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79 research outcomes, page 1 of 8
  • publication . Other literature type . 2019
    Open Access
    Authors:
    AARC Consortium; AARC Community; Appint Members;
    Publisher: Zenodo
    Project: EC | AARC2 (730941)

    This document defines a generic browser-based protocol for conveying - to services - hints about the IdPs or IdP-SP-proxies that should be used for authenticating the principal. This protocol, colloquially referred to as Identity Provider (IdP) hinting, can greatly simp...

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  • publication . Article . 2020
    Open Access English
    Authors:
    C.O.S. Sorzano; F. de Isidro-Gomez; E. Fernández-Giménez; David Herreros; Sergio Marco; José María Carazo; C. Messaoudi;
    Project: EC | INSTRUCT-ULTRA (731005), EC | iNEXT-Discovery (871037), EC | EOSC-synergy (857647), EC | IMpaCT (857203), EC | EOSC-Life (824087), EC | HighResCells (810057), EC | CORBEL (654248)

    Electron tomography is a technique to obtain three-dimensional structural information of samples. However, the technique is limited by shifts occurring during acquisition that need to be corrected before the reconstruction process. In 2009, we proposed an approach for p...

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  • publication . Preprint . 2018
    Open Access English
    Authors:
    Argenzio, Elisabetta; Kedziora, Katarzyna M.; Nahidiazar, Leila; Isogai, Tadamoto; Perrakis, Anastassis; Jalink, Kees; Moolenaar, Wouter H.; Innocenti, Metello;
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | WENMR (261572), EC | West-Life (675858)

    AbstractCLIC4 is a cytosolic protein implicated in diverse actin-based processes, including integrin trafficking, cell adhesion and tubulogenesis. CLIC4 is rapidly recruited to the plasma membrane by G12/13-coupled receptor agonists and then partly co-localizes with β1 ...

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  • publication . Article . 2017
    Open Access
    Authors:
    van Zundert, G. C P; Trellet, M.; Schaarschmidt, J.; Kurkcuoglu Soner, Zeynep; David, M.; Verlato, M.; Rosato, A.; Bonvin, A. M J J; Sub NMR Spectroscopy; NMR Spectroscopy;
    Persistent Identifiers
    Publisher: Elsevier BV
    Countries: Italy, Netherlands
    Project: EC | BioExcel (675728), EC | West-Life (675858), EC | EGI-Engage (654142), EC | INDIGO-DataCloud (653549), NWO | Zooming into large assemb... (2300165908)

    Structure determination of complex molecular machines requires a combination of an increasing number of experimental methods with highly specialized software geared toward each data source to properly handle the gathered data. Recently, we introduced the two software pa...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Rodríguez-Arce, Irene; Al-Jubair, Tamim; Euba, Begoña; Fernández-Calvet, Ariadna; Gil-Campillo, Celia; Martí, Sara; Törnroth-Horsefield, Susanna; Riesbeck, Kristian; Garmendia, Junkal;
    Countries: Denmark, Spain
    Project: EC | WENMR (261572), EC | EOSC-hub (777536), EC | West-Life (675858)

    Nutrient iron sequestration is the most significant form of nutritional immunity and causes bacterial pathogens to evolve strategies of host iron scavenging. Cigarette smoking contains iron particulates altering lung and systemic iron homeostasis, which may enhance colo...

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  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Julie A. McMurry; Nick Juty; Niklas Blomberg; Tony Burdett; Tom Conlin; Nathalie Conte; Mélanie Courtot; John Deck; Michel Dumontier; Donal Fellows; ...
    Countries: Germany, Netherlands, United Kingdom, United Kingdom, United States, Denmark
    Project: EC | DDMORE (115156), NIH | Gene Ontology Consortium (5P41HG002273-08), EC | CORBEL (654248), NIH | UniProt: A centralized pr... (3U41HG007822-04S1), UKRI | Delivering ELIXIR-UK (BB/L005069/1), EC | BioExcel (675728), UKRI | DMMCore: Data and Model M... (BB/M013189/1), UKRI | CENTRE FOR SYNTHETIC BIOL... (BB/M017702/1), NIH | BioCADDIE: Biomedical and... (1U24AI117966-01), EC | ISBE (312455),...

    AbstractIn many disciplines, data is highly decentralized across thousands of online databases (repositories, registries, and knowledgebases). Wringing value from such databases depends on the discipline of data science and on the humble bricks and mortar that make inte...

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  • publication . Article . 2019
    Open Access
    Authors:
    Cerofolini, Linda; Giuntini, Stefano; Carlon, Azzurra; Ravera, Enrico; Calderone, Vito; Fragai, Marco; Parigi, Giacomo; Luchinat, Claudio;
    Persistent Identifiers
    Country: Italy
    Project: EC | West-Life (675858), EC | iNEXT (653706), EC | WENMR (261572)

    Resonance assignment and structural characterization of pharmacologically relevant proteins promise to improve understanding and safety of these proteins by rational design. However, the PEG coating that is used to evade the immune system also causes these molecules to ...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Young, Jasmine Y; Westbrook, John D; Feng, Zukang; Peisach, Ezra; Persikova, Irina; Sala, Raul; Sen, Sanchayita; Berrisford, John M; Swaminathan, G Jawahar; Oldfield, Thomas J; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: NIH | The BMRB as an evolving r... (3R01GM109046-01S1), NSF | PDB Management by the Res... (1338415), EC | West-Life (675858), WT , UKRI | Expanding the knowledge o... (BB/M011674/1), UKRI | The Electron Microscopy D... (BB/G022577/1), UKRI | CRESTANO - Common REst ap... (BB/K016970/1), UKRI | Validation of biomacromol... (BB/J007471/1), NIH | Unified Data Resource for... (5R01GM079429-05), NHMRC | Molecular control of cell... (104948),...

    Abstract The Protein Data Bank (PDB) is the single global repository for experimentally determined 3D structures of biological macromolecules and their complexes with ligands. The worldwide PDB (wwPDB) is the international collaboration that manages the PDB archive acco...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Gore, Swanand; Sanz García, Eduardo; Hendrickx, Pieter M.S.; Gutmanas, Aleksandras; Westbrook, John D.; Yang, Huanwang; Feng, Zukang; Baskaran, Kumaran; Berrisford, John M.; Hudson, Brian P.; ...
    Persistent Identifiers
    Project: EC | West-Life (675858), NSF | PDB Management by the Res... (1338415), UKRI | The Electron Microscopy D... (BB/G022577/1), WT , EC | BIOMEDBRIDGES (284209), WT | Protein Data Bank in Euro... (104948), UKRI | PDBHarvest - Harvesting m... (BB/M020428/1), UKRI | CRESTANO - Common REst ap... (BB/K016970/1), UKRI | Validation of biomacromol... (BB/J007471/1), UKRI | BioSolr: addressing the c... (BB/M013146/1),...

    Summary The Worldwide PDB recently launched a deposition, biocuration, and validation tool: OneDep. At various stages of OneDep data processing, validation reports for three-dimensional structures of biological macromolecules are produced. These reports are based on rec...

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  • publication . Other literature type . 2019
    Open Access English
    Authors:
    AARC Community members; AppInt members;
    Publisher: Zenodo
    Project: EC | AARC2 (730941)

    The AARC Blueprint Architecture (BPA) provides a set of building blocks for software architects and technical decision makers who are designing and implementing access management solutions for international research collaborations. This document describes the evolution ...

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79 research outcomes, page 1 of 8