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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Arıcı, İsmet; Korukçu, Abdurrrahim; Gündoğdu, Kemal Sulhi;
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Bursa Uludag Univers...arrow_drop_down
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Bursa Uludag Univers...arrow_drop_down
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Yeşildağ, Cemil;

    Bu çalışmada Ege Üniversitesi Tıp Fakültesi Göğüs Cerrahisi Anabilim Dalı’nda torakotomi geçiren hastalarda KPTA ağrı insidansının belirlenmesi amaçlandı. Ayrıca KPTA seyri, şiddeti, özellikleri, ağrının günlük yaşama etkisi ve analjezik kullanımı araştırıldı. Ege Üniversitesi Tıp Fakültesi Göğüs Cerrahisi Anabilim Dalı’nda Ocak 2007 ile Ekim 2009 tarihleri arasında torakotomi operasyonu geçiren 233 hasta incelendi. Birden fazla operasyon geçiren, ölüm nedeniyle kaybedilen, torakotomi dışında cerrahi girişim geçiren hastalar çalışmaya dahil edilmedi. Hastaların demografik verileri (yaş, cins, BMI), hastalık tanısı, geçirilen cerrahi girişim tipi, operasyon tarihi hasta dosyalarından elde edilen bilgiler eşliğinde kaydedildi. Çalışmaya dahil edilen tüm hastalar telefon ile arandı ve telefon ile ulaşılabilen hastalara geçirdikleri cerrahi işleme bağlı ağrı duyup duymadıkları soruldu. Torakotomiye bağlı ağrı duyduğunu bildiren hastalar görüşmeye çağırıldı ve ağrılarının değerlendirilmesinde Ağrı Sorgulama Formu (6) kullanıldı. Ege Üniversitesi Tıp Fakültesi Göğüs Cerrahisi Kliniği’nde torakotomi geçiren 233 hastadan 74 hasta çalışmaya dahil edilmedi: 27 hasta kaybedilmişti, 47 hasta birden fazla operasyon geçirmişti. 159 hasta çalışmaya dahil edildi ve telefon ile arandı. 47 hastaya ulaşılamadı, 112 hastaya telefon ile ulaşıldı. Yanıt alınabilen hasta oranı % 70.4 bulundu. Telefon ile görüşülen 112 hastadan 63 hasta geçirilen torakotomiye bağlı ağrı duyduğunu bildirdi, yanıt alınan hastalarda KPTA insidansı % 56 bulundu. Ağrı duyduğunu bildiren 63 hastadan 49 hasta görüşmeye geldi. 49 hastanın Ağrı Sorgulama Formu’na verdiği yanıtlara göre KPTA gelişen hastaların %69.4 kadarında ağrı şiddeti hafif, %26.5 kadarında ağrı şiddeti orta, %4.1 kadarında ise ağrı derecesi şiddetli bulundu. Bu hastalar içinde %89.7 hasta ağrısının zamanla azaldığını bildirdi. %38.7 hasta ağrısına yönelik analjezik kullanmakta idi, %24.4 hasta ağrının en kötü medikal problem olduğunu ve %24.4 hasta ağrının günlük aktivitesini kısıtladığını bildirdi. Nöropatik ağrı semptomlarının oranının %4 ile %61.2 arasında değiştiği görüldü. Sonuç olarak torakotomi geçiren hastalarda KPTA’nın %56 oranında görüldüğü, hastaların çoğunda ağrının hafif ve orta şiddette olduğu, %24 oranında günlük aktiviteyi kısıtlayabildiği görüldü. KPTA gelişimi, bu duruma neden olan periferik ve santral sinir sistemi değişikliklerini önleme konularında bilgilerimiz artıncaya kadar hastaların preoperatif olarak KPTA gelişme olasılığı ve sonuçları hakkında yeterli bilgilendirilmesi gerektiği kanısına varıldı.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ege University Insti...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ege University Insti...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Say, Bahar; Ergün, Ufuk; Yıldız, Ayşe; Alpua, Murat; +2 Authors

    Objectives: The aim of this study was to test the utility and validity of the full cup test (FCT) to assess the severity of pain in subjects with painful diabetic peripheral neuropathy (PDPN). Methods: Subjects with diabetic PDPN were enrolled for this prospective, cross-sectional study. Other causes of PDPN and subjects with cognitive impairment were excluded. The diagnosis of neuropathic pain was made using the results of a physical examination and the Douleur Neuropathique 4 questionnaire. Pain severity was assessed with a FCT and a visual analog scale (VAS) administered before and after treatment. The correlation of FCT with VAS was evaluated to examine validity. Results: A total of 43 (33 female, 10 male) subjects were included. The mean age was 61.9±8.25 years and the mean disease duration was 13.02±7.6 years. Type I diabetes mellitus (DM) was present in 2 (4.7%) subjects and Type II DM in 41 (95.3%) subjects. The mean glycated hemoglobin level was 8.9±1.9 mmol/mol. When the mean VAS and FCT scores were analyzed, the results were 6.7±2.05 and 66.35±23.2, respectively, pretreatment and 4.6±2.2 and 41.36±23.5 posttreatment, which were both statistically significant (p<0.001, p<0.001). The mean control period was 23.4 days (min–max: 15-30 days). The VAS and FCT scores in pretreatment and posttreatment demonstrated a high positive correlation (rs =0.86, p<0.001; rs =0.843, p<0.001). Conclusion: The FCT can be useful to detect pain severity in PDPN. Amaç: Dolu bardak testinin (DBT) ağrılı diyabetik periferal nöropati (ADPN)’de kullanımını ve geçerliliğini test etmek. Gereç ve Yöntem: Bu kesitsel ve prospektif çalışmaya ADPN olan olgular alındı. Çalışma popülasyonunda periferal nöropati yapacak diğer nedenler ve kognitif yetmezlik dışlandı. Periferik nöropati tanısı muayene ve Douleur Neuropathique 4 (DN4) anketi kullanılarak gösterildi. Ağrı şiddeti tedavi öncesi ve sonrasında DBT ve Vizüel Analog Skala (VAS) ile değerlendirildi. Geçerlilik için DBT’nin VAS ile korelasyonuna bakıldı. Bulgular: Çalışmaya 43 (33 kadın, 10 erkek) olgu alındı. Ortalama yaş 61.9±8.25, ortalama hastalık süresi 13.02±7.6 yıldı. Tip I DM 2 (%4.7) olguda, Tip II DM 41 (%95.3) olguda mevcuttu. HbA1c düzeyi ortalama 8.9±1.9 mmol/mol’du. Ağrı şiddetinin değerlendirilmesinde kullanılan VAS ve DBT tedavi öncesi ve sonrası karşılaştırıldığında ortalama skorlar tedavi öncesinde 6.7±2.05, 66.35±23.2, tedavi sonrasında ise 4.6±2.2, 41.36±23.5 bulundu. Sonuçlar istatistiksel olarak anlamlıydı (p<0.001, p<0.001). Olgularda ortalama kontrol süresi 23.4 (minimum–maksimum: 15–30) gün oldu. Ağrı şiddet ölçeği DBT, tedavi öncesi ve sonrasında VAS ile yüksek korele bulundu (rs =0.86, p<0.001; rs =0.843, p<0.001). Sonuç: Dolu bardak testi ADPN’de ağrı şiddetini belirlemede kullanışlı olabilir.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Kırıkkale Üniversite...arrow_drop_down
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Kırıkkale Üniversite...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Çavuşoğlu, Güneş Dorukhan;

    New biomarkers that will guide the diagnosis of rheumatoid arthritis are being studied and early diagnosis and treatment of the disease is aimed. Similar pathogenetic mechanisms of periodontitis and RA have been demonstrated. Disease activities of patients with RA who have periodontal disease tend to be worse. Previous studies suggest that calprotectin may be a valuable biomarker for the diagnosis and prognosis of RA. The relationship between calprotectin and disease activity in patients with periodontitis is known. In addition, several studies have shown that the salivary calprotectin level is high in patients with chronic periodontitis. A study showing the relationship between salivary calprotectin levels and disease activity in patients with RA has not been found in the literature so far. In this study, our aim is to evaluate the disease activity with serum and salivary calprotectin levels in patients with RA, and secondly, to evaluate periodontitis in these patients and to reveal whether serum and salivary calprotectin levels are related to periodontitis. 76 patients diagnosed with RA (Female/Male: 59/17) according to the 2010 ACR/EULAR classification criteria, 24 patients diagnosed with SS (F/M: 24/0) according to the 2016 ACR-EULAR classification criteria as the patient control group, and 40 healthy adults (F/M: 24/0) as healthy control group, who applied to the Medipol University Faculty of Medicine Rheumatology Department outpatient clinic, were included in the study. Demographic, clinical and laboratory data of the cases were recorded in the patient follow-up form, and periodontitis examination was performed after taking serum and saliva samples to measure the calprotectin levels simultaneously. Intergroup analyzes were evaluated with Student-T test and Mann-Whitney U test. The correlations between patient and physician-derived scales were evaluated with the Spearman correlation test. In patients with RA, serum calprotectin value was found to be higher in the group with high disease activity than in the group with low disease activity [HDA and LDA: 11.5 (0.78-38.23); 8.3 (1.6-24.4) (p:0.02)]. Mean serum calprotectin values were found to be higher in the RA group than in the other two groups, and there was a statistical difference between the RA group and the SS group, but no statistical difference was found between the RA group and the healthy control group [RA, SS, and HC, respectively: 13.6 (9.8); 8.1 (7.5) and 10.9 (6.02) (p:0.01)]. Median salivary calprotectin levels in patients with RA were found to be higher in patients with periodontitis than in patients without periodontitis [Periodontitis stage I and Periodontitis stage II-IV, respectively: 27.3 (1.6-40.74); 31.7 (0.64-75.85) (p:0.04)]. Serum calprotectin levels were found to be higher in the rheumatoid arthritis patient group than in the healthy and patient control group, and were correlated with disease activity. On the other hand, salivary calprotectin values in patients with rheumatoid arthritis were found to be lower than those of the healthy and patient control group. While periodontal inflammation was correlated with salivary calprotectin values in patients with rheumatoid arthritis, no such relationship was found in the other two groups. Similar to other studies, this study showed that serum calprotectin levels were positively correlated with disease activity markers. Romatoid artrit hastalığının tanısında yol gösterecek yeni biyobelirteçler üzerinde çalışılmakta ve hastalığın erken teşhisi ve tedavisi hedeflenmektedir. Periodontit ve RA'nın benzer patogenetik mekanizmaları gösterilmiştir. Periodontal hastalığı olan RA'lı hastaların hastalık aktiviteleri daha kötü seyretmektedir. Önceki çalışmalar kalprotektinin RA tanısı ve prognozu için değerli bir biyobelirteç olabileceğini göstermektedir. Periodontiti olan hastalarda kalprotektinle hastalık aktivitesi arasındaki ilişki bilinmektedir. Ayrıca kronik periodontiti olan hastalarda tükürük kalprotektin düzeyinin de yüksek olduğu birkaç çalışmada gösterilmiştir. RA tanılı hastalarda tükürükteki kalprotektin düzeyleriyle hastalık aktivitesinin ilişkisini gösteren bir çalışma şu ana dek literatürde bulunmamaktadır. Bu çalışmada amacımız RA tanılı hastalarda serum ve tükürük kalprotektin düzeyleriyle hastalık aktivitesini değerlendirmek, ikincil olarak da bu hastalarda periodontiti değerlendirerek serum ve tükürük kalprotektin düzeylerinin periodontitle ilişkisi olup olmadığını ortaya koymaktır. Medipol Üniversitesi Tıp Fakültesi Romatoloji Bilim Dalı polikliniğine başvuran, 2010 ACR/EULAR sınıflandırma kriterlerine göre RA tanısı almış 76 hasta (K/E: 59/17), hasta kontrol grubu olarak 2016 ACR-EULAR sınıflandırma kriterlerine göre Sjögren sendromu tanısı almış 24 hasta (K/E: 24/0) ve sağlıklı kontrol grubu olarak 40 yetişkin (K/E: 25/15) çalışmaya dahil edildi. Olguların demografik, klinik ve laboratuvar verileri hasta takip formuna kaydedildi ve eş zamanlı olarak kalprotektin için serum ve tükürük örneği alındıktan sonra periodontit muayenesi yapıldı. Gruplar arası analizler Student-T testi, Mann-Whitney U testi; hasta ve doktor kökenli ölçekler arası korelasyonlar Spearman korelasyon testiyle değerlendirildi. RA'lı hastalarda serum kalprotektin değeri, yüksek hastalık aktivitesi olan grupta, düşük hastalık aktivitesi olan gruba göre daha yüksek saptandı [YHA ve DHA: 11,5 (0,78-38,23); 8,3 (1,6-24,4) (p:0,02)]. Ortalama serum kalprotektin değerleri RA grubunda diğer iki gruba göre daha yüksek saptandı ve RA grubuyla SS grubu arasında istatistiksel fark saptanırken, RA grubu ile sağlıklı kontrol grubu arasında istatistiksel fark saptanmadı [RA, SS ve SK sırasıyla: 13,6 (9,8); 8,1 (7,5) ve 10,9 (6,02) (p:0,01)]. RA tanılı hastalarda ortanca tükürük kalprotektin düzeyleri, periodontiti olan hastalarda periodontiti olmayanlara göre daha yüksek saptandı [Periodontit evre I ve Periodontit evre II-IV sırasıyla: 27,3 (1,6-40,74); 31,7 (0,64-75,85) (p:0,04)]. Romatoid artrit hasta grubunda serum kalprotektin değerleri sağlıklı ve hasta kontrol grubuna göre yüksek saptanmış ve hastalık aktivitesiyle korele bulunmuştur. Buna karşılık romatoid artritli hastalarda tükürük kalprotektin değerleri sağlıklı ve hasta kontrol grubuna göre düşük saptanmıştır. Romatoid artritli hastalarda periodontal enflamasyon tükürük kalprotektin değerleri ile korele çıkarken, diğer iki grupta böyle bir ilişki saptanmamıştır. Bu çalışma diğer çalışmalara benzer şekilde serum kalprotektin düzeylerinin hastalık aktivite belirteçleriyle pozitif yönde korele olduğunu göstermiştir.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ İstanbul Medipol Uni...arrow_drop_down
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ İstanbul Medipol Uni...arrow_drop_down
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    Authors: Yıldırım, Mehmet;

