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586 Research products, page 1 of 59

  • Publications
  • Research software
  • Open Access
  • 03 medical and health sciences
  • Archivio Istituzionale della Ricerca dell'Università degli Studi di Milano

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  • Open Access
    Authors: 
    Luca Marelli; Giuseppe Testa;
    Publisher: American Association for the Advancement of Science (AAAS)
    Country: Italy

    On 25 May 2018, the European Union (EU) regulation 2016/679 on data protection, also known as the General Data Protection Regulation (GDPR), will take effect. The GDPR, which repeals previous European legislation on data protection (Directive 95/46/EC) ( 1 ), is bound t...

  • Open Access English
    Authors: 
    Peter Rzehak; Marcela Covic; Richard Saffery; Eva Reischl; Simone Wahl; Veit Grote; Martina Weber; Annick Xhonneux; Jean-Paul Langhendries; Natàlia Ferré; +7 more
    Publisher: Nature Publishing Group
    Countries: Germany, Italy
    Project: EC | META-GROWTH (322605), EC | DYNAHEALTH (633595), EC | EARLYNUTRITION (289346)

    Abstract Adiposity and obesity result from the interaction of genetic variation and environmental factors from very early in life, possibly mediated by epigenetic processes. Few Epigenome-Wide-Association-Studies have identified DNA-methylation (DNAm) signatures associa...

  • Open Access English
    Authors: 
    Laura Rustioni; Letizia Rocchi; Eugenio Guffanti; Gabriele Cola; Osvaldo Failla;
    Publisher: American Chemical Society
    Country: Italy
    Project: EC | INNOVINE (311775)

    Sunburn can affect grape quality both for chemical modifications and by visual impact of the browning. Optical properties of 17 white grape accessions were investigated in the visible region using a noninvasive instrument. Reflectance spectra were obtained using a Jaz S...

  • Open Access
    Authors: 
    Fabrizio Gardoni; Elisa Zianni; Anna Eramo; Pier Luigi Canonico; Monica Di Luca;
    Publisher: Elsevier BV
    Country: Italy
    Project: EC | REPLACES (222918)

    In the last decade, several neuroprotective therapies have been proposed for Parkinson's disease and rasagiline was indicated as one of the most promising candidates by preclinical studies. The drug has already been tested in phase III clinical studies (the ADAGIO study...

  • Open Access English
    Authors: 
    Camilla Cattaneo; Giorgio Gargari; Ranjan Koirala; Monica Laureati; Patrizia Riso; Simone Guglielmetti; Ella Pagliarini;
    Publisher: Nature Publishing Group
    Country: Italy

    AbstractFairly poor data are available on the relationship between taste perception, food preferences and oral microbiota. In the present study, we investigated the hypothesis that subjects with higher responsiveness to 6-n-propylthiuracil (PROP) might be characterized ...

  • Publication . Article . Preprint . 2017 . Embargo End Date: 01 Jan 2017
    Open Access
    Authors: 
    Fabio Giavazzi; Chiara Malinverno; Salvatore Corallino; Francesco Ginelli; Giorgio Scita; Roberto Cerbino;
    Publisher: arXiv
    Country: Italy
    Project: EC | THE METAENDOMATRIX (268836), EC | PIFS (618399)

    We thank S Henkes for useful discussions. FGia and RC acknowledge funding from the Italian Ministry of University and Scientific Research (MIUR) under the program Futuro in Ricerca—Project ANISOFT (RBFR125H0M) and from Regione Lombardia and CARIPLO foundation under the ...

  • Open Access English
    Authors: 
    Valeria De Matteis; Mariafrancesca Cascione; Loris Rizzello; Daniela Manno; Claudia Di Guglielmo; Rosaria Rinaldi;
    Publisher: MDPI AG
    Country: Italy
    Project: EC | PANDORA (850936)

    Simple Summary Polyphenols are present in a broad variety of plants, and they are known to possess anti-inflammation and anticancer properties. We used extracts from Laurus nobilis to synthetize gold nanoparticles (Au NPs), on which polyphenols were absorbed to form a s...

  • Open Access English
    Authors: 
    Steven B. Condliffe; Irene Corradini; Davide Pozzi; Claudia Verderio; Michela Matteoli;
    Publisher: American Society for Biochemistry and Molecular Biology
    Country: Italy
    Project: EC | EUROSPIN (241498)

    In addition to its primary role as a fundamental component of the SNARE complex, SNAP-25 also modulates voltage-gated calcium channels (VGCCs) in various overexpression systems. Although these studies suggest a potential negative regulatory role of SNAP-25 on VGCC activ...

  • Open Access English
    Authors: 
    Nicola Manfrini; Sara Ricciardi; Roberta Alfieri; Gabriele Ventura; Piera Calamita; Andrea Favalli; Stefano Biffo;
    Publisher: Elsevier
    Country: Italy

    The transition from a naive to an effector T cell is an essential event that requires metabolic reprogramming. We have recently demonstrated that the rapid metabolic changes that occur following stimulation of naive T cells require the translation of preexisting mRNAs. ...

  • Open Access English
    Authors: 
    Haan, H.G. de; Vlieg, A.V.; Lotta, L.A.; Gorski, M.M.; Bucciarelli, P.; Martinelli, I.; Baglin, T.P.; Peyvandi, F.; Rosendaal, F.R.; INVENT Consortium;
    Publisher: Wiley Blackwell Publishing
    Countries: Netherlands, France, Italy

    International audience; Essentials Deep vein thrombosis (DVT) has a large unknown genetic component. We sequenced coding areas of 734 hemostasis-related genes in 899 DVT patients and 599 controls. Variants in F5, FGA-FGG, CYP4V2-KLKB1-F11, and ABO were associated with D...