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This database includes the raw data linked with the paper ���Reading Skills of Children with Dyslexia Improved Less than Expected During the COVID-19 lockdown in Italy��� published in ���Children���. In this paper, we reported the modification of reading speed and accuracy in children with Specific Learning Disorders during the COVID-19 lockdown in Italy (measured with word, non-word and text reading standardized tests administered before and after the ���lockdown���) and answers to an ad hoc questionnaire regarding their experience during the lockdown period. The reading assessment was performed through three tasks. The first two tasks (i.e., reading aloud a list of words and a list of non-words) were derived from the Battery for the Assessment of Developmental Dyslexia and Dysorthography-2 (DDE-2 Battery by Sartori et al.) to assess reading speed (syllables per second) and accuracy (number of errors). The third task was derived from the Assessment of Reading and Comprehension Skills for Elementary and Middle School (MT-3-Clinic tasks by Cornoldi and Carretti) and it consists of reading a text aloud to assess reading speed (syllables per second) and accuracy (number of errors). An ad hoc questionnaire provided a detailed characterization of the online school delivered during the lockdown period (March���June 2020), including which kinds of remote education were implemented (e.g., online vs. pre-recorded lessons), major challenges in managing online school (e.g., online platform, connection, family management), and parents��� perception of their children learning trajectories. The questionnaire was filled in by parents as well as by children with the help of a dedicated researcher. Between 59 to 63% of children with dyslexia did not reach the average expected increase of reading skills. According to their parents, they also showed greater social isolation and fewer worries about the pandemic and the school���s closure. Our data indicate that children with dyslexia are at increased risk of consequences on their learning potential in case of school closure. They also seem to have a peculiar psychological experience of school closure. Funding: Ricerca Corrente 2020, Ministry of Health (Italy)

Data set from the article Dozio E, Sitzia C, Pistelli L, Cardani R, Rigolini R, Ranucci M, Corsi Romanelli MM. Soluble Receptor for Advanced Glycation End Products and Its Forms in COVID-19 Patients with and without Diabetes Mellitus: A Pilot Study on Their Role as Disease Biomarkers. J Clin Med. 2020 Nov 23;9(11):3785. doi: 10.3390/jcm9113785. PMID: 33238596; PMCID: PMC7700384. Abstract The receptor for advanced glycation end products (RAGE), a well-known player of diabetes mellitus (DM)-related morbidities, was supposed to be involved in coronavirus disease-19 (COVID-19), but no data exist about COVID-19, DM, and the soluble RAGE (sRAGE) forms. We quantified total sRAGE and its forms, the endogenously secretory esRAGE and the membrane-cleaved cRAGE, in COVID-19 patients with and without DM and in healthy individuals to explore how COVID-19 may affect these molecules and their potential role as biomarkers. Circulating sRAGE and esRAGE were quantified by enzyme-linked-immunosorbent assays. cRAGE was obtained by subtracting esRAGE from total sRAGE. sRAGE, esRAGE, cRAGE, and the cRAGE/esRAGE ratio did not differ between DM and non-DM patients and had the same trend when compared to healthy individuals. Levels of total sRAGE, cRAGE, and cRAGE/esRAGE ratio were upregulated, while esRAGE was downregulated. The lack of difference between DM and non-DM COVID-19 patients in the levels of sRAGE and its forms supports the hypothesis that in COVID-19 the RAGE system is modulated regardless of glycemic control. Identifying how sRAGE and its forms associate to COVID-19 prognosis and the potential of RAGE as a therapeutic target to control inflammatory burden seem of relevance to help treatment of COVID-19.

