Quick search
Advanced search in
Field to searchTerm
Add rule
Filters (3)
Download Results
388 research outcomes, page 1 of 39
  • publication . Article . Other literature type . Preprint . 2021
    Open Access English
    Authors:
    Maryam Alqabandi; N. de Franceschi; Nolwenn Miguet; Sourav Maity; Marta Bally; Wouter H. Roos; Winfried Weissenhorn; Patricia Bassereau; Stéphanie Mangenot;
    Project: ANR | PSL (ANR-10-IDEX-0001), EC | ESCRT model (751715), ANR | ESCRTfission (ANR-14-CE09-0003), EC | INTERACT (751404), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Abstract Background ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast. In humans, ESCRT-III CHMP2 exists as two isoforms, CHMP2A and CHMP2B, but their physical characteristics have...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Clarisse Uwizeye; Johan Decelle; Pierre-Henri Jouneau; Serena Flori; Benoit Gallet; Jean-Baptiste Keck; Davide Dal Bo; Christine Moriscot; Claire Seydoux; Fabien Chevalier; ...
    Publisher: HAL CCSD
    Project: EC | ChloroMito (833184), ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | CORBEL (654248), ANR | MoMix (ANR-17-CE05-0029)

    Nature Communications, 12 (1)

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Ohmann, Christian; Moher, David; Siebert, Maximilian; Motschall, Edith; Naudet, Florian;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | CORBEL (654248)

    ObjectivesTo explore the impact of data-sharing initiatives on the intent to share data, on actual data sharing, on the use of shared data and on research output and impact of shared data.Eligibility criteriaAll studies investigating data-sharing practices for individua...

    Add to ORCIDorcid
  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Uwizeye Clarisse; Mars Brisbin Margaret; Gallet Benoit; Chevalier Fabien; LeKieffre Charlotte; Schieber L. Nicole; Falconet Denis; Wangpraseurt Daniel; Schertel Lukas; Stryhanyuk Hryhoriy; ...
    Publisher: HAL CCSD
    Project: EC | CORBEL (654248), EC | ChloroMito (833184)

    Endosymbioses have shaped the evolutionary trajectory of life and remain ecologically important. Investigating oceanic photosymbioses can illuminate how algal endosymbionts are energetically exploited by their heterotrophic hosts and inform on putative initial steps of ...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Agathe Marcelot; Ambre Petitalot; Virginie Ropars; Marie-Hélène Le Du; Camille Samson; Stevens Dubois; Guillaume Hoffmann; Simona Miron; Philippe Cuniasse; Jose Antonio Marquez; ...
    Publisher: HAL CCSD
    Project: EC | iNEXT-Discovery (871037), EC | iNEXT (653706)

    Barrier-to-autointegration factor (BAF), encoded by the BANF1 gene, is an abundant and ubiquitously expressed metazoan protein that has multiple functions during the cell cycle. Through its ability to cross-bridge two double-stranded DNA (dsDNA), it favours chromosome c...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Jan Felix; Claire Siebert; Julia Novion Ducassou; Jérôme Nigou; Pierre Garcia; Angélique Fraudeau; Karine Huard; Caroline Mas; Céline Brochier-Armanet; Yohann Couté; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | RespViRALI (789385)

    AbstractFrancisella tularensis is one of the most virulent pathogenic bacteria causing the acute human respiratory disease tularemia. While the mechanisms underlying F. tularensis pathogenesis are largely unknown, previous studies have shown that a F. novicida transposo...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Matthew Jessop; Clarissa Liesche; Jan Felix; Ambroise Desfosses; Megghane Baulard; Virgile Adam; Angélique Fraudeau; Karine Huard; Gregory Effantin; Jean-Philippe Kleman; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | Chap4Resp (647784), EC | RespViRALI (789385)

    Pathogenic and commensal bacteria often have to resist the harsh acidity of the host stomach. The inducible lysine decarboxylase LdcI buffers the cytosol and the local extracellular environment to ensure enterobacterial survival at low pH. Here, we investigate the acid ...

    Add to ORCIDorcid
  • publication . Preprint . 2021
    Open Access English
    Authors:
    Eleftherios Zarkadas; Hong Zhang; Wensheng Cai; Gregory Effantin; Jonathan Perot; Jacques Neyton; Christophe Chipot; Guy Schoehn; François Dehez; Hugues Nury;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PentaBrain (637733), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Inaccurately perceived as niche drugs, antiemetics are key elements of cancer treatment alleviating the most dreaded side effect of chemotherapy. Serotonin 5-HT3 receptor antagonists are the most commonly prescribed class of drugs to control chemotherapy-induced nausea ...

    Add to ORCIDorcid
  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Christophe Caillat; Guilligay D; Torralba J; Nikolas Friedrich; Nieva Jl; Alexandra Trkola; Chris Chipot; François Dehez; Winfried Weissenhorn;
    Publisher: eLife Sciences
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | EAVI2020 (681137)

    The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antib...

    Add to ORCIDorcid
  • publication . Part of book or chapter of book . 2020
    Open Access English
    Authors:
    Alexandre Frechard; Grigory Sharov; Maximilien Werderer; Patrick Schultz;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | INRT (ANR-10-LABX-0030)

    International audience; Electron microscopy is a powerful tool for studying the homogeneity and structure of biomolecular complexes. The small wavelength of electron and the availability of electron optics enable the direct visualization of macromolecular assemblies in ...

    Add to ORCIDorcid
388 research outcomes, page 1 of 39