Quick search
Advanced search in
Field to searchTerm
Add rule
Filters (2)
Download Results
58 research outcomes, page 1 of 6
  • publication . Article . 2020
    Open Access English
    Authors:
    Frank Møller Aarestrup; A. Albeyatti; W. J. Armitage; Charles Auffray; L. Augello; Rudi Balling; N. Benhabiles; G. Bertolini; Jan G. Bjaalie; Michaela Black; ...
    Project: EC | B-CAST (633784), EC | SYSCOL (258236), EC | INSTRUCT-ULTRA (731005), EC | CONNECARE (689802), EC | SYSCID (733100), EC | EMIF (115372), EC | ERA PerMed (779282), EC | E-COMPARED (603098), EC | SYSCLAD (305457), EC | EuroPOND (666992),...

    The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European Health Research and Innovation C...

    Add to ORCIDorcid
  • publication . Preprint . 2020
    Open Access English
    Authors:
    Trindade, Inês; Invernici, Michele; Cantini, Francesca; Louro, Ricardo O; Piccioli, Mario;
    Project: EC | TIMB3 (810856)

    The current paradigm for protein structure determination by NMR spectroscopy has thus far been based on collecting distance restrains between pairs of nuclei in the form of nuclear Overhauser enhancements (NOE). These, have in some circumstances been supplemented with o...

  • publication . Article . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Lidia Ruiz; Zuzanna Kaczmarska; Tiago Gomes; Eric Aragón; Carles Torner; Regina Freier; Blazej Baginski; Pau Martin-Malpartida; Natàlia de Martin Garrido; José A. Márquez; ...
    Publisher: Elsevier BV
    Project: EC | PREBIST (754558), EC | iNEXT (653706), EC | PROBIST (754510)

    Highlights • MH1 domains of BMP-activated Smads populate a dimer-monomer equilibrium. • Swapping loop1 between BMP- and TGFβ Smads turns dimers into monomers and vice versa. • BMP-responsive genomic regions have a lower average count of motifs than TGFβ ones.

    Add to ORCIDorcid
  • publication . Article . Preprint . Other literature type . 2019
    Open Access English
    Authors:
    Yannick Blum; Jan Mikelson; Maciej Dobrzyński; Hyunryul Ryu; Marc-Antoine Jacques; Noo Li Jeon; Mustafa Khammash; Olivier Pertz;
    Publisher: Nature Publishing Group
    Project: EC | TRANSVAC2 (730964), SNSF | Understanding single cell... (IZKSZ3_162195)

    Abstract Stimulation of PC‐12 cells with epidermal (EGF) versus nerve (NGF) growth factors (GFs) biases the distribution between transient and sustained single‐cell ERK activity states, and between proliferation and differentiation fates within a cell population. We rep...

    Add to ORCIDorcid
  • publication . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Benjamin G Butt; Danielle J Owen; Cy M. Jeffries; Lyudmila Ivanova; Jack W. Houghton; Firoz Ahmed; Robin Antrobus; Dmitri I. Svergun; John J. Welch; Colin M. Crump; ...
    Persistent Identifiers
    Publisher: bioRxiv
    Project: WT | Molecular mechanisms of m... (098406), EC | iNEXT (653706), EC | BIOSTRUCT-X (283570)

    AbstractHerpesviruses are an ancient family of highly-prevalent human and animal pathogens that acquire their membrane envelopes in the cytoplasm of infected cells. While multiple conserved viral proteins are known to be required for efficient herpesvirus production, ma...

    Add to ORCIDorcid
  • publication . Article . Preprint . Other literature type . 2019
    Open Access
    Authors:
    Iain M Hay; Gareth W. Fearnley; Pablo Rios; Maja Köhn; Hayley J. Sharpe; Janet E. Deane;
    Publisher: Springer Science and Business Media LLC
    Project: WT , EC | BIOSTRUCT-X (283570)

    Receptor-linked protein tyrosine phosphatases (RPTPs) usually contain an active membrane proximal domain and an inactive pseudophosphatase domain. Here, the authors characterize an RPTP with two pseudophosphatase domains, providing evidence that it may act as a decoy re...

    Add to ORCIDorcid
  • publication . Preprint . Other literature type . Conference object . Part of book or chapter of book . 2019
    Open Access English
    Authors:
    Miriam Baglioni; Alessia Bardi; Argiro Kokogiannaki; Paolo Manghi; Katerina Iatropoulou; Pedro Príncipe; André Vieira; Lars Holm Nielsen; Harry Dimitropoulos; