【研究分野】微生物学、食品衛生学

We have developed an optical imaging system based on the coherent activities of intrinsic optical signals for the measurement of the neuronal activities in the visual cortex. In the present study, we have applied the system for the investigation of the neuronal basis fo...

【研究分野】歯内治療学、保存修復学、口腔細菌学

【研究分野】口腔外科、口腔顎顔面外科、細胞生物学

The identification of the brain morphological alterations that play important roles in neurodegenerative/neurological diseases will contribute to our understanding of the causes of these diseases. Various automated software programs are designed to provide an automatic ...

Streptococcus intermedius is an oral commensal and a cause of systemic pyogenic disease. A part of the organism possessed curly-like fimbriae. Genomic analyses showed that the operon of the fimbriae was a typical pilus gene operon and constructed of at least 4 ORFs. A f...

The combination of MUC1, MUC2, MUC4 and MUC5AC expression is useful for early detection and evaluation of the potential for malignancy of pancreatobiliary neoplasms. Regarding the mechanism of mucin expression, we have recently reported that expression of the mucin gene...

【研究分野】口腔がん、エピジェネティクス、DNAメチル化、ヒストン化学修飾、スプライシング異常

Gliomas are one of the most common intracranial tumors. Gliomas exhibit a progression associated with widespread infiltration into surrounding neuronal tissues. However, the molecular mechanisms that stimulate the invasion of glioma cells are not fully understood. We es...