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119 research outcomes, page 1 of 12
  • publication . Article . Other literature type . 2009
    Open Access English
    Authors:
    Ladislav Šenolt; Jiří Vencovský; Karel Pavelka; Caroline Ospelt; Steffen Gay;
    Publisher: Elsevier

    Advances in the current knowledge of pathogenetic mechanisms of rheumatoid arthritis have contributed to the development of biological therapy, and translated research findings into clinical practice. TNF-alpha (infliximab, etanercept, adalimumab), IL-1 (anakinra) and I...

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  • publication . Article . Other literature type . 2009
    Open Access
    Authors:
    Brian D. Poole; Amanda Templeton; Joel M. Guthridge; Eric J. Brown; John B. Harley; Judith A. James;
    Persistent Identifiers
    Publisher: Elsevier BV

    Serologic association, cross-reactivity of select EBV-specific antibodies with SLE autoantigens, SLE-like autoimmunity after immunization with EBV peptides, increased EB viral load in SLE patients, and SLE-specific alterations in EBV humoral and cellular immunity implic...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Haroon Khan; Antoni Sureda; Tarun Belwal; Sümeyra Çetinkaya; Ipek Süntar; Silvia Tejada; Hari Prasad Devkota; Hammad Ullah; Michael Aschner;
    Persistent Identifiers

    In addition to protecting body from infections and diseases, the immune system produces auto-antibodies that can cause complex autoimmune disorders, such as Type I diabetes, primary biliary cirrhosis, rheumatoid arthritis, and multiple sclerosis, to name a few. In such ...

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  • publication . Other literature type . Article . 2008
    Open Access English
    Authors:
    Wan-Uk Kim; Antoine G. Sreih; Richard Bucala;
    Persistent Identifiers

    Recent experimental and clinical studies have placed new emphasis on the role of the innate immune system in SLE. Nucleic acid-containing immune complexes activate the innate response by engaging specific Toll-like receptors (TLRs) and promote the generation of autoanti...

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  • publication . Other literature type . Article . 2018
    Restricted English
    Authors:
    Jan Willem Cohen Tervaert;
    Persistent Identifiers

    In the present review, recent findings regarding autoimmune/inflammatory syndrome by adjuvants (ASIA) are described. Patients with ASIA present with complaints such as fatigue, cognitive impairment, arthralgias, myalgias, pyrexia, dry eyes and dry mouth. During the last...

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  • publication . Other literature type . Article . 2011 . Embargo End Date: 01 Jan 2011
    Open Access
    Authors:
    Caroline Ospelt; Kris A. Reedquist; Steffen Gay; Paul P. Tak;
    Publisher: Elsevier

    Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction. Synovial fibroblasts are recognized as key cells in the pathogenesis of RA since they attract and activate immune cells and produce matrix degrading enzymes. Most notably synovial ...

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  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    James Michael Kelley; Jeffrey C. Edberg; Robert P. Kimberly;
    Persistent Identifiers
    Publisher: Elsevier BV

    Systemic lupus erythematosus (SLE) is a complex autoimmune disorder marked by an inappropriate immune response to nuclear antigens. Recent whole genome association and more focused studies have revealed numerous genes implicated in this disease process, including ITGAM,...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Melissa H. Roberts; Esther Erdei;
    Persistent Identifiers

    Abstract Purpose AIDs may disproportionately impact specific racial groups, but autoimmune (AID) prevalence information by minority racial group is sparse for many AIDs. The objective of this analysis was to supplement previously published AID prevalence rates by provid...

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  • publication . Article . Other literature type . 2015
    Restricted
    Authors:
    Henning Budde; Rolf Schwarz; Bruna Velasques; Pedro Ribeiro; Martin Holzweg; Sergio Machado; Marius Brazaitis; Felix Staack; Mirko Wegner;
    Publisher: Elsevier BV
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  • publication . Other literature type . Article . 2007
    Open Access English
    Authors:
    Steven P. Mathis; Venkatakrishna R. Jala; Bodduluri Haribabu;
    Persistent Identifiers

    Abstract The purpose of this review is to summarize the role that murine models of arthritis are playing in the understanding of human rheumatoid arthritis and how leukotriene B4 (LTB4) is emerging as an important target in this field. Both the collagen-induced arthriti...

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119 research outcomes, page 1 of 12