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  • Restricted French
    Authors: 
    Ivaldi, Gilles;
    Publisher: HAL CCSD
    Country: France

    contribution à un site web; En dépit d’inquiétudes croissantes face aux conséquences économiques de la pandémie de coronavirus, la crise sanitaire ne semble pas alimenter pour l’heure le soutien aux partis de droite populiste tels que le Rassemblement national de Marine Le Pen en France, la Ligue italienne ou l’AfD en Allemagne. [Premier paragraphe]

  • Restricted English
    Authors: 
    Wunsch, Natasha;
    Countries: United Kingdom, France, France

    contribution à un site web; Several countries in the Western Balkans have responded to the Covid-19 outbreak with draconian measures that entail a further erosion of democracy, writes Natasha Wunsch. She argues the pandemic is shining a spotlight on the impact of geopolitical competition in the Western Balkans, where authoritarian forces are undermining the EU’s democracy promotion efforts.

  • Restricted French
    Authors: 
    Rouban, Luc;
    Country: France

    contribution à un site web; L’épidémie de coronavirus va poser des questions politiques de fond sur l’après-crise. Ces questions se posent sur plusieurs plans. [Premier paragraphe]

  • Restricted French
    Authors: 
    Mérieau, Eugénie;
    Country: France

    contribution à un site web; Quel régime politique est le plus efficace en temps de pandémie ? La comparaison entre « l’Occident démocratique » et « la Chine totalitaire » fait rage depuis le début de la crise sanitaire. Au risque de peser sur les décisions en matière de santé : le retard des démocraties occidentales dans la prise en compte du danger que représentait le Covid-19 peut ainsi être lié à l’incapacité de l’Occident à se penser en semblable de la Chine. Cette façon de penser a un nom : l’orientalisme.

  • Publication . Other literature type . 2020
    Restricted French
    Authors: 
    Ragot, Xavier;
    Publisher: HAL CCSD
    Country: France

    contribution à un site web; Les décisions prises dans l’urgence par les institutions économiques nationales et européennes seront-elles suffisantes pour amortir le choc de la crise économique, conséquence inévitable de la pandémie du Covid-19 ? Analyse par Xavier Ragot, président de l’Observatoire français des conjonctures économiques (OFCE), qui évoque aussi la nécessité de repenser, à l'issue de cet épisode tragique, les liens entre économie, société et environnement. [Premier paragraphe]

  • English
    Authors: 
    Frith, L, University of Manchester;
    Publisher: UK Data Service