    Bu yazıda, Yalazı/Balıkesir talk yatağından alınan cevher numunesinin zenginleştirme çalışmalarının sonuçları sunulmuştur. Manyetik mineral taşıyan serbestleşmiş tanecikler bir yüksek alan şiddetli yaş manyetik ayırıcı ile uzaklaştırılmıştır. Bu deneyde, demir içeriği bazında % 90,82 ayırma verimine ulaşılmıştır. Cevher içindeki manyetik olmayan yantaş mineralleri, doğal yüzebilirliği olan yaprağımsı talk mineral taneciklerinden flotasyon ile ayrılmışlardır. Bu çalışmalarla, % 6,99 demir içeren orijinal cevher numunesinden % 69,75 flotasyon verimi ile % 0,75 demir içeren bir talk konsantre elde edilebilmiştir. Son konsantrenin manyezit ve talk içerikleri termogravimetrik analizler ile belirlenmiştir. In this paper, results of the beneficiation studies of the ore sample taken from the Yalazı/Balıkesir talc deposit were reported. A high intensity wet magnetic separator discarded magnetic mineral bearing particles liberated. In this experiment, 90,82 % separation recovery based on the iron content was achieved. The non-magnetic gangue minerals in the ore were separated from the foliated talc minerals that are naturally floatable. A talc concentrate containing 0,75 % iron was obtained from the original ore sample containing 6,99 % iron with 69,75 % flotation recovery. Magnesite and talc contents of the final concentrate were determined by the thermogravimetric analysis.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Çukurova University ...arrow_drop_down
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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Yıldırım, İsmail;

