constructed. Three groups of six cats were immunised twice with vectors expressing FIV antigens or with a vector expressing an irrelevant antigen, green fluorescent protein, by intramuscular and subcutaneous routes. Humoral responses were elicited against the transgene product in 6/6, 3/6 and 0/6 cats after immunisation against green fluorescent protein, Gag or the envelope glycoproteins, respectively. Six weeks after the second administration, cats were challenged by the intraperitoneal route with the homologous strain, and viral burden in plasma was followed by quantitative RT-PCR. Immunisation with FIV antigens did not afford protection. Rather, viral RNA was detected at earlier time points in cats immunised against Gag than in cats immunised with a vector expressing an irrelevant antigen. Such immune-mediated enhancement did not appear to have a long-range impact on viral set point or inversion of the CD4(+)/CD8(+) ratio. Thus, in the feline AIDS model pre-existing immunity against a viral antigen exacerbated acute phase infection.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product. - Publication . Article . Other literature type . Preprint . Conference object . 2005Open Access EnglishAuthors:Boris Adamczewski; Yann Bugeaud;Boris Adamczewski; Yann Bugeaud;Publisher: HAL CCSDCountry: FranceProject: FWF | Diophantine approximation... (M 822)
Let $\mathbf{k}$ be an arbitrary field. For any fixed badly approximable power series $\Theta$ in $\mathbf{k}((X^{-1}))$, we give an explicit construction of continuum many badly approximable power series $\Phi$ for which the pair $(\Theta, \Phi)$ satisfies the Littlewood conjecture. We further discuss the Littlewood conjecture for pairs of algebraic power series.
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.add Add to ORCIDPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.