    This study used a mixed method approach comprising of an online survey with public contributors involved in health and social care research; an online survey with public involvement professionals, those who are employed by organisations; and qualitative interviews with public contributors. We had 244 respondents to the public contributor survey and 65 for the public involvement professionals (PIPs) survey and conducted 22 qualitative interviews.This study has been prompted by the shift to non-face-to-face - remote - forms of working in patient public involvement and engagement (PPIE) brought on by Covid-19 prevention measures (such as social distancing). Working remotely includes using digital technologies such as: online conferencing software (Zoom, Microsoft Teams), emails, telephone calls and social media (WhatsApp, Facebook). Due to measures such as shielding and social distancing the usual ways of involving the public in research that included face-to-face meetings and events are not possible, and even with the eventual easing of lockdown, remote working is likely to continue. This creates particular challenges for ensuring access and engagement from all parts of society in health and social care research. There is a well-documented digital divide between those who use or have access to digital technologies and those who do not. This digital divide reflects the existing socio-economic inequalities, and PPIE that takes place remotely has the potential to further exclude already disadvantaged groups. This project aims to facilitate and improve ways of doing PPIE remotely and increase the diversity of public contributors involved in health and social care research. Our objectives are to: 1. Understand the barriers and facilitators to remote working, by: a. Exploring public contributors and PPIE professionals' experiences of remote PPIE. b. Exploring public contributors' preferences for different types of remote working. 2. Develop mechanisms for implementing improvements in remote working and ways to increase diversity in PPIE by: a. Conducting a rapid review of research and 'how to guides'. b. Develop training packages. We will recruit public contributors involved in research projects across the UK: the NIHR, charities, universities and other research organisations and people involved professionally with PPIE. This is a mixed-methods study with: surveys, qualitative interviews, and a discrete choice experiment. We will produce an analysis of how remote working in PPIE is affected by socio-economic and health inequalities, make recommendations for improving practice and develop training packages. The public contributor survey was comprised of tick box questions, Likert scale questions and open-ended questions where participants could enter free text responses. The survey asked general questions about role and PPIE experience, digital literacy and different aspects of remote working. We collected demographic information to enable us to draw conclusions from the data on how age, ethnicity, living arrangements and socio-economic status impact on participants use of remote communication tools. The survey ran from September to November 2020. For the survey for PPIE professionals, those who work in PPIE, organising PPIE activities, we developed the survey with input from our public contributors and PPIE professionals from the ARC NWC and the NIHR Research Design Service. Again, the development of this survey drew on our own experiences. We piloted the survey with members of the ARC team and public contributor (NT) to check for sense, consistency and readability. Like the PPIE contributor survey, the professional version was comprised of tick box questions, Likert scale questions, and open-ended questions for additional response. We asked what support and training they offered their public contributors; and any suggestions they had for improving remote working in PPIE. After the survey conducted with public contributors had closed, we purposively sample informants from key communities and conducted 22 semi-structured qualitative interviews with public contributors from across the UK. The topic guide was co-developed with the research team and public contributor (NT) from a preliminary analysis of the survey results and was designed to probe and explore the issues raised by the survey. The interviews were conducted via Zoom and audio reordered with the participant’s consent. The interviews were transcribed and then checked for accuracy and anonymised. The interviews last on average 60 minutes.

  • French
    Authors: 
    Dao, Lin-Lanh; Wang, Rui; Tan, Sun-Lay; Chuang, Ya-Han; Favelloz, Baptiste; Lacroix, Mathilda; VIGNY, Pierre-Jean; TICE-DSIRN, Unité; Ho, Christine;
    Publisher: HAL CCSD

    Fonds audiovisuel de l'Inalco, France, © 2021; En août 2016, le meurtre d'un couturier chinois à Aubervilliers provoquait des manifestations massives de la communauté asiatique de France. Ce drame avait mis en lumière les agressions physiques, mais aussi le racisme du quotidien subi par une population jugée "discrète, travailleuse et communautariste".Cette mobilisation, faisant écho à celle de 2010, a permis de donner une visibilité associative, médiatique et politique, à une communauté parfois oubliée des luttes anti-racistes des dernières décennies.Quatre ans plus tard, la pandémie du Covid-19 est venue replacer le racisme anti-asiatique dans le débat public. Aux titres de journaux racoleurs, se sont ajoutés des vexations du quotidien mais aussi des appels à "frapper chaque Chinois" sur les réseaux sociaux.Cette conférence aura pour but d'analyser les spécificités du racisme anti-asiatique en France et de cerner ses racines historiques, politiques et sociales. Nos intervenants, jeunes associatifs, journalistes et chercheurs, débattront également des moyens d'action pour faire avancer la lutte contre le racisme et les préjugés anti-asiatiques.

  • Other research product . Other ORP type . 2021
    Open Access German
    Authors: 
    Bolli, Thomas; id_orcid0000-0002-7317-6862; Caves, Katherine M.; Pusterla, Filippo; id_orcid0000-0003-3512-1462; Rageth, Ladina; id_orcid0000-0002-5431-0843; Renold, Ursula; id_orcid0000-0003-4196-0019; Sritharan, Aranya; Trachsel Díaz-Tejeiro, Sandra;
    Publisher: ETH Zürich, Professur für Bildungssysteme
    Country: Switzerland

    Im Rahmen des Forschungsprojekts LehrstellenPuls bietet dieses Informationsblatt einen Überblick über die Auswirkungen der COVID-19-Pandemie auf die berufliche Grundbildung in der Schweiz im Februar 2021 und vergleicht diese Ergebnisse mit der Situation in den Vormonaten von April 2020 bis Januar 2021.