    Keywords: Electric Arc Furnace, Oxygen Blowing. Nowadays, steel production with electric arc furnaces are gaining importance in Turkey and throughout the world. At present 40 % of the world's steel production are being produced by electric arc furnaces. Steel production with electric arc furnace has been brought about advantages such as high productivity, low production cost, easy raw materials handling and charging and simple production, high rate of energy saving, lower investment cost which have led to spread more easily. The aims of this study are to investigate and apply some of the recent developments in steel making technology with electric arc furnaces to improve the efficiency of 3 ton capacity model electric arc furnace, which is unefficient, without investing considerably to the plant for facilities in order to gain energy and raw materials savings. The developments which was applied to the model electric arc furnace include decarburizing by blowing oxygen to scrap charge and molten steel, scrap classification and scrap size reduction to increase the bulk density and decrease volume of scrap charge. Moreover, in order to reduce refractory consumption and optimize the refractory performance a chemical refractory binder MgS04.7H20 will be tried instead of using sodium silicate (known as glass water) as a binder. In this study, the second chapter describes the current situation and the importance of electirc arc furnaces in the steel industry, and also details of raw materials used, melting technique, principles of steel production, stages of steelmaking and finally the parts of electric arc furnaces were given. In the third chapter some of the recent developments in steel production with electric arc furnaces were introduced briefly.In the fourth chapter, the experimental results of decarburizing of molten steel by oxygen blowing and scrap classification and size reduction of scrap as a main charging material were given In the fifth chapter, an investigation into causes of refractory wear in 3 ton electric arc furnace were investigated and the problems were defined followed by the experimental results of refractory wear study, which occured in the model plant's electric arc furnace. Instead of using sodium silicate (known as glass water), MgS04.7H20 was used as a binder to improve and reduce the corrosion rate in the basic refractory lining of model electric arc furnaces. In this study, the economic effects of decarburizing of molten steel with oxygen blowing, scrap classification and scrap size reduction on the steel production cost and total steel production capacity were investigated. The steel production cost with oxygen blowing for decarburizing was found lower than that of decarburizing with iron ore addition. Also it increases the steel production capacity by 30 %. Only scrap classification and scrap size reduction increase steel production capacity around 20 %. The corrosion resistance of electric arc furnace refractory interior lining prepared using basic MgS04.7H20 binder was found improved compared to lining prepared with acidic silicate binder addition. Furthermore, the impact resistance of electric arc furnace lining prepared by the addition of sodium silicate were found better than lining prepared by MgS04.7H20 binder. xn Anahtar Kelimeler: Elektrik Ark Ocağı, Oksijen Üfleme Ülkemizde ve dünyada ark ocakları ile çelik üretimi gittikçe önem kazanmaktadır. Günümüzde dünya çelik üretiminin % 40'ı ark ocakları ile yapılmaktadır. Düşük ilk yatırım maliyeti, işlem maliyeti, kolay malzeme akışı, düşük maliyet, yüksek verimlilik ve enerji tasarrufu gibi etkenler ark ocakları ile çelik üretiminin yaygınlaşmasına neden olmuştur. Bu çalışmanın amacı, mevcut ark ocaklarının verimliliğini arttıran teknolojik gelişmelerden bazılarının örnek bir tesiste (1010 Ana Tamir Bakım Fabrikası Adapazarı) mevcut, verimli olarak çalışmayan 3 tonluk bir elektrik ark ocağında, önemli ölçüde ek bir yatırıma gitmeden tatbik edilmesiyle elde edilebilecek tasarrufların ve çelik üretim kapasitesinin nasıl artırılabileceğinin gösterilmesidir. Bu gelişmelerden deneysel olarak tatbik edilenler ; oksijen üfleme ile dekarbürüzasyon, hurda çeşitlerine göre sınıflandırma ve hurda boyutunu azaltarak şarj hacimini azaltma ve yoğunluğunu artırma, ayrıca normal olmayan refrakter tüketimini azaltmak için ocak astarlanmasında bağlayıcı olarak kullanılan cam suyu yerine MgS04.7H20 kullanılmasıdır. Bu çalışmada; 2. bölümde ark ocaklarının çelik üretiminde ki yeri, önemi yapısı, kullanılan hammaddeler, ergitme tekniği, çelik üretim prensibi, iş sırası, ve elektrik ark ocaklarının elemanların hakkında genel olarak bilgiler verilmiştir. 3. bölümde ise ark ocakları ile çelik üretiminde meydana gelen teknolojik gelişmelerden kısaca bahsedilmiştir. 4. bölümde teknolojik gelişmelerden oksijenle karbon giderilmesi, hurda tasnifi ve boyut küçültülmesi ile ilgili yapılan çalışmalara yer verilmiştir. 5. bölümde deneylerin yapıldığı örmek tesiste ki ark ocağında refrakter aşınması ile ilgili çalışmalar verilmiştir. Bu tezde oksijen üfleme ile dekarbürüzasyonun, hurda kesme ve sınıflandırmasının çelik üretim maliyetlerine ve çelik üretim kapasitesine etkileri ekonomik olarak değerlendirilmiş olup sadece hurda kesme ve sınıflandırma ile % 20 kapasite artışı gözlenmiştir. Çelik üretim maliyetlerinin ise demir cevheri ile kaynatmayla kıyasla oksijenle dekarbürüzasyonla azaldığını ve çelik üretim kapasitesini önce ki duruma göre % 30 artırdığı tespit edilmiştir. Ayrıca ocak astar malzemesinde bağlayıcı olarak kullanılan asidik cam suyu yerine bazik karakterde MgS04.7H20 kullanımı ile astarın cürufa ve sıvı çeliğe karşı korozyon direncinin cam suyuna göre daha iyi olduğu, bunun yanında MgS04.7H20 kullanarak yapılan astarların darbe mukavemetlerinin cam suyu ilavesi ile hazırlanan astarlara göre daha düşük olduğu yapılan denemeler sonucunda belirlenmiştir. XI Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır.

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    Authors: Afşin, Mustafa; Elhatip, Hatim;

