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  • PRONKJEWAIL

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  • Open Access English
    Authors: 
    Märtson, Anne-Grete; Veringa, Anette; van den Heuvel, Edwin R; Bakker, Martijn; Touw, Daan; van der Werf, Tjip S; Span, Lambert F R; Alffenaar, Jan-Willem C;
    Project: EC | PRONKJEWAIL (713660)

    Posaconazole is indicated for prophylaxis and treatment of invasive aspergillosis. Therapeutic drug monitoring (TDM) of posaconazole is used to optimise drug exposure. The aim of this study was to analyse and describe the TDM practices and exposure of posaconazole table...

  • Other research product . Other ORP type . 2017
    Open Access English
    Authors: 
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), EC | PRONKJEWAIL (713660)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

  • Other research product . Other ORP type . 2018
    Open Access English
    Authors: 
    van Beek, Nienke; Klionsky, Daniel J; Reggiori, Fulvio;
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), EC | DRIVE (765912)

    The catabolic process of macroautophagy, through the rapid degradation of unwanted cellular components, is involved in a multitude of cellular and organismal functions that are essential to maintain homeostasis. Those functions include adaptation to starvation, cell dev...