O presente trabalho investiga o comportamento dos investidores nos mercados financeiros em períodos de crise. Em particular, este estudo investiga quais os determinantes sociodemográficos do comportamento dos investidores durante o período de crise fruto da pandemia COVID-19, usando o principal índice português, o PSI 20, como objeto de estudo. Os dados foram disponibilizados por uma das principais instituições financeiras do mercado português e contêm transações de 15 943 indivíduos para os anos de 2019 e 2020. Através de testes ANOVA e do método dos mínimos quadrados, é concluído que há efetivamente variáveis sociodemográficas que impactam o comportamento dos investidores nos mercados financeiros em períodos de crise. Investidores do género masculino são os mais ativos no mercado bolsista em períodos de crise e o estado civil não se relaciona com a atividade nos mercados de capitais. Riqueza, educação e a idade do investidor têm um impacto positivo nos montantes investidos em períodos de crise e a antiguidade do cliente tem um impacto negativo. Relativamente às características do individuo perante a instituição, a posse de uma conta de depósito a prazo com a instituição tem um impacto negativo no montante investido no mercado de capitais em períodos de crise. Já a posse de pelo menos um empréstimo com a instituição demonstra ter um impacto positivo na variável, com os investidores que possuem empréstimos a investir mais no mercado de capitais durante a pandemia. This paper investigates the sociodemographic characteristics of capital markets investors' behaviour during the pandemic period. For this purpose, we use data provided by a major Portuguese financial institution that comprises data for 15,943 individuals' transactions during 2019 and 2020. Using ANOVA tests and OLS estimations it was concluded that there are sociodemographic variables that impact investors’ behaviour towards the market in crisis periods. Male investors are more active during crisis periods than female investors and marital status was seen to not impact trading activity. Investors' wealth, education and age influence invested amounts in a positive way whereas client seniority has a negative impact. The possession of a savings account was seen to impact trading activity negatively while the possession of a loan had a positive impact on amounts traded during the pandemic.

Dataset from the comment Nania T, Dellafiore F, Caruso R, Barello S. Risk and protective factors for psychological distress among Italian university students during the COVID-19 pandemic: The beneficial role of health engagement. Int J Soc Psychiatry. 2020 Jul 28:20764020945729. doi: 10.1177/0020764020945729. Epub ahead of print. PMID: 32721256. Introduction We read with great interest the study by Torales et al. (2020) and colleagues on the impact of COVID-19 on the global and mental health of citizens across countries. They stated that global health initiatives should be employed to manage psychosocial stressors, particularly those related to the experience of isolation and quarantine among the general population. There have been reports on the psychological impact of the epidemic on citizens, patients, medical workforce, children, and older adults (Barello et al., 2020; Dubey et al., 2020; Garnier-Crussard et al., 2020; Li et al., 2020; Lima et al., 2020). However, few studies on the mental health status of Italian university students facing the epidemic has been conducted to date. At this regard, university students should be considered as a potentially higher risk population for mental health disorders related to the COVID-19 pandemic, as they were asked to deeply reframe their daily habits. The continuous spread of the epidemic, strict isolation measures, being often far from home and lack of interpersonal relationships across Italy, may have hugely affected the mental health of university students. Furthermore, university students, more than others social groups, had to tackle the ‘infodemic’ of misinformation about COVID-19, due to their higher social media exposure (Rovetta & Bhagavathula, 2020). The re-organization of learning activities and of their habits could represent a challenging demand for students, which requires adequate institutional responses to make them able to manage anxiety and stress. Therefore, we believe that a wider understanding of those factors that might contribute in exacerbating anxiety and poor mental health outcomes in university students is warranted to address this issue to provide high-quality, timely crisis-oriented psychological services to this vulnerable population (Tang et al., 2020). Specifically, further studies should encompass positive and negative determinants of students’ Covid-19–related distress.

An extended brief overviewing a bread swath of responses from higher educational institutions worldwide, to the COVID-19 pandemic.