    Tuzlusu thermal-mineral springs emerge at the intersection of faults, parallel to the Tuzgölü fault zone and oblique to these faults in NW of Aksaray. The marbles of the Bozçaldağ metamorphics, cropping out at Çal region and its vicinity, form the main aquifer of these springs. The total discharge of the springs is low, while their CO2 and total dissolved solids (TDS) contents are high. In addition to the old travertines extending along the main faultline, recent travertine depositions exist in places where thermal-mineral water appears. The travertine in this region is formed under certain conditions including low flow depth, turbulent flow, and increasing pH and temperature values due to the loss of CO2 Evaluation of 18O, 2H, 3H isotopic data indicates the meteoric origin of the Tuzlusu springs. The temperature of the springs decreases after leaching the granites and evaporites on their circulation paths. The results of 13C analysis show that a part of CO2 of the water is of marine carbonate origin. The hydrochemical fades of the Tuzlusu springwaters are in Na-Ca-CI-HCO3 and Na-CI types, and the temperature of the reservoir rock is around 115°C. Total hardness and salinity hazard potential of the springs are high, and hence they could not be used for irrigation purposes. Tuzlusu sıcak ve mineralli su kaynakları, Aksaray'ın KB'sında Tuzgölü fay zonuna paralel ve buna verev fayların kesişme noktalarında yer alırlar. Kaynakların akiferini oluşturan Bozçaldağ metamorfitlerine ait mermerlerin bir bölümü Çal mevkiinde yüzeylenmektedir. Kaynak sularının toplam debisi düşük, CO2 ve toplam çözünmüş madde (TDS) miktarları ise yüksektir. Tuzlusu kaynak alanında ana fay boyunca yer alan eski travertenlerin yanısıra, sıcak ve mineralli suların aktığı yerlerde yeni traverten çökelimleri devam etmektedir. Traverten çökeliminde kanaldaki su kalınlığının az olmasının yanısıra, türbülan akım, CO2 gazı kaybı, pH ve sıcaklığın yüksek olmasının da önemli rolü vardır. 18O, 2H, 3H izotop verilerine göre meteorik kökenli olan Tuzlusu kaynakları, dolaşım yolu boyunca sokulum yapan granitleri ve evaporitli birimleri yıkayarak yeryüzüne ulaşmış ve sıcaklığını bir miktar kaybetmiş olabilir. 13C analiz sonuçlarına göre ise, kaynak sularındaki karbondioksitin bir bölümü denizel karbonat kökenlidir. Na-Ca-CI-HCO3 ve Na-Cl tipi su kimyası fasiyeslerine giren kaynak sularının hazne kaya sıcaklığı 115°C dolayındadır. Sertliği ve tuzluluk tehlikesi çok yüksek olan bu suların sulama suyu olarak kullanılması uygun değildir.

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    Authors: Belkıs Ünsal; A. Ömer Özütemiz; Murat Alkanat; Kadir Aksöz; +2 Authors

    In inflammatory bowel disease, pr;ouml;staglan-dins are mucosal protective whereas leukotrienes (LT) are proinflammatory. Recent evidence suggests that the formation and action of LTs are calcium-dependent, whereas the formation and action of prostaglandins are not. A calcium channel blocker, verapamil, had a muco-sal-protective effect experimentally induced colitis in rats. In this study we examined the role of another type of calcium channel blocker, diltiazem (DLTZ), as a the;not;rapeutic agent on acetic acid (AA)-induced colitis in rats. Methods: Male Swiss Albino rats were divided into the 4 groups (n=10). I-Rats were administered 1 ml 4%AAint-rarectally, II-DLTZ was given i.m., in a dose of 2 mg/kg, for 7 consecutive days before instillation ofAA, III-DLTZ was given im, in. a dose of 2 mg/kg plus indometacin 5 mg/kg s.c, for 7 consecutive days before instillation of AA. In group TV rats were administered 1 ml of saline alone intrarectally. The rats were sacrificed two days later and the distal co;not;lons were scored (normahgrade 1, severe: 4) macroscopi-cally and tissue myeloperoxidase (MPO) activity was de;not;termined. Results: While no macroscobic injury occured in group fourth, mucosal injury occured in the first-group more than the second and third groups and was statistically meaningful (p;gt;0,01). While MPO activity was markedly high in the first group, it was found low in the second and third groups according to the first group which was statistically meaningful (p;lt;0,01). In conclusion: Diltiazem plays a protective role onAA-in-duced colitis in rats. Inhibition of endogenous PG biosynthesis has no effect on this protection. İltihabı barsak hastalığında prostaglandinler mu¬koza koruyucu, oysa leukotrienler (LT) proinflamatuar-dır. Yeni bulgular LT'lerin oluşum ve etkilerinin kalsi¬yuma bağımlı, prostaglandinlerin ise bağımlı olmadığı¬nı göstermiştir. Bir kalsiyum kanal blokeri olan verapa-milin sıçanlardaki deneysel kolitte mukoza koruyucu et¬kisi vardı. Bu çalışmada diğer bir tip kalsiyum kanal, blokeri olan diltiazemin (DLTZ), sıçanlarda geliştirilen asetik asite (AA) bağlı deneysel kolitte terapötik etkisi araştırılmıştır. Metotlar: Erkek Swiss Albino sıçanlar dört gruba ayrıl¬mışlardır (n=10). I-Sıçanlara 1 mi %4 AA rektal yolla ve¬rilmiştir. II-AA. verilmeden önce 7 gün boyunca 2 mg/kg dozda im olarak DLTZ verilmiştir. III- AA verilmeden önce 7 gün boyunca 2 mg/kg dozda DLTZ'e ek olarak 5 mg/kg indometacin sc. yolla verilmiştir. IV. grupta sı¬çanlara sadece rektal yolla 1 mi. serum fizyolojik veril¬miştir. 2 gün sonra sıçanlar sakrifiye edilmişler ve distal kolonları çıkarılarak makroskopik olarak skorlanmıştır (Normal: grade 1, şiddetli: 4) ve doku myeloperoksidaz (MPO) aktivitesi tayin edilmiştir. Sadece serum fizyolo¬jik verilenlerde makroskopik hasar oluşmazken, AA veri¬len birinci grupta mukozal hasar, ikinci ve üçüncü grup¬lara göre anlamlı olarak fazla gelişmiştir (p>0,01). MPO aktivitesi ise birinci grupta belirgin olarak yüksek sapta¬nırken, ikinci ve üçüncü gruplarda birinci gruba göre anlamlı olarak düşük saptanmıştır (p>0,01). Sonuç olarak; sıçanlarda AA ile oluşturulan kolitiste dil¬tiazem, koruyucu bir rol oynamıştır. Endojen prostag¬landin biosentezinin inhibisyonunun bu koruyuculuk üzerine etkisi yoktur.

