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1,523 research outcomes, page 1 of 153
  • publication . Other literature type . Article . 2018
    Open Access English
    Authors:
    Atherton, Christopher John; Barton, Thomas; Basney, Jim; Broeder, Daan; Costa, Alessandro; Daalen, Mirjam Van; Dyke, Stephanie; Elbers, Willem; Enell, Carl-Fredrik; Fasanelli, Enrico Maria Vincenzo; ...
    Project: EC | GN4-2 (731122), EC | IS-ENES (228203), EC | AARC2 (730941), EC | ELIXIR-EXCELERATE (676559), EC | IS-ENES2 (312979), EC | CORBEL (654248), EC | CALIPSOplus (730872)

    This white-paper expresses common requirements of Research Communities seeking to leverage Identity Federation for Authentication and Authorisation. Recommendations are made to Stakeholders to guide the future evolution of Federated Identity Management in a direction th...

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  • publication . Preprint . Other literature type . Article . 2019
    Open Access English
    Authors:
    Lloyd-Jones, Luke R.; Zeng, Jian; Sidorenko, Julia; Yengo, Loïc; Moser, Gerhard; Kemper, Kathryn E.; Wang, Huanwei; Zheng, Zhili; Magi, Reedik; Esko, Tõnu; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NHMRC | Advanced whole-genome app... (1080157), NIH | Institute for Clinical an... (3UL1RR025005-03S2), EC | ENGAGE (201413), NIH | Analysis of Genome-Wide D... (5R01AG042568-03), EC | ADOPT BBMRI-ERIC (676550), EC | CORBEL (654248), NIH | Creating a National Resou... (5RC2AG036495-02), NIH | Expanding a National Reso... (3RC4AG039029-01S1), NHMRC | Neurogenetics and Statist... (1078037), NHMRC | Complex trait genomics (1113400),...

    Accurate prediction of an individual’s phenotype from their DNA sequence is one of the great promises of genomics and precision medicine. We extend a powerful individual-level data Bayesian multiple regression model (BayesR) to one that utilises summary statistics from ...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Medve, Laura; Achilli, Silvia; Guzman‐Caldentey, Joan; Thépaut, Michel; Senaldi, Luca; Le Roy, Aline; Sattin, Sara; Ebel, Christine; Vivès, Corinne; Martin‐Santamaria, Sonsoles; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | IMMUNOSHAPE (642870)

    Abstract Chemical modification of pseudo‐dimannoside ligands guided by fragment‐based design allowed for the exploitation of an ammonium‐binding region in the vicinity of the mannose‐binding site of DC‐SIGN, leading to the synthesis of a glycomimetic antagonist (compoun...

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  • publication . Article . Conference object . Other literature type . 2018
    Open Access English
    Authors:
    Sanz-Murillo, Marta; Xu, Jun; Belogurov, Georgiy A.; Calvo, Olga; Gil-Carton, David; Moreno-Morcillo, María; Wang, Dong; Fernández-Tornero, Carlos;
    Project: EC | iNEXT (653706)

    Peer reviewed

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  • publication . Article . 2016
    Open Access
    Authors:
    Zander, Ulrich; Hoffmann, Guillaume; Cornaciu, Irina; Marquette, Jean-Pierre; Papp, Gergely; Landret, Christophe; Seroul, Gaël; Sinoir, Jérémy; Röwer, Martin; Felisaz, Frank; ...
    Persistent Identifiers
    Publisher: International Union of Crystallography (IUCr)
    Project: EC | iNEXT (653706), EC | BIOSTRUCT-X (283570)

    New methods for crystal mounting, soaking and cryocooling contribute to bridging the automation gap between crystallization and X-ray data collection.

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  • publication . Article . 2013
    Open Access English
    Authors:
    Paradzik, Tina; Ivic, Nives; Filic, Zelimira; Manjasetty, Babu A.; Herron, Paul; Luic, Marija; Vujaklija, Dusica;
    Persistent Identifiers
    Project: MZOS | Fundamental molecular stu... (098-0982913-2877), MZOS | Protein-ligand interactio... (098-1191344-2943), EC | BIOSTRUCT-X (283570)

    The linear chromosome of Streptomyces coelicolor contains two paralogous ssb genes, ssbA and ssbB. Following mutational analysis, we concluded that ssbA is essential, whereas ssbB plays a key role in chromosome segregation during sporulation. In the ssbB mutant, ∼30% of...

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  • publication . Article . 2013
    Open Access
    Authors:
    Aleksandras Gutmanas; Younes Alhroub; Gary M. Battle; John M. Berrisford; Estelle Bochet; Matthew J. Conroy; Jose M. Dana; Manuel A. Fernandez Montecelo; Glen van Ginkel; Swanand P. Gore; ...
    Persistent Identifiers
    Project: WT | Protein Data Bank in Euro... (088944), UKRI | GENOME-3D: a UK network p... (BB/I02576X/1), EC | BIOMEDBRIDGES (284209), NIH | Unified Data Resource for... (5R01GM079429-05), UKRI | Validation of biomacromol... (BB/J007471/1), UKRI | CRESTANO - Common REst ap... (BB/K016970/1)

    The Protein Data Bank in Europe (pdbe.org) is a founding member of the Worldwide PDB consortium (wwPDB; wwpdb.org) and as such is actively engaged in the deposition, annotation, remediation and dissemination of macromolecular structure data through the single global arc...

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  • publication . Article . 2016
    Open Access
    Authors:
    Svirskaitė, Julija; Oksanen, Hanna M.; Daugelavičius, Rimantas; Bamford, Dennis H.;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: AKA | Finnish participation in ... (272853)

    The slow rate of adsorption and non-synchronous release of some archaeal viruses have hindered more thorough analyses of the mechanisms of archaeal virus release. To address this deficit, we utilized four viruses that infect Haloarcula hispanica that represent the four ...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Schulte, Tim; Löfling, Jonas; Mikaelsson, Cecilia; Kikhney, Alexey; Hentrich, Karina; Diamante, Aurora; Ebel, Christine; Normark, Staffan; Svergun, Dmitri; Henriques-Normark, Birgitta; ...
    Persistent Identifiers
    Publisher: Royal Society Publishing
    Project: EC | BIOSTRUCT-X (283570)

    Streptococcus pneumoniae is a major human pathogen, and a leading cause of disease and death worldwide. Pneumococcal invasive disease is triggered by initial asymptomatic colonization of the human upper respiratory tract. The pneumococcal serine-rich repeat protein (Ps...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Sforzi, Jacopo; Ferrauto, Giuseppe; Aime, Silvio; Geninatti Crich, Simonetta;
    Persistent Identifiers
    Publisher: American Chemical Society
    Project: EC | CORBEL (654248)

    Open in a separate window The development of an innovative and easy way to run assays for the quantitative detection of DNA present in biological fluids (i.e., blood, urine, and saliva) is of great interest for early diagnosis (e.g., tumors) and personalized medicine. H...

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1,523 research outcomes, page 1 of 153