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  • Open Access
    Authors: 
    Zsuzsanna Heiner; Thomas Roland; Jérémie Léonard; Stefan Haacke; Géza I. Groma;
    Publisher: EDP Sciences
    Country: France

    The non-radiative energy transfer is shown to occur on a ∼3ps time scale for NADH in the folded form in H2O. Addition of methanol thermodynamically favours the open form, for which energy transfer does not occur.

  • Open Access English
    Authors: 
    Sayako Hirose; Takeru Makiyama; Dario Melgari; Dario Melgari; Yuta Yamamoto; Yuta Yamamoto; Yimin Wuriyanghai; Fumika Yokoi; Suguru Nishiuchi; Takeshi Harita; +14 more
    Publisher: HAL CCSD
    Country: France

    International audience; Background: Long QT syndrome type 3 (LQT3) is caused by gain-of-function mutations in the SCN5A gene, which encodes the α subunit of the cardiac voltage-gated sodium channel. LQT3 patients present bradycardia and lethal arrhythmias during rest or...

  • Open Access
    Authors: 
    A. J. Castro-Tirado; José L. Gómez; I. Agudo; Martín A. Guerrero; M. Bremer; J. M. Winters; Javier Gorosabel; R. Sanchez-Ramirez; S. Guziy; Martin Jelínek; +9 more
    Publisher: EDP Sciences

    We describe the evolution of of Swift J1644+57, whose unique X-ray properties have led several groups to interpret its behavior as corresponding to an extraordinary event of tidal disruption of a star by a supermassive black hole in the nucleus of a (z = 0.3545) galaxy,...

  • Open Access English
    Authors: 
    Mathieu eBaudonnat; Anna eHuber; Anna eHuber; Vincent eDavid; Mark Edwin Walton;
    Publisher: Frontiers Media S.A.
    Country: United Kingdom
    Project: WT

    Dopamine has long been tightly associated with aspects of reinforcement learning and motivation in simple situations where there are a limited number of stimuli to guide behaviour and constrained range of outcomes. In naturalistic situations, however, there are many pot...

  • Open Access English
    Authors: 
    Jean-Marc Berjeaud; Sylvie Chevalier; Margot Schlusselhuber; Emilie Portier; Clémence Loiseau; Willy Aucher; Olivier Lesouhaitier; Julien Verdon;
    Publisher: Frontiers Media S.A.
    Country: France

    International audience; Legionella pneumophila, the major causative agent of Legionnaires' disease, is found in freshwater environments in close association with free-living amoebae and multispecies biofilms, leading to persistence, spread, biocide resistance, and eleva...

  • Open Access English
    Authors: 
    David L. Price; Louis Hennet; I. Pozdnyakova; Marie-Louise Saboungi;
    Publisher: HAL CCSD
    Country: France

    We review recent measurements of the microscopic dynamics of high-temperature liquids made with inelastic x-ray scattering and aerodynamic levitation of the samples. Phenomenological and theoretical interpretations are also discussed. Ми робимо огляд недавнiх дослiджень...

  • Open Access
    Authors: 
    Gerhard Buck-Sorlin; Mickaël Delaire;
    Publisher: Frontiers Media SA
    Country: France

    THE PURPOSE OF MODELS AND THE MODELING EXERCISE In order to better understand the significance of models in practical horticulture we have to put ourselves into the position of the horticulturist (orchard grower, consultant . . . ) and appreciate first of all some skept...

  • Open Access English
    Authors: 
    Marie-Hélène Chevrier; Chloé Huvet;
    Publisher: Association Via@
    Country: France

    International audience; ‘We could meet at the Saint Sophia mosque. – Like we were tourists,’ suggests James Bond to Russian agent Tatiana Romanova in From Russia with Love. Since 1962 and the release of Dr. No, tourism and tourists have played an important role in the J...

  • Publication . Article . Other literature type . 2017
    Open Access
    Authors: 
    Stefano Pierini; Renzo Perales-Linares; Mireia Uribe-Herranz; Jonathan Pol; Laurence Zitvogel; Guido Kroemer; Andrea Facciabene; Lorenzo Galluzzi;
    Publisher: Informa UK Limited

    DNA-based vaccination is a promising approach to cancer immunotherapy. DNA-based vaccines specific for tumor-associated antigens (TAAs) are indeed relatively simple to produce, cost-efficient and well tolerated. However, the clinical efficacy of DNA-based vaccines for c...

  • Open Access English
    Authors: 
    Cecilia Virginia Gheran; Sorina Nicoleta Voicu; G Rigaux; Maité Callewaert; Françoise Chuburu; Anca Dinischiotu;
    Publisher: HAL CCSD
    Country: France

    Abstract Gadolinium nanoparticles (GdNPs) are potential agents for MRI of lymph nodes. The aim of this study was to evaluate the in vitro effects of 1 μM, 2.5 μM and 5 μM of GdDOTA⊂CS-TPP/HA and GdDOTP⊂CS-TPP/HA NPs on A20 lymphocyte cells exposed for 6 and 24 hours. T...