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153,118 research outcomes, page 1 of 15,312
  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Hossein-Ardeschir Ghofrani; Miguel-Angel Gomez Sanchez; Marc Humbert; David Pittrow; Gérald Simonneau; Henning Gall; Ekkehard Grünig; Hans Klose; Michael Halank; David Langleben; ...

    OBJECTIVE: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase 3 random...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Anders, K.; Lindenbergh, R.C.; Vos, S.E.; Mara, H.; de Vries, S.; Höfle, B.;
    Project: EC | NEMO (291206)

    Geomorphic processes occur spatially variable and at varying magnitudes, frequencies and velocities, which poses a great challenge to current methods of topographic change analysis. For the quantification of surface change, permanent terrestrial laser scanning (TLS) can...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Aurelie Schwartzentruber; Camilla Boschian; Fernanda Martins Lopes; Monika A Myszczynska; Elizabeth J. New; Julien Beyrath; Jan A.M. Smeitink; Laura Ferraiuolo; Heather Mortiboys;
    Publisher: Nature Publishing Group
    Project: WT , ARC | Discovery Projects - Gran... (DP180101897)

    AbstractMutations inPRKNare the most common cause of early onset Parkinson’s disease. Parkin is an E3 ubiquitin ligase, functioning in mitophagy. Mitochondrial abnormalities are present inPRKNmutant models. Patient derived neurons are a promising model in which to study...

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  • publication . Other literature type . 2021
    Open Access
    Authors:
    Parodi, Alejandro; Leip, Adrian; Boer, de, Imke; Siegers, Petronella M.; Ziegler, Friederike; Temme, Liesbeth; Herrero, Mario; Tuomisto, Hanna; Valin, Hugo; Middelaar, van, Corina; ...

    Contains data and R code for analysis and visualizations of the study The potential of future foods for sustainable and healthy diets

  • publication . Other literature type . Article . 2017
    Open Access English
    Authors:
    Pappas, Maria L; Broekgaarden, Colette; Broufas, George D; Kant, Merijn R; Messelink, Gerben J; Steppuhn, Anke; Wäckers, Felix; van Dam, Nicole M;
    Project: NWO | Outsmarting the attacker:... (2300180196), NWO | Characterization of tomat... (2300179605)

    Abstract Biological control is an important ecosystem service delivered by natural enemies. Together with breeding for plant defence, it constitutes one of the most promising alternatives to pesticides for controlling herbivores in sustainable crop production. Especiall...

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  • publication . Article . Review . Other literature type . 2017
    Open Access
    Authors:
    Sara De Matteis; Dick Heederik; Alex Burdorf; Claudio Colosio; Paul Cullinan; Paul K. Henneberger; Ann Olsson; Anne Raynal; Jos Rooijackers; Tiina Santonen; ...
    Publisher: European Respiratory Society

    Occupational lung diseases are an important public health issue and are avoidable through preventive interventions in the workplace. Up-to-date knowledge about changes in exposure to occupational hazards as a result of technological and industrial developments is essent...

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  • publication . Other literature type . 2017
    Closed Access English
    Authors:
    Tromp, J; Steggink, L. C.; Van Veldhuisen, D. J.; Gietema, J. A.; van der Meer, P.;

    Treatment for cancer has improved in the last decades, resulting in a significantly reduced morbidity and mortality. 1-3 Unfortunately, many systemic treatment options are associated with an increased risk of adverse cardiac effects. 4 These adverse cardiac effects have...

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  • publication . Article . Other literature type . 2009
    Open Access
    Authors:
    Xifeng Wu; Yuanqing Ye; Lambertus A. Kiemeney; Patrick Sulem; Thorunn Rafnar; Giuseppe Matullo; Daniela Seminara; Teruhiko Yoshida; Norihisa Saeki; Angeline S. Andrew; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    We conducted a genome-wide association study on 969 bladder cancer cases and 957 controls from Texas. For fast-track validation, we evaluated 60 SNPs in three additional US populations and validated the top SNP in nine European populations. A missense variant (rs2294008...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Cécile R. L. Boot; Micky Scharn; Allard J. van der Beek; Lars L. Andersen; Chris Elbers; Maarten Lindeboom;
    Persistent Identifiers
    Publisher: Multidisciplinary Digital Publishing Institute

    3.2%). Thus, while ambitious pension reforms can benefit labor supply, the adverse effects should be considered, especially because other studies have shown a link between unemployment and poor health.

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153,118 research outcomes, page 1 of 15,312