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10,035 research outcomes, page 1 of 1,004
  • publication . Article . 2021
    Open Access English
    Authors:
    Benjamin Bonnard; Ernesto Martínez-Martínez; Amaya Fernández-Celis; Marie Pieronne-Deperrois; Quoc-Tuan Do; Isbaal Ramos; Patrick Rossignol; Faiez Zannad; Paul Mulder; Antoine Ouvrard-Pascaud; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | FIGHT-HF (ANR-15-RHUS-0004), EC | FIBRO-TARGETS (602904), ANR | RENOMIR (ANR-16-CE14-0021)

    International audience; Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological consequences of cardiovascular and renal damage. We aimed to design chemical NGAL inhibito...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Mariana L. Ferrari; Spyridoula N. Charova; Philippe J. Sansonetti; Efstratios Mylonas; Anastasia D. Gazi;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | EIMID-IAPP (217768), EC | DECRYPT (339579), EC | HOMEOEPITH (232798)

    <jats:p>Bacterial Type III Secretion Systems (T3SSs) are specialized multicomponent nanomachines that mediate the transport of proteins either to extracellular locations or deliver Type III Secretion effectors directly into eukaryotic host cell cytoplasm. <jats:italic>S...

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  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Ozlem Yilmaz; Amélie Patinote; Emmanuelle Com; Charles Pineau; Julien Bobe;
    Publisher: BioMed Central
    Project: EC | FISHEGG (626272)

    <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>We previously reported the results of CRISPR/Cas9 knock-out (KO) of type-I and type-III vitellogenins (Vtgs) in zebrafish, which provided the first experimental evidence on essential...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Marie-Odile Bristeau; Bernard Di Martino; Anne Mangeney; Jacques Sainte-Marie; Fabien Souillé;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | SLIDEQUAKE (617472)

    We present several time dependent analytical solutions for the incompressible Euler system with free surface. These analytical solutions give quantitative descriptions of some physical phenomena and can be used as reference solutions when validating numerical simulation...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Burgos, Ninon; Cardoso, M. Jorge; Samper-González, Jorge; Habert, Marie-Odile; Durrleman​, Stanley; Ourselin, Sébastien; Colliot, Olivier;
    Publisher: HAL CCSD
    Project: EC | PRESTIGE (609102), ANR | PRAIRIE (ANR-19-P3IA-0001), CIHR , EC | LEASP (678304), NIH | The Frontotemporal Lobar ... (5R01AG032306-02), NIH | Alzheimers Disease Neuroi... (1U01AG024904-01)

    International audience; Purpose:In clinical practice, positron emission tomography (PET) images are mostly analysed visually, but the sensitivity and specificity of this approach greatly depends on the observer's experience. Quantitative analysis of PET images would all...

  • publication . Article . Conference object . 2021
    Open Access English
    Authors:
    Guillaume Grzych; Oscar Chávez-Talavera; Amandine Descat; Dorothée Thuillier; An Verrijken; Mostafa Kouach; Vanessa Legry; Helene Verkindt; Violeta Raverdy; Benjamin Legendre; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | ImmunoBile (694717), EC | RESOLVE (305707)

    Graphical abstract

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  • publication . Preprint . 2021
    Open Access English
    Authors:
    Nabiev, Igor; Sukhanova, Alyona; Even-Desrumeaux, Klervi; Chames, Patrick; Baty, Daniel; Artemyev, Mikhail; OLEINIKOV, Vladimir;
    Publisher: HAL CCSD
    Project: EC | NAMDIATREAM (246479)

    International audience; Nanoparticle-based biodetection commonly employs monoclonal antibodies (mAbs) for targeting. Although several types of conjugates have been used for biomarker labeling, the large size of mAbs limits the number of ligands per nanoparticle, impedes...

  • publication . Preprint . 2021
    Open Access English
    Authors:
    Routier, Alexandre; Burgos, Ninon; Díaz, Mauricio; Bacci, Michael; Bottani, Simona; El-Rifai, Omar; Fontanella, Sabrina; Gori, Pietro; Guillon, Jérémy; Guyot, Alexis; ...
    Publisher: HAL CCSD
    Project: EC | HBP SGA1 (720270), EC | LEASP (678304), EC | PRESTIGE (609102), EC | EuroPOND (666992), ANR | PRAIRIE (ANR-19-P3IA-0001)

    We present Clinica (www.clinica.run), an open-source software platform designed to make clinical neuroscience studies easier and more reproducible. Clinica aims for researchers to i) spend less time on data management and processing, ii) perform reproducible evaluations...

  • publication . Article . 2021
    Open Access English
    Authors:
    Jakobczyk, Hélène; Debaize, Lydie; Soubise, Benoit; Avner, Stéphane; Rouger-Gaudichon, Jérémie; Commet, Séverine; Jiang, Yan; Sérandour, Aurélien A.; Rio, Anne-Gaëlle; Carroll, Jason S.; ...
    Publisher: BioMed Central
    Project: EC | ALLRUN (291851)

    Funder: FP7 People: Marie-Curie Actions; doi: http://dx.doi.org/10.13039/100011264; Grant(s): 291851

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  • publication . Article . 2021
    Open Access English
    Authors:
    Jean-Paul Motta; Corinne Rolland; Anissa Edir; Ana-Carolina Florence; David Sagnat; Chrystelle Bonnart; Perrine Rousset; Laura Guiraud; Muriel Quaranta-Nicaise; Emmanuel Mas; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | ELAPROB-IBD (ANR-12-BSV1-0030), EC | EPIMACASE (627487), EC | PIPE (310973)

    <jats:title>Abstract</jats:title><jats:p>Imbalance between proteases and their inhibitors plays a crucial role in the development of Inflammatory Bowel Diseases (IBD). Increased elastolytic activity is observed in the colon of patients suffering from IBD. Here, we aimed...

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10,035 research outcomes, page 1 of 1,004