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72,360 research outcomes, page 1 of 7,236
  • publication . Article . Other literature type . 2013
    Open Access
    Authors:
    Sylvan C. Baca; Davide Prandi; Michael S. Lawrence; Juan Miguel Mosquera; Alessandro Romanel; Yotam Drier; Kyung Park; Naoki Kitabayashi; Theresa Y. MacDonald; Mahmoud Ghandi; ...
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: NIH | SPORE in Prostate Cancer (5P50CA090381-05), SNSF | Functional Role of SPOP P... (PASMP3_145764), NIH | Defining Melanoma Therape... (1DP2OD002750-01), NIH | MEDICAL SCIENTISTS (5T32GM007753-07), NIH | A Systems Biology Approac... (2U01CA111275-06), NIH | Large Scale Sequencing an... (3U54HG003067-07S1)

    The analysis of exonic DNA from prostate cancers has identified recurrently mutated genes, but the spectrum of genome-wide alterations has not been profiled extensively in this disease. We sequenced the genomes of 57 prostate tumors and matched normal tissues to charact...

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  • publication . Article . Other literature type . 2009
    Open Access
    Authors:
    Silvia Miano; Maria PiaVilla; Dora Blanco; Elena Zamora; Rosa Rodriguez; Raffaele Ferri; Oliviero Bruni; Rosa Peraita-Adrados;
    Persistent Identifiers

    AGE IS THE MOST IMPORTANT PHYSIOLOGIC FACTOR MODULATING HUMAN SLEEP AND ALSO INFLUENCES THE ELECTROENCEPHALOGRAPHIC (EEG) PATTERNS and contributes to the occurrence and features of arousals. Arousal can be considered as a short transient intrusion of wakefulness EEG rhy...

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  • publication . Other literature type . Article . 1997
    Open Access English
    Authors:
    L. De Franceschi; Laura Fumagalli; Oliviero Olivieri; R. Corrocher; Clifford A. Lowell; Giorgio Berton;
    Persistent Identifiers

    Src-family kinases play a central role in regulation of hematopoietic cell functions. We found that mouse erythrocytes express the Src-family kinases Fgr and Hck, as well as Lyn. To directly test whether Fgr and Hck play any role in erythrocyte function, we analyzed red...

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  • publication . Article . 2007
    Open Access English
    Authors:
    Jan Andersson; Åsa M. Sjögren; David S. Horner; Colleen A. Murphy; Patricia Dyal; Staffan G. Svärd; John M. Logsdon; Mark A. Ragan; Robert P. Hirt; Andrew J. Roger;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: CIHR

    Abstract Background Comparative genomic studies of the mitochondrion-lacking protist group Diplomonadida (diplomonads) has been lacking, although Giardia lamblia has been intensively studied. We have performed a sequence survey project resulting in 2341 expressed sequen...

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  • publication . Article . Other literature type . 2008
    Open Access
    Authors:
    Sophie Martin; Riccardo Rodolfo-Metalpa; Emma Ransome; Sonia J. Rowley; Maria-Christina Buia; Jean-Pierre Gattuso; Jason M. Hall-Spencer;
    Persistent Identifiers
    Publisher: The Royal Society

    Surface ocean pH is likely to decrease by up to 0.4 units by 2100 due to the uptake of anthropogenic CO 2 from the atmosphere. Short-term experiments have revealed that this degree of seawater acidification can alter calcification rates in certain planktonic and benthi...

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  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Paolo Gelosa; Davide Lecca; Marta Fumagalli; Dorota Wypych; Alice Pignieri; Mauro Cimino; Claudia Verderio; Malin Enerbäck; Elham Nikookhesal; Elena Tremoli; ...
    Persistent Identifiers

    The ADP-responsive P2Y12 receptor is expressed on both platelets and microglia. Clinical data show that ticagrelor, a direct-acting, reversibly binding P2Y12-receptor antagonist, reduces total cardiovascular events, including stroke. In our present study, we investigat...

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  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    Simone Ferrero; Valerio Gaetano Vellone; Fabio Barra;
    Persistent Identifiers
    Publisher: AME Publishing Company

    Endometriosis is a chronic disease characterized by the presence of hormone-responsive endometriotic glands and stroma outside the uterus that affect at least 4% of reproductive age women (1). It may be asymptomatic, but it frequently causes pain symptoms that negative ...

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  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Julian H. Krolik; Philip J. Armitage; Yanfei Jiang; Giuseppe Lodato;
    Persistent Identifiers
    Publisher: Springer
    Project: NSF | Physics of Tidal Disrupti... (1715032), NSF | Kavli Institute for Theor... (1748958)

    Comment: A chapter in the ISSI review book "The Tidal Disruption of Stars by Massive Black Holes", to be published in Space Science Reviews

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  • publication . Article . Other literature type . 2004
    Open Access
    Authors:
    R de Marco; Simone Accordini; I Cerveri; Angelo Corsico; Jordi Sunyer; Françoise Neukirch; Nino Künzli; Bénédicte Leynaert; Christer Janson; Thorarinn Gislason; ...
    Persistent Identifiers
    Publisher: BMJ

    Background: The recently published GOLD guidelines provide a new system for staging chronic obstructive pulmonary disease (COPD) from mild (stage I) to very severe (stage IV) and introduce a stage 0 (chronic cough and phlegm without airflow obstruction) that includes su...

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  • publication . Article . Other literature type . 1989
    Open Access
    Authors:
    G Melucci-Vigo; C Ciotta; G Risuleo;
    Publisher: American Society for Microbiology

    A deletion in the polyomavirus late region results in a drastic reduction of viral replication, as shown after transfection of viral DNA into 3T6 cells. This mutation is cis acting, since cotransfection with wild-type DNA did not restore the normal phenotype. Viral DNA ...

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72,360 research outcomes, page 1 of 7,236