  • English
    Authors: 
    White, Jonathan;
    Publisher: London School of Economics and Political Science
    Country: United Kingdom

    What is the future of technocracy, after COVID-19, asks Jonathan White (LSE)? Current crisis management only blurs ever more the boundary between politics and technical expertise, he argues.

  • Open Access English
    Authors: 
    Chatterjee, Maitrayee; Huang, Liane Z.X.; Wang, Chunyan; Mykytyn, Anna Z.; Westendorp, Bart; Wubbolts, Richard W.; Bosch, Berend-Jan; Haagmans, Bart L.; Putten, Jos P.M. van; Strijbis, Karin; +9 more
    Publisher: bioRxiv
    Country: Netherlands

    Mucins play an essential role in protecting the respiratory tract against microbial infections. The heavily O-glycosylated gel-forming mucins MUC5AC and MUC5B eliminate pathogens by mucociliary clearance while transmembrane mucins MUC1, MUC4, and MUC16 restrict microbial invasion at the apical surface of the epithelium. In this study, we determined the impact of host mucins and mucin glycans on SARS-CoV-2 spike-mediated epithelial entry. Human lung epithelial Calu-3 cells have endogenous expression of the SARS-CoV-2 entry receptor ACE2 and express high levels of glycosylated MUC1 on the surface but not MUC4 and MUC16. Removal of the MUC1 extracellular domain (ED) using the O-glycan-specific mucinase StcE greatly enhanced spike binding and viral infection. By contrast, removal of mucin glycans sialic acid and fucose did not impact viral invasion. This study implicates the glycosylated ED of MUC1 as an important component of the host defense that restricts the severity of SARS-CoV-2 infection.

Advanced search in
Research products
arrow_drop_down
Searching FieldsTerms
Any field
arrow_drop_down
includes
arrow_drop_down
Include:
9,021 Research products, page 1 of 903
  • Restricted French
    Authors: 
    Ivaldi, Gilles;
    Publisher: HAL CCSD
    Country: France

    contribution à un site web; En dépit d’inquiétudes croissantes face aux conséquences économiques de la pandémie de coronavirus, la crise sanitaire ne semble pas alimenter pour l’heure le soutien aux partis de droite populiste tels que le Rassemblement national de Marine Le Pen en France, la Ligue italienne ou l’AfD en Allemagne. [Premier paragraphe]

  • Restricted English
    Authors: 
    Wunsch, Natasha;
    Countries: United Kingdom, France, France

    contribution à un site web; Several countries in the Western Balkans have responded to the Covid-19 outbreak with draconian measures that entail a further erosion of democracy, writes Natasha Wunsch. She argues the pandemic is shining a spotlight on the impact of geopolitical competition in the Western Balkans, where authoritarian forces are undermining the EU’s democracy promotion efforts.

  • Restricted French
    Authors: 
    Rouban, Luc;
    Country: France

    contribution à un site web; L’épidémie de coronavirus va poser des questions politiques de fond sur l’après-crise. Ces questions se posent sur plusieurs plans. [Premier paragraphe]

  • Restricted French
    Authors: 
    Mérieau, Eugénie;
    Country: France

    contribution à un site web; Quel régime politique est le plus efficace en temps de pandémie ? La comparaison entre « l’Occident démocratique » et « la Chine totalitaire » fait rage depuis le début de la crise sanitaire. Au risque de peser sur les décisions en matière de santé : le retard des démocraties occidentales dans la prise en compte du danger que représentait le Covid-19 peut ainsi être lié à l’incapacité de l’Occident à se penser en semblable de la Chine. Cette façon de penser a un nom : l’orientalisme.

