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123 Research products, page 1 of 13

  • Publications
  • Open Access
  • Article
  • Conference object
  • English
  • INRIA a CCSD electronic archive server
  • COVID-19

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  • Open Access English
    Authors: 
    Tamas Fulop; Anis Larbi; Graham Pawelec; Alan A. Cohen; Guillaume Provost; Abedelouahed Khalil; Guy Lacombe; Serafim Rodrigues; Mathieu Desroches; Katsuiku Hirokawa; +2 more
    Publisher: HAL CCSD
    Country: France

    International audience; Organismal ageing is associated with many physiological changes, including differences in the immune system of most animals. These differences are often considered to be a key cause of age-associated diseases as well as decreased vaccine response...

  • Open Access English
    Authors: 
    Ivan Lerner; Arnaud Serret-Larmande; Bastien Rance; Nicolas Garcelon; Anita Burgun; Laurent Chouchana; Antoine Neuraz;
    Publisher: HAL CCSD
    Country: France

    Background Patients hospitalized for a given condition may be receiving other treatments for other contemporary conditions or comorbidities. The use of such observational clinical data for pharmacological hypothesis generation is appealing in the context of an emerging...

  • Open Access English
    Authors: 
    Qi Luo; Ryan Weightman; Sean T. McQuade; Mateo Díaz; Emmanuel Trélat; William Barbour; Dan Work; Samitha Samaranayake; Benedetto Piccoli;
    Country: France

    <p style='text-indent:20px;'>During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioni...

  • Open Access English
    Authors: 
    Muriel Rabilloud; Benjamin Riche; Jean François Etard; Mad-Hélénie Elsensohn; Nicolas Voirin; Thomas Bénet; Jean Iwaz; René Ecochard; Philippe Vanhems;
    Publisher: HAL CCSD
    Country: France

    Background Worldwide, COVID-19 outbreaks in nursing homes have often been sudden and massive. The study investigated the role SARS-CoV-2 virus spread in nearby population plays in introducing the disease in nursing homes. Material and methods This was carried out thr...

  • Open Access English
    Authors: 
    Lersy, François; Bund, Caroline; Anheim, Mathieu; Mondino, Marie; Noblet, Vincent; Lazzara, Shirley; Phillipps, Clélie; Collange, Olivier; Oulehri, Walid; Mertes, Paul-Michel; +12 more
    Publisher: HAL CCSD
    Country: France

    Background and Objectives: Cerebral complications related to the COVID-19 were documented by brain MRIs during the acute phase. The purpose of the present study was to describe the evolution of these neuroimaging findings (MRI and FDG-PET/CT) and describe the neurocogni...

  • Open Access English
    Authors: 
    Marina Sánchez-Rico; Frédéric Limosin; Raphaël Vernet; Nathanaël Beeker; Antoine Neuraz; Carlos Blanco; Mark Olfson; Cédric Lemogne; Pierre Meneton; Christel Daniel; +10 more
    Publisher: HAL CCSD
    Country: France

    International audience; Background: Based on its antiviral activity, anti-inflammatory properties, and functional inhibition effects on the acid sphingomyelinase/ceramide system (FIASMA), we sought to examine the potential usefulness of the H1 antihistamine hydroxyzine ...

  • Open Access English
    Authors: 
    Marine Gauthier; Denis Agniel; Rodolphe Thiébaut; Boris P. Hejblum;
    Publisher: HAL CCSD
    Country: France

    SummaryState-of-the-art methods for single-cell RNA sequencing (scRNA-seq) Differential Expression Analysis (DEA) often rely on strong distributional assumptions that are difficult to verify in practice. Furthermore, while the increasing complexity of clinical and biolo...

  • Publication . Conference object . Preprint . 2021
    Open Access English
    Authors: 
    Muhammad Umar B Niazi; Alain Kibangou; Carlos Canudas de Wit; Denis Nikitin; Liudmila Tumash; Pierre-Alexandre Bliman;
    Publisher: HAL CCSD
    Country: France
    Project: EC | Scale-FreeBack (694209)

    Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment or vaccine is available. In thi...

  • Publication . Conference object . Article . 2021
    Open Access English
    Authors: 
    Kibangou, Alain; Moyo, Thembani; Musakwa, Walter;
    Publisher: HAL CCSD
    Country: France

    International audience; Congestion is a phenomenon that impacts most cities in the world. Due to car emissions, it is a significant source of pollution. Even though mobility restrictions can reduce congestion and emissions, essential activities still need cars. With loc...

  • Open Access English
    Authors: 
    Wallin, Rosanne; Van Iersel, Leo; Kelk, Steven; Stougie, Leen;
    Countries: France, France, Netherlands

    Abstract Background Rooted phylogenetic networks are used to display complex evolutionary history involving so-called reticulation events, such as genetic recombination. Various methods have been developed to construct such networks, using for example a multiple sequenc...