As Empresas Familiares são uma forma única e particular de organização profundamente interessante devido ao seu próprio estilo de modelo de negócios, diferenças hierárquicas, valores e princípios. Consequentemente, a sua capacidade de inovar difere de outras formas de organização. Com a chegada da pandemia COVID-19, os modelos de negócios tiveram que atualizar as suas abordagens, inovando e agindo de acordo com os hábitos de consumo e restrições sanitárias. Mundialmente, algumas empresas tiveram que mudar, tendo na sua centralidade abordagens e mentalidades inovadoras, enquanto outras não conseguiram colocar esses mesmos mecanismos em ação. Esta dissertação e pesquisa tem como objetivo primordial analisar a capacidade de inovação das empresas familiares no que diz respeito à interação com o cliente e como a pandemia desequilibra o seu modelo. Além disso, com este estudo, espera-se que alguns resultados possam orientar outras empresas familiares sobre como enfrentar e interagir com algumas barreiras inovadoras e dar-lhes a capacidade de lidar com as mesmas. Family Businesses are a particular and unique form of organization deeply interesting due to their own business model style, hierarchical differences, values and principles. Consequently, their capacity to innovative differ from other types of organization. With the arrival of COVID-19 Pandemic, business models had to adapt their innovative approaches to act accordingly with consumer habits and sanitary restrictions. Worldwide, some businesses had to change, with innovative approaches and mindsets, while other could not bring those same mechanisms to action. This dissertation aims to analyze the capacity of family entities to innovation regarding their customer interaction and how the pandemic imbalance their model. Also, with this study, it is expected that some results might guide other family firms on how to deal and interact with the barriers and to give the capacity to deal with the same barriers.

ImagineThe internet stops workingelectricity is cutthe many screens which connect you to the world turn blackyou no longer have access to your bank accountor functioning credits cardsthe walls behind which you retreated fade awayand you find yourself under the open skynow you are like menothing but a “dangerous body” on the streetwhat can you do now?what must you do now?out in the open where an invisible virus lurks?you roamroam the city forfoodinformationand means to protect those you love

Interviews from Manara DF, Villa G, Korelic L, Arrigoni C, Dellafiore F, Milani V, Ghizzardi G, Magon A, Giannetta N, Caruso R. One-week longitudinal daily description of moral distress, coping, and general health in healthcare workers during the first wave of the COVID-19 outbreak in Italy: A quantitative diary study. Acta Biomed. 2021 Oct 5;92(S6):e2021461. doi: 10.23750/abm.v92iS6.12313. PMID: 34739455. Abstract Background and aim of the work .The fluctuation from day to day within a working week of moral distress, coping, and general health of frontline healthcare workers (HCWs) in facing the challenges of the COVID-19 pandemic has been poorly studied. This study described the weekly fluctuation from day to day of moral distress, coping, and general health in frontline HCWs who worked during the first epidemic wave (May-June 2020) of the COVID-19 pandemic in Italy. Methods: This study has an intensive longitudinal design, and a convenience sampling procedure was employed to enroll physicians, nurses, allied health professions, and healthcare assistants. Data collection was performed using diary encompassed four sections: a socio-demographic form (required only at the baseline data collection) and three scales to assess moral distress, coping, and general health. Results: Results confirmed poor perceived health and mild moral distress in frontline HCWs, especially in HCWs with offspring, during the initial phases of the COVID-19 pandemic and the stability of their daily perception over a working week regarding moral distress, general health, and avoidant coping strategy, while approach coping strategy reported a slight fluctuation over time. Conclusions: Accordingly, on the one hand, these results confirm that outcomes regarding mental health and moral distress are pretty stable and provide insights, on the other hand, regarding the possible organizational interventions to support approach coping strategy as it seems more susceptible to variation over time.

This record contains raw data related to the article "Evidence of SARS-CoV-2 transcriptional activity in cardiomyocytes of COVID-19 patients without clinical signs of cardiac involvement" Article abstract: We dissected the characteristics of SARS-CoV-2 cardiac tropism in autopsy heart samples of COVID-19 patients, deceased for respiratory failure without cardiac clinical phenotype. By multiple approaches, we detected viral localization into cardiomyocytes, which did not display cell death hallmarks. In addition, we demonstrated active viral transcription in cardiomyocytes by detecting both sense and antisense SARS-CoV-2 spike RNA. These findings suggest the need of a cardiologic surveillance in survived COVID-19 patients.