  • Publication . Other literature type . 2020
    Restricted French
    Authors: 
    Ragot, Xavier;
    Publisher: HAL CCSD
    Country: France

    contribution à un site web; Les décisions prises dans l’urgence par les institutions économiques nationales et européennes seront-elles suffisantes pour amortir le choc de la crise économique, conséquence inévitable de la pandémie du Covid-19 ? Analyse par Xavier Ragot, président de l’Observatoire français des conjonctures économiques (OFCE), qui évoque aussi la nécessité de repenser, à l'issue de cet épisode tragique, les liens entre économie, société et environnement. [Premier paragraphe]

  • English
    Authors: 
    Frith, L, University of Manchester;
    Publisher: UK Data Service

    This study used a mixed method approach comprising of an online survey with public contributors involved in health and social care research; an online survey with public involvement professionals, those who are employed by organisations; and qualitative interviews with public contributors. We had 244 respondents to the public contributor survey and 65 for the public involvement professionals (PIPs) survey and conducted 22 qualitative interviews.This study has been prompted by the shift to non-face-to-face - remote - forms of working in patient public involvement and engagement (PPIE) brought on by Covid-19 prevention measures (such as social distancing). Working remotely includes using digital technologies such as: online conferencing software (Zoom, Microsoft Teams), emails, telephone calls and social media (WhatsApp, Facebook). Due to measures such as shielding and social distancing the usual ways of involving the public in research that included face-to-face meetings and events are not possible, and even with the eventual easing of lockdown, remote working is likely to continue. This creates particular challenges for ensuring access and engagement from all parts of society in health and social care research. There is a well-documented digital divide between those who use or have access to digital technologies and those who do not. This digital divide reflects the existing socio-economic inequalities, and PPIE that takes place remotely has the potential to further exclude already disadvantaged groups. This project aims to facilitate and improve ways of doing PPIE remotely and increase the diversity of public contributors involved in health and social care research. Our objectives are to: 1. Understand the barriers and facilitators to remote working, by: a. Exploring public contributors and PPIE professionals' experiences of remote PPIE. b. Exploring public contributors' preferences for different types of remote working. 2. Develop mechanisms for implementing improvements in remote working and ways to increase diversity in PPIE by: a. Conducting a rapid review of research and 'how to guides'. b. Develop training packages. We will recruit public contributors involved in research projects across the UK: the NIHR, charities, universities and other research organisations and people involved professionally with PPIE. This is a mixed-methods study with: surveys, qualitative interviews, and a discrete choice experiment. We will produce an analysis of how remote working in PPIE is affected by socio-economic and health inequalities, make recommendations for improving practice and develop training packages. The public contributor survey was comprised of tick box questions, Likert scale questions and open-ended questions where participants could enter free text responses. The survey asked general questions about role and PPIE experience, digital literacy and different aspects of remote working. We collected demographic information to enable us to draw conclusions from the data on how age, ethnicity, living arrangements and socio-economic status impact on participants use of remote communication tools. The survey ran from September to November 2020. For the survey for PPIE professionals, those who work in PPIE, organising PPIE activities, we developed the survey with input from our public contributors and PPIE professionals from the ARC NWC and the NIHR Research Design Service. Again, the development of this survey drew on our own experiences. We piloted the survey with members of the ARC team and public contributor (NT) to check for sense, consistency and readability. Like the PPIE contributor survey, the professional version was comprised of tick box questions, Likert scale questions, and open-ended questions for additional response. We asked what support and training they offered their public contributors; and any suggestions they had for improving remote working in PPIE. After the survey conducted with public contributors had closed, we purposively sample informants from key communities and conducted 22 semi-structured qualitative interviews with public contributors from across the UK. The topic guide was co-developed with the research team and public contributor (NT) from a preliminary analysis of the survey results and was designed to probe and explore the issues raised by the survey. The interviews were conducted via Zoom and audio reordered with the participant’s consent. The interviews were transcribed and then checked for accuracy and anonymised. The interviews last on average 60 minutes.