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    Authors: Herdem, Mustafa;

    Tez (Uzmanlık) -- Çukurova Üniversitesi, Adana, 1990. 39 s. : rnk. res. ; 30 cm. Kaynakça (s. 36-39) var. TEZ876 …

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    Authors: Unver-Somer, N; Kaya, GI; Sarikaya, B; Onur, MA; Ozdemir, C; Demirci, B; Baser, KHC;

    The composition of the essential oil produced from the flowering aerial parts of Haplophyllum megalanthum Bornm. (Rutaceae), endemic to Turkey, was analyzed by GC and GC-MS. Among the fifty-eight compounds constituting about 91.7 % of the essential oil, the main components were characterized as palmito-gamma-lactone (45.8 %), octadecatrienoic acid (10.7 %), linoleic acid (6.5 %), octadecatetraenoic acid (6.3 %) and nonacosane (4.8 %).

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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Arıcı, İsmet; Korukçu, Abdurrrahim; Gündoğdu, Kemal Sulhi;
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Bursa Uludag Univers...arrow_drop_down
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Bursa Uludag Univers...arrow_drop_down
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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    Authors: Yeşildağ, Cemil;

    Bu çalışmada Ege Üniversitesi Tıp Fakültesi Göğüs Cerrahisi Anabilim Dalı’nda torakotomi geçiren hastalarda KPTA ağrı insidansının belirlenmesi amaçlandı. Ayrıca KPTA seyri, şiddeti, özellikleri, ağrının günlük yaşama etkisi ve analjezik kullanımı araştırıldı. Ege Üniversitesi Tıp Fakültesi Göğüs Cerrahisi Anabilim Dalı’nda Ocak 2007 ile Ekim 2009 tarihleri arasında torakotomi operasyonu geçiren 233 hasta incelendi. Birden fazla operasyon geçiren, ölüm nedeniyle kaybedilen, torakotomi dışında cerrahi girişim geçiren hastalar çalışmaya dahil edilmedi. Hastaların demografik verileri (yaş, cins, BMI), hastalık tanısı, geçirilen cerrahi girişim tipi, operasyon tarihi hasta dosyalarından elde edilen bilgiler eşliğinde kaydedildi. Çalışmaya dahil edilen tüm hastalar telefon ile arandı ve telefon ile ulaşılabilen hastalara geçirdikleri cerrahi işleme bağlı ağrı duyup duymadıkları soruldu. Torakotomiye bağlı ağrı duyduğunu bildiren hastalar görüşmeye çağırıldı ve ağrılarının değerlendirilmesinde Ağrı Sorgulama Formu (6) kullanıldı. Ege Üniversitesi Tıp Fakültesi Göğüs Cerrahisi Kliniği’nde torakotomi geçiren 233 hastadan 74 hasta çalışmaya dahil edilmedi: 27 hasta kaybedilmişti, 47 hasta birden fazla operasyon geçirmişti. 159 hasta çalışmaya dahil edildi ve telefon ile arandı. 47 hastaya ulaşılamadı, 112 hastaya telefon ile ulaşıldı. Yanıt alınabilen hasta oranı % 70.4 bulundu. Telefon ile görüşülen 112 hastadan 63 hasta geçirilen torakotomiye bağlı ağrı duyduğunu bildirdi, yanıt alınan hastalarda KPTA insidansı % 56 bulundu. Ağrı duyduğunu bildiren 63 hastadan 49 hasta görüşmeye geldi. 49 hastanın Ağrı Sorgulama Formu’na verdiği yanıtlara göre KPTA gelişen hastaların %69.4 kadarında ağrı şiddeti hafif, %26.5 kadarında ağrı şiddeti orta, %4.1 kadarında ise ağrı derecesi şiddetli bulundu. Bu hastalar içinde %89.7 hasta ağrısının zamanla azaldığını bildirdi. %38.7 hasta ağrısına yönelik analjezik kullanmakta idi, %24.4 hasta ağrının en kötü medikal problem olduğunu ve %24.4 hasta ağrının günlük aktivitesini kısıtladığını bildirdi. Nöropatik ağrı semptomlarının oranının %4 ile %61.2 arasında değiştiği görüldü. Sonuç olarak torakotomi geçiren hastalarda KPTA’nın %56 oranında görüldüğü, hastaların çoğunda ağrının hafif ve orta şiddette olduğu, %24 oranında günlük aktiviteyi kısıtlayabildiği görüldü. KPTA gelişimi, bu duruma neden olan periferik ve santral sinir sistemi değişikliklerini önleme konularında bilgilerimiz artıncaya kadar hastaların preoperatif olarak KPTA gelişme olasılığı ve sonuçları hakkında yeterli bilgilendirilmesi gerektiği kanısına varıldı.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ege University Insti...arrow_drop_down
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Say, Bahar; Ergün, Ufuk; Yıldız, Ayşe; Alpua, Murat; +2 Authors

