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28,292 research outcomes, page 1 of 2,830
  • publication . Article . 2005
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    Authors:
    Betty H. Johnson; Leland L. Smith;
    Persistent Identifiers
    Publisher: Elsevier BV

    In view of hypotheses suggesting mutagenesis is implicated in atherosclerosis, a total of 18 lipid extracts of human aortal tissues was examined by the standard Ames mutagenicity bioassay using Salmonella typhimurium or by a liquid modification thereof. One lipid extrac...

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  • publication . Article . 2006
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    Authors:
    G. Subramanyam; J. Vijaya; D. Peramma; V. Jayaram; D. Ramesh Babu; M.V. Ramakrishna;
    Persistent Identifiers
    Publisher: Elsevier BV
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  • publication . Article . 2005
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    Authors:
    K.N. Bretherton; Allan J. Day; Sandford L. Skinner;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Entry of 125 I-labelled low density lipoprotein ([ 125 I]LDL) into the aortic intima was studied over 6 hours in normotensive and hypertensive rabbits fed a 1% cholesterol diet for 9 and 4 weeks respectively. Studies were also made in hypertensive and normotens...

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  • publication . Article . 2015
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    Authors:
    Niku Oksala; Jenita Pärssinen; Ilkka Seppälä; Norman Klopp; Thomas Illig; Reijo Laaksonen; Mari Levula; Emma Raitoharju; Ivana Kholová; Thanos Sioris; ...
    Publisher: Elsevier BV
    Project: AKA | Life-long stability and h... (286284)

    Abstract Background Kindlins (FERMT) are cytoplasmic proteins required for integrin (ITG) activation, leukocyte transmigration, platelet aggregation and thrombosis. Characterization of kindlins and their association with atherosclerotic plaques in human(s) is lacking. M...

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  • publication . Article . Other literature type . 2019
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    Authors:
    Feng-Hua Wang; Jing Liu; Qiuju Deng; Yue Qi; Miao Wang; Ying Wang; Xingguang Zhang; Dong Zhao;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Background and aims The association between amino acids and small dense low-density lipoprotein cholesterol (sdLDL-C) and remnant-like particle cholesterol (RLP-C) remains poorly understood. This study aims to investigate the association between plasma essentia...

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  • publication . Article . Other literature type . 1993
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    Authors:
    E L Filonzi; Hans Zoellner; Heather Stanton; John A. Hamilton;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Smooth muscle cells (SMC) are the major cell type found in the walls of large blood vessels and appear to participate in local immune and inflammatory reactions, as well as in certain vascular diseases. We tested whether human arterial SMC can produce in vitro ...

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  • publication . Article . Other literature type . 2013
    Open Access
    Authors:
    Amanda J. Cox; Maggie C.Y. Ng; Jianzhao Xu; Carl D. Langefeld; Kenneth L. Koch; Paul A. Dawson; J. Jeffrey Carr; Barry I. Freedman; Fang-Chi Hsu; Donald W. Bowden;
    Publisher: Elsevier BV

    Objective A negative relationship between total bilirubin concentration (TBili) and CVD risk has been documented in a series of epidemiological studies. In addition, TBili is thought to be under strong genetic regulation via the UGT1A gene family, suggesting it may be a...

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  • publication . Other literature type . Article . 2012
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    Authors:
    Doralisa Morrone; William S. Weintraub; Peter P. Toth; Mary E. Hanson; Robert S. Lowe; Jianxin Lin; Arvind Shah; Andrew M. Tershakovec;
    Persistent Identifiers
    Publisher: Elsevier BV

    Objective: Patients with dyslipoproteinemia constitute the largest risk group for development of atherosclerosis and cardiovascular disease (CVD). Despite extensive statin use, many patients with CVD risk do not achieve guideline-recommended low-density lipoprotein chol...

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  • publication . Article . Other literature type . 2008
    Open Access
    Authors:
    Nena Aleksic; Yao Wei W Wang; Chul Ahn; Harinder S. Juneja; Aaron R. Folsom; Kenneth K. Wu;
    Publisher: Elsevier BV

    Objective Prospective studies have reported a positive association of coagulation factors with risk of coronary heart disease (CHD). It is unclear whether these coagulation factors interact.

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  • publication . Article . 2015
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    Authors:
    Manabu Niimi; Dongshan Yang; Shuji Kitajima; Bo Ning; Chuan Wang; Shen Li; Enqi Liu; Jifeng Zhang; Y. Eugene Chen; Jianglin Fan;
    Persistent Identifiers
    Publisher: Elsevier BV

    Abstract Objective Rabbits are one of the best animal models for the study of hyperlipidemia and atherosclerosis. Although many transgenic rabbits have been created, the development of gene knockout (KO) rabbits has been impossible due to the lack of rabbit embryonic st...

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28,292 research outcomes, page 1 of 2,830