  • French
    Authors: 
    Dao, Lin-Lanh; Wang, Rui; Tan, Sun-Lay; Chuang, Ya-Han; Favelloz, Baptiste; Lacroix, Mathilda; VIGNY, Pierre-Jean; TICE-DSIRN, Unité; Ho, Christine;
    Publisher: HAL CCSD

    Fonds audiovisuel de l'Inalco, France, © 2021; En août 2016, le meurtre d'un couturier chinois à Aubervilliers provoquait des manifestations massives de la communauté asiatique de France. Ce drame avait mis en lumière les agressions physiques, mais aussi le racisme du quotidien subi par une population jugée "discrète, travailleuse et communautariste".Cette mobilisation, faisant écho à celle de 2010, a permis de donner une visibilité associative, médiatique et politique, à une communauté parfois oubliée des luttes anti-racistes des dernières décennies.Quatre ans plus tard, la pandémie du Covid-19 est venue replacer le racisme anti-asiatique dans le débat public. Aux titres de journaux racoleurs, se sont ajoutés des vexations du quotidien mais aussi des appels à "frapper chaque Chinois" sur les réseaux sociaux.Cette conférence aura pour but d'analyser les spécificités du racisme anti-asiatique en France et de cerner ses racines historiques, politiques et sociales. Nos intervenants, jeunes associatifs, journalistes et chercheurs, débattront également des moyens d'action pour faire avancer la lutte contre le racisme et les préjugés anti-asiatiques.

  • Other research product . Other ORP type . 2021
    Open Access German
    Authors: 
    Bolli, Thomas; id_orcid0000-0002-7317-6862; Caves, Katherine M.; Pusterla, Filippo; id_orcid0000-0003-3512-1462; Rageth, Ladina; id_orcid0000-0002-5431-0843; Renold, Ursula; id_orcid0000-0003-4196-0019; Sritharan, Aranya; Trachsel Díaz-Tejeiro, Sandra;
    Publisher: ETH Zürich, Professur für Bildungssysteme
    Country: Switzerland

    Im Rahmen des Forschungsprojekts LehrstellenPuls bietet dieses Informationsblatt einen Überblick über die Auswirkungen der COVID-19-Pandemie auf die berufliche Grundbildung in der Schweiz im Februar 2021 und vergleicht diese Ergebnisse mit der Situation in den Vormonaten von April 2020 bis Januar 2021.

  • English
    Authors: 
    White, Jonathan;
    Publisher: London School of Economics and Political Science
    Country: United Kingdom

    What is the future of technocracy, after COVID-19, asks Jonathan White (LSE)? Current crisis management only blurs ever more the boundary between politics and technical expertise, he argues.

  • Open Access English
    Authors: 
    Chatterjee, Maitrayee; Huang, Liane Z.X.; Wang, Chunyan; Mykytyn, Anna Z.; Westendorp, Bart; Wubbolts, Richard W.; Bosch, Berend-Jan; Haagmans, Bart L.; Putten, Jos P.M. van; Strijbis, Karin; +9 more
    Publisher: bioRxiv
    Country: Netherlands

    Mucins play an essential role in protecting the respiratory tract against microbial infections. The heavily O-glycosylated gel-forming mucins MUC5AC and MUC5B eliminate pathogens by mucociliary clearance while transmembrane mucins MUC1, MUC4, and MUC16 restrict microbial invasion at the apical surface of the epithelium. In this study, we determined the impact of host mucins and mucin glycans on SARS-CoV-2 spike-mediated epithelial entry. Human lung epithelial Calu-3 cells have endogenous expression of the SARS-CoV-2 entry receptor ACE2 and express high levels of glycosylated MUC1 on the surface but not MUC4 and MUC16. Removal of the MUC1 extracellular domain (ED) using the O-glycan-specific mucinase StcE greatly enhanced spike binding and viral infection. By contrast, removal of mucin glycans sialic acid and fucose did not impact viral invasion. This study implicates the glycosylated ED of MUC1 as an important component of the host defense that restricts the severity of SARS-CoV-2 infection.

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