    Objectives: The aim of this study was to test the utility and validity of the full cup test (FCT) to assess the severity of pain in subjects with painful diabetic peripheral neuropathy (PDPN). Methods: Subjects with diabetic PDPN were enrolled for this prospective, cross-sectional study. Other causes of PDPN and subjects with cognitive impairment were excluded. The diagnosis of neuropathic pain was made using the results of a physical examination and the Douleur Neuropathique 4 questionnaire. Pain severity was assessed with a FCT and a visual analog scale (VAS) administered before and after treatment. The correlation of FCT with VAS was evaluated to examine validity. Results: A total of 43 (33 female, 10 male) subjects were included. The mean age was 61.9±8.25 years and the mean disease duration was 13.02±7.6 years. Type I diabetes mellitus (DM) was present in 2 (4.7%) subjects and Type II DM in 41 (95.3%) subjects. The mean glycated hemoglobin level was 8.9±1.9 mmol/mol. When the mean VAS and FCT scores were analyzed, the results were 6.7±2.05 and 66.35±23.2, respectively, pretreatment and 4.6±2.2 and 41.36±23.5 posttreatment, which were both statistically significant (p<0.001, p<0.001). The mean control period was 23.4 days (min–max: 15-30 days). The VAS and FCT scores in pretreatment and posttreatment demonstrated a high positive correlation (rs =0.86, p<0.001; rs =0.843, p<0.001). Conclusion: The FCT can be useful to detect pain severity in PDPN. Amaç: Dolu bardak testinin (DBT) ağrılı diyabetik periferal nöropati (ADPN)’de kullanımını ve geçerliliğini test etmek. Gereç ve Yöntem: Bu kesitsel ve prospektif çalışmaya ADPN olan olgular alındı. Çalışma popülasyonunda periferal nöropati yapacak diğer nedenler ve kognitif yetmezlik dışlandı. Periferik nöropati tanısı muayene ve Douleur Neuropathique 4 (DN4) anketi kullanılarak gösterildi. Ağrı şiddeti tedavi öncesi ve sonrasında DBT ve Vizüel Analog Skala (VAS) ile değerlendirildi. Geçerlilik için DBT’nin VAS ile korelasyonuna bakıldı. Bulgular: Çalışmaya 43 (33 kadın, 10 erkek) olgu alındı. Ortalama yaş 61.9±8.25, ortalama hastalık süresi 13.02±7.6 yıldı. Tip I DM 2 (%4.7) olguda, Tip II DM 41 (%95.3) olguda mevcuttu. HbA1c düzeyi ortalama 8.9±1.9 mmol/mol’du. Ağrı şiddetinin değerlendirilmesinde kullanılan VAS ve DBT tedavi öncesi ve sonrası karşılaştırıldığında ortalama skorlar tedavi öncesinde 6.7±2.05, 66.35±23.2, tedavi sonrasında ise 4.6±2.2, 41.36±23.5 bulundu. Sonuçlar istatistiksel olarak anlamlıydı (p<0.001, p<0.001). Olgularda ortalama kontrol süresi 23.4 (minimum–maksimum: 15–30) gün oldu. Ağrı şiddet ölçeği DBT, tedavi öncesi ve sonrasında VAS ile yüksek korele bulundu (rs =0.86, p<0.001; rs =0.843, p<0.001). Sonuç: Dolu bardak testi ADPN’de ağrı şiddetini belirlemede kullanışlı olabilir.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Kırıkkale Üniversite...arrow_drop_down
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    Authors: Çavuşoğlu, Güneş Dorukhan;

    New biomarkers that will guide the diagnosis of rheumatoid arthritis are being studied and early diagnosis and treatment of the disease is aimed. Similar pathogenetic mechanisms of periodontitis and RA have been demonstrated. Disease activities of patients with RA who have periodontal disease tend to be worse. Previous studies suggest that calprotectin may be a valuable biomarker for the diagnosis and prognosis of RA. The relationship between calprotectin and disease activity in patients with periodontitis is known. In addition, several studies have shown that the salivary calprotectin level is high in patients with chronic periodontitis. A study showing the relationship between salivary calprotectin levels and disease activity in patients with RA has not been found in the literature so far. In this study, our aim is to evaluate the disease activity with serum and salivary calprotectin levels in patients with RA, and secondly, to evaluate periodontitis in these patients and to reveal whether serum and salivary calprotectin levels are related to periodontitis. 76 patients diagnosed with RA (Female/Male: 59/17) according to the 2010 ACR/EULAR classification criteria, 24 patients diagnosed with SS (F/M: 24/0) according to the 2016 ACR-EULAR classification criteria as the patient control group, and 40 healthy adults (F/M: 24/0) as healthy control group, who applied to the Medipol University Faculty of Medicine Rheumatology Department outpatient clinic, were included in the study. Demographic, clinical and laboratory data of the cases were recorded in the patient follow-up form, and periodontitis examination was performed after taking serum and saliva samples to measure the calprotectin levels simultaneously. Intergroup analyzes were evaluated with Student-T test and Mann-Whitney U test. The correlations between patient and physician-derived scales were evaluated with the Spearman correlation test. In patients with RA, serum calprotectin value was found to be higher in the group with high disease activity than in the group with low disease activity [HDA and LDA: 11.5 (0.78-38.23); 8.3 (1.6-24.4) (p:0.02)]. Mean serum calprotectin values were found to be higher in the RA group than in the other two groups, and there was a statistical difference between the RA group and the SS group, but no statistical difference was found between the RA group and the healthy control group [RA, SS, and HC, respectively: 13.6 (9.8); 8.1 (7.5) and 10.9 (6.02) (p:0.01)]. Median salivary calprotectin levels in patients with RA were found to be higher in patients with periodontitis than in patients without periodontitis [Periodontitis stage I and Periodontitis stage II-IV, respectively: 27.3 (1.6-40.74); 31.7 (0.64-75.85) (p:0.04)]. Serum calprotectin levels were found to be higher in the rheumatoid arthritis patient group than in the healthy and patient control group, and were correlated with disease activity. On the other hand, salivary calprotectin values in patients with rheumatoid arthritis were found to be lower than those of the healthy and patient control group. While periodontal inflammation was correlated with salivary calprotectin values in patients with rheumatoid arthritis, no such relationship was found in the other two groups. Similar to other studies, this study showed that serum calprotectin levels were positively correlated with disease activity markers. Romatoid artrit hastalığının tanısında yol gösterecek yeni biyobelirteçler üzerinde çalışılmakta ve hastalığın erken teşhisi ve tedavisi hedeflenmektedir. Periodontit ve RA'nın benzer patogenetik mekanizmaları gösterilmiştir. Periodontal hastalığı olan RA'lı hastaların hastalık aktiviteleri daha kötü seyretmektedir. Önceki çalışmalar kalprotektinin RA tanısı ve prognozu için değerli bir biyobelirteç olabileceğini göstermektedir. Periodontiti olan hastalarda kalprotektinle hastalık aktivitesi arasındaki ilişki bilinmektedir. Ayrıca kronik periodontiti olan hastalarda tükürük kalprotektin düzeyinin de yüksek olduğu birkaç çalışmada gösterilmiştir. RA tanılı hastalarda tükürükteki kalprotektin düzeyleriyle hastalık aktivitesinin ilişkisini gösteren bir çalışma şu ana dek literatürde bulunmamaktadır. Bu çalışmada amacımız RA tanılı hastalarda serum ve tükürük kalprotektin düzeyleriyle hastalık aktivitesini değerlendirmek, ikincil olarak da bu hastalarda periodontiti değerlendirerek serum ve tükürük kalprotektin düzeylerinin periodontitle ilişkisi olup olmadığını ortaya koymaktır. Medipol Üniversitesi Tıp Fakültesi Romatoloji Bilim Dalı polikliniğine başvuran, 2010 ACR/EULAR sınıflandırma kriterlerine göre RA tanısı almış 76 hasta (K/E: 59/17), hasta kontrol grubu olarak 2016 ACR-EULAR sınıflandırma kriterlerine göre Sjögren sendromu tanısı almış 24 hasta (K/E: 24/0) ve sağlıklı kontrol grubu olarak 40 yetişkin (K/E: 25/15) çalışmaya dahil edildi. Olguların demografik, klinik ve laboratuvar verileri hasta takip formuna kaydedildi ve eş zamanlı olarak kalprotektin için serum ve tükürük örneği alındıktan sonra periodontit muayenesi yapıldı. Gruplar arası analizler Student-T testi, Mann-Whitney U testi; hasta ve doktor kökenli ölçekler arası korelasyonlar Spearman korelasyon testiyle değerlendirildi. RA'lı hastalarda serum kalprotektin değeri, yüksek hastalık aktivitesi olan grupta, düşük hastalık aktivitesi olan gruba göre daha yüksek saptandı [YHA ve DHA: 11,5 (0,78-38,23); 8,3 (1,6-24,4) (p:0,02)]. Ortalama serum kalprotektin değerleri RA grubunda diğer iki gruba göre daha yüksek saptandı ve RA grubuyla SS grubu arasında istatistiksel fark saptanırken, RA grubu ile sağlıklı kontrol grubu arasında istatistiksel fark saptanmadı [RA, SS ve SK sırasıyla: 13,6 (9,8); 8,1 (7,5) ve 10,9 (6,02) (p:0,01)]. RA tanılı hastalarda ortanca tükürük kalprotektin düzeyleri, periodontiti olan hastalarda periodontiti olmayanlara göre daha yüksek saptandı [Periodontit evre I ve Periodontit evre II-IV sırasıyla: 27,3 (1,6-40,74); 31,7 (0,64-75,85) (p:0,04)]. Romatoid artrit hasta grubunda serum kalprotektin değerleri sağlıklı ve hasta kontrol grubuna göre yüksek saptanmış ve hastalık aktivitesiyle korele bulunmuştur. Buna karşılık romatoid artritli hastalarda tükürük kalprotektin değerleri sağlıklı ve hasta kontrol grubuna göre düşük saptanmıştır. Romatoid artritli hastalarda periodontal enflamasyon tükürük kalprotektin değerleri ile korele çıkarken, diğer iki grupta böyle bir ilişki saptanmamıştır. Bu çalışma diğer çalışmalara benzer şekilde serum kalprotektin düzeylerinin hastalık aktivite belirteçleriyle pozitif yönde korele olduğunu göstermiştir.

