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727 research outcomes, page 1 of 73
  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Valéry Ridde; Lara Gautier; Christian Dagenais; Fanny Chabrol; Renyou Hou; Emmanuel Bonnet; Pierre-Marie David; Patrick Cloos; Arnaud Duhoux; Jean-Christophe Lucet; ...
    Publisher: BioMed Central

    Abstract Background All prevention efforts currently being implemented for COVID-19 are aimed at reducing the burden on strained health systems and human resources. There has been little research conducted to understand how SARS-CoV-2 has affected health care systems an...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini; Pierre-Yves Boëlle; Vittoria Colizza;
    Publisher: Nature Publishing Group UK
    Project: ANR | DataRedux (ANR-19-CE46-0008), EC | MOOD (874850), ANR | SPHINx (ANR-17-CE36-0008)

    As countries in Europe implement strategies to control the COVID-19 pandemic, different options are chosen regarding schools. Through a stochastic age-structured transmission model calibrated to the observed epidemic in Île-de-France in the first wave, we explored scena...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Mariana Galvão Ferrarini; Avantika Lal; Rita Rebollo; Andreas J. Gruber; Andrea Guarracino; Itziar Martinez Gonzalez; Taylor Floyd; Daniel Siqueira de Oliveira; Justin Shanklin; Ethan Beausoleil; ...
    Publisher: HAL CCSD

    Ferrarini & Lal et al. developed a novel bioinformatic pipeline to explore how SARS-CoV-2 interacts with human respiratory cells using public available host gene expression and viral genome sequence data. Several human genes and proteins were predicted to play a role in...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Héléna Mosbah; Muriel Coupaye; Flavien Jacques; Maithe Tauber; Karine Clément; Jean-Michel Oppert; Christine Poitou;
    Publisher: HAL CCSD

    Abstract Background Prader-Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction leading to obesity and behavioral disabilities, including eating disorders (EDs). We evaluated the effects of the COVID-19 infection and lockdown on mental and...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Stüder, François; Petit, Jean-Louis; Engelen, Stefan; Mendoza-Parra, Marco Antonio;
    Publisher: HAL CCSD

    AbstractSince December 2019, the emergence of a novel coronavirus responsible for a severe acute respiratory syndrome (SARS-CoV-2) is accountable for a major pandemic situation. As consequence, a major effort worldwide has been performed for the development of viral dia...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Maria Castaldo; Tommaso Venturini; Paolo Frasca; Floriana Gargiulo;
    Publisher: Springer Science and Business Media LLC

    Comment: Under review

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  • publication . Preprint . 2021
    English
    Authors:
    Malgorzata Wygrecka; Anna Birnhuber; Benjamin Seeliger; Laura Michalick; Oleg Pak; Astrid-Solveig Schultz; Fabian Schramm; Martin Zacharias; Gregor Gorkiewicz; Sascha David; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    AbstractThe high incidence of thrombotic events suggests a possible role of the contact system pathway in COVID-19 pathology. Here, we demonstrate altered levels of factor XII (FXII) and its activation products in two independent cohorts of critically ill COVID-19 patie...

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  • publication . Preprint . 2021
    Open Access English
    Authors:
    Marion Ferren; Valérie Favede; Didier Decimo; Mathieu Iampietro; Nicole A P Lieberman; Jean-Luc Weickert; Rodolphe Pelissier; Magalie Mazelier; Olivier Terrier; Anne Moscona; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    Abstract SARS-CoV-2 has caused a global pandemic of Covid-19 since its emergence in December 2019. The infection causes a severe acute respiratory syndrome and may also lead to central nervous system infection and neurological sequelae. We developed and characterized tw...

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  • publication . Preprint . 2021
    Open Access English
    Authors:
    Marie-Laure Fogeron; Roland Montserret; Zehnder J; Nguyen M; Marie Dujardin; Brigandat L; Cole L; Ninot-Pedrosa M; Lauriane Lecoq; Beat H. Meier; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    AbstractORF7b is an accessory protein of SARS-CoV-2, the virus behind the COVID-19 pandemic. Using cell-free synthesized ORF7b, we experimentally show that ORF7b assembles into stable multimers. The ORF7b sequence shows a transmembrane segment, which multimerizes throug...

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  • publication . Preprint . 2021
    Open Access English
    Authors:
    Benjamin Charvet; Magalie Mazelier; Joanna Brunel; Justine Pierquin; Said Mougari; Matthieu Iampietro; Didier Decimo; Nelly Queruel; Cyrille Matthieu; Branka Horvat; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    Abstract Patients with COVID-19 may develop abnormal inflammatory response and lymphopenia, followed in some cases by delayed-onset syndromes, often long-lasting after resolution of the initial SARS-CoV-2 infection. As viral infections may activate human endogenous retr...

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727 research outcomes, page 1 of 73