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311 Research products, page 1 of 32

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  • Open Access
    Authors: 
    Nicola Salvi; Luiza Mamigonian Bessa; Serafima Guseva; Aldo R. Camacho-Zarco; Damien Maurin; Laura Mariño Perez; Anas Malki; Martin Hengesbach; Sophie Marianne Korn; Andreas Schlundt; +2 more
    Publisher: Springer Science and Business Media LLC
    Country: France
    Project: EC | AvINFLUENZA (796490)

    International audience; The non-structural protein nsp3 from SARS-CoV-2 plays an essential role in the viral replication transcription complex. Nsp3a constitutes the N-terminal domain of nsp3, comprising a ubiquitin-like folded domain and a disordered acidic chain. This...

  • Open Access English
    Authors: 
    Hugh Desmond;
    Publisher: Informa UK Limited
    Countries: France, Belgium
    Project: EC | EnTIRE (741782)

    Just as the COVID-19 pandemic has laid bare the limitations of medical codes of ethics (London 2021), it has also laid bare the limitations of scientific codes of ethics, particularly with regard t...

  • Open Access English
    Authors: 
    Aline Peltier; Valérie Ferrazzini; Andrea Di Muro; Philippe Kowalski; Nicolas Villeneuve; Nicole Richter; Oryaëlle Chevrel; Jean-Luc Froger; Alexis Hrysiewicz; Mathieu Gouhier; +19 more
    Countries: France, Germany
    Project: EC | EUROVOLC (731070)

    Abstract In March 2020, the coronavirus disease 2019 outbreak was declared a pandemic by the World Health Organization and became a global health crisis. Authorities worldwide implemented lockdowns to restrict travel and social exchanges in a global effort to counter th...

  • Open Access English
    Authors: 
    Peter Czuppon; Florence Débarre; Antonio Gonçalves; Olivier Tenaillon; Alan S. Perelson; Jeremie Guedj; François Blanquart;
    Publisher: HAL CCSD
    Country: France
    Project: EC | PolyPath (844369), ANR | TheraCoV (ANR-20-COVI-0018), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Abstract Repurposed drugs that are immediately available and have a good safety profile constitute a first line of defense against new viral infections. Despite a limited antiviral activity against SARS-CoV-2, several drugs serve as candidates for application, not only ...

  • Open Access English
    Authors: 
    Pierre Gallian; Boris Pastorino; Pascal Morel; Jacques Chiaroni; Laetitia Ninove; Xavier de Lamballerie;
    Country: France
    Project: EC | EVA-GLOBAL (871029)

    We investigated the distribution of antibodies neutralizing SARS-CoV-2 according to age, sex or blood group in French blood donors. In 464 samples collected before the emergence of SARS-CoV-2 (2017 and 2018), our virus neutralization assay had a 100% specificity. It was...

  • Closed Access English
    Authors: 
    Camille Lebarbenchon; Audrey Jaeger; Matthieu Bastien; Matthieu Le Corre; Koussay Dellagi; Hervé Pascalis;
    Publisher: HAL CCSD
    Country: France
    Project: EC | RUN-EMERGE (263958)

    International audience; We investigated circulation of coronaviruses, paramyxoviruses, and influenza A viruses in eight seabird species of the southwestern Indian Ocean. Viruses were not detected by real-time polymerase chain reactions in the 338 tested cloacal swab sam...

  • Open Access English
    Authors: 
    Michela Cozza; Silvia Gherardi; Valeria Graziano; Janet Johansson; Mathilde Mondon-Navazo; Annalisa Murgia; Kim Trogal;
    Publisher: HAL CCSD
    Countries: Italy, Sweden, France
    Project: EC | SHARE (715950)

    A lot of things need to be repaired and a lot of relationships are in need of a knowledgeable mending. Can we start to talk/write about them? This invitation - sent by one of the authors to the others - led us, as feminist women in academia, to join together in an exper...

  • Open Access English
    Authors: 
    Franziska Hufsky; Kevin Lamkiewicz; Alexandre Almeida; Abdel Aouacheria; Cecilia N. Arighi; Alex Bateman; Jan Baumbach; Niko Beerenwinkel; Christian Brandt; Marco Cacciabue; +45 more
    Publisher: Oxford University Press (OUP)
    Countries: France, Denmark, Germany, Switzerland, Argentina, France, Belgium, Belgium
    Project: WT | University of Edinburgh -... (203783), UKRI | Bilateral NSF/BIO-BBSRC:A... (BB/N018354/1), EC | REPO-TRIAL (777111), UKRI | Capacity building for bio... (BB/P027849/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), EC | FeatureCloud (826078), EC | EpiPose (101003688), UKRI | Rfam: The community resou... (BB/S020462/1)

    SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly f...

  • Open Access English
    Authors: 
    Eve Miguel; Véronique Chevalier; Gelagay Ayelet; Med Nadir Ben Bencheikh; Hiver Boussini; Daniel Kw Chu; Ikhlass El Berbri; Ouaffa Fassi-Fihri; Bernard Faye; Getnet Fekadu; +7 more
    Publisher: HAL CCSD
    Countries: China (People's Republic of), France

    Understanding Middle East respiratory syndrome coronavirus (MERS-CoV) transmission in dromedary camels is important, as they consitute a source of zoonotic infection to humans. To identify risk factors for MERS-CoV infection in camels bred in diverse conditions in Burki...

  • Open Access English
    Authors: 
    Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Nicolas eDegauque; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; Sophie eBrouard; +4 more
    Publisher: HAL CCSD
    Country: France
    Project: EC | VISICORT (602470), ANR | IGO (ANR-11-LABX-0016)

    International audience; Being able to track donor reactive T cells during the course of organ transplantation is a key to improve the graft survival, to prevent graft dysfunction, and to adapt the immunosuppressive regimen. The attempts of transplant immunologists have ...