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    Authors: Yıldırım, Mehmet;

    Bu yazıda, Yalazı/Balıkesir talk yatağından alınan cevher numunesinin zenginleştirme çalışmalarının sonuçları sunulmuştur. Manyetik mineral taşıyan serbestleşmiş tanecikler bir yüksek alan şiddetli yaş manyetik ayırıcı ile uzaklaştırılmıştır. Bu deneyde, demir içeriği bazında % 90,82 ayırma verimine ulaşılmıştır. Cevher içindeki manyetik olmayan yantaş mineralleri, doğal yüzebilirliği olan yaprağımsı talk mineral taneciklerinden flotasyon ile ayrılmışlardır. Bu çalışmalarla, % 6,99 demir içeren orijinal cevher numunesinden % 69,75 flotasyon verimi ile % 0,75 demir içeren bir talk konsantre elde edilebilmiştir. Son konsantrenin manyezit ve talk içerikleri termogravimetrik analizler ile belirlenmiştir. In this paper, results of the beneficiation studies of the ore sample taken from the Yalazı/Balıkesir talc deposit were reported. A high intensity wet magnetic separator discarded magnetic mineral bearing particles liberated. In this experiment, 90,82 % separation recovery based on the iron content was achieved. The non-magnetic gangue minerals in the ore were separated from the foliated talc minerals that are naturally floatable. A talc concentrate containing 0,75 % iron was obtained from the original ore sample containing 6,99 % iron with 69,75 % flotation recovery. Magnesite and talc contents of the final concentrate were determined by the thermogravimetric analysis.

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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Çukurova University ...arrow_drop_down
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    Authors: Yıldırım, İsmail;

    Keywords: Electric Arc Furnace, Oxygen Blowing. Nowadays, steel production with electric arc furnaces are gaining importance in Turkey and throughout the world. At present 40 % of the world's steel production are being produced by electric arc furnaces. Steel production with electric arc furnace has been brought about advantages such as high productivity, low production cost, easy raw materials handling and charging and simple production, high rate of energy saving, lower investment cost which have led to spread more easily. The aims of this study are to investigate and apply some of the recent developments in steel making technology with electric arc furnaces to improve the efficiency of 3 ton capacity model electric arc furnace, which is unefficient, without investing considerably to the plant for facilities in order to gain energy and raw materials savings. The developments which was applied to the model electric arc furnace include decarburizing by blowing oxygen to scrap charge and molten steel, scrap classificatio