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7,825 research outcomes, page 1 of 783
  • publication . Article . Other literature type . 2002
    Open Access
    Authors:
    Felix S F Ram; David Dm Brocklebank; John White; John Wright; Paul W. Jones;
    Persistent Identifiers
    Publisher: Wiley

    Background A number of different inhaler devices are available to deliver beta2-agonist bronchodilators in asthma. These include hydrofluoroalkane (HFA) or chlorofluorocarbon (CFC)-free propelled pressurised metered dose inhalers (pMDIs) and dry powder devices. Objectiv...

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  • publication . Other literature type . Article . 2008
    Open Access English
    Authors:
    Rory Johnson; Christina Hui‐Leng Teh; Hui Jia; Ravi Raj Vanisri; Tridansh Pandey; Zhong Hao Lu; Noel J. Buckley; Lawrence W. Stanton; Leonard Lipovich;
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory Press

    The essential transcriptional repressor REST (repressor element 1-silencing transcription factor) plays central roles in development and human disease by regulating a large cohort of neural genes. These have conventionally fallen into the class of known, protein-coding ...

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  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Forest Isbell; Andrew Gonzalez; M. Loreau; Jane Cowles; Sandra Díaz; Andy Hector; Georgina M. Mace; David A. Wardle; Mary I. O'Connor; J. Emmett Duffy; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | BIOSTASES (666971)

    Biodiversity enhances many of nature?s benefits to people, including the regulation of climate and the production of woodin forests, livestock forage in grasslands and fish in aquatic ecosystems. Yet people are now driving the sixth mass extinctionevent in Earth?s histo...

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  • publication . Other literature type . Article . 2015
    Open Access English
    Authors:
    Kristine Brown; Gustavo Chagoya; Shawn G. Kwatra; Timothy Yen; Stephen T. Keir; Mary Cooter; Katherine A. Hoadley; Ahmed Rasheed; Eric S. Lipp; Roger E. McLendon; ...
    Persistent Identifiers

    The development of drugs to inhibit glioblastoma (GBM) growth requires reliable pre-clinical models. To date, proteomic level validation of widely used patient-derived glioblastoma xenografts (PDGX) has not been performed. In the present study, we characterized 20 PDGX ...

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  • publication . Other literature type . Conference object . Preprint . 2019
    Open Access English
    Authors:
    Ruichu Cai; Zijian Li; Pengfei Wei; Jie Qiao; Kun Zhang; Zhifeng Hao;
    Persistent Identifiers
    Project: NIH | Administrative (5U54HG008540-02), NSF | Collaborative Research: C... (1829681), NIH | INTEGRATIVE GRAPHICAL MOD... (5R01LM012087-02)

    Domain adaptation is an important but challenging task. Most of the existing domain adaptation methods struggle to extract the domain-invariant representation on the feature space with entangling domain information and semantic information. Different from previous effor...

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  • publication . Other literature type . Article . 2003
    Open Access English
    Authors:
    Tze-Wey Loong;
    Publisher: BMJ Publishing Group Ltd.

    Can you explain why a test with 95% sensitivity might identify only 1% of affected people in the general population? The visual approach in this article should make the reason clearer I first encountered sensitivity and specificity in medical school. That is, I remember...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Biing Jiun Shen; Q. Fan; J. S. Huang; M. H. R. Ho; Wendy J. Mack; Howard N. Hodis;
    Publisher: Informa UK Limited

    PURPOSE: This study conducted confirmatory factor analysis (CFA) to examine the measurement structure of the Women’s Health Questionnaire (WHQ) and how its components were organized. METHODS: Participants were 448 postmenopausal women, with a mean age of 63.3 years. CFA...

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  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Selina Tingting Cheong; Tat Ming Ng; Keng Teng Tan;
    Persistent Identifiers
    Publisher: BMJ

    OBJECTIVES: Deprescribing can help reduce polypharmacy in the elderly and hospitalisation presents an opportunity to re-evaluate the use of medications. The aim of this study was to describe the drugs that were commonly suggested by pharmacists to be deprescribed in hos...

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  • publication . Other literature type . Article . 2018
    Open Access English
    Authors:
    Yibin Lin; R. N. V. Krishna Deepak; Johnathan Zixiang Zheng; Hao Fan; Lei Zheng;
    Persistent Identifiers
    Publisher: American Society for Biochemistry and Molecular Biology

    Lysophospholipid transporter (LplT) is a member of the major facilitator superfamily present in many Gram-negative bacteria. LplT catalyzes flipping of lysophospholipids (LPLs) across the bacterial inner membrane, playing an important role in bacterial membrane homeosta...

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  • publication . Other literature type . Article . 2007
    Open Access English
    Authors:
    Hongchuan Jin; Xian Wang; Jianming Ying; Ada Ho Yan Wong; Hongyu Li; Kwan Yeung Lee; Gopesh Srivastava; Anthony Tc Chan; Winnie Yeo; Brigette By Ma; ...
    Persistent Identifiers

    Tumor suppressor genes (TSGs) often locate at chromosomal regions with frequent deletions in tumors. Loss of 16q23 occurs frequently in multiple tumors, indicating the presence of critical TSGs at this locus, such as the well-studied WWOX. Herein, we found that ADAMTS18...

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7,825 research outcomes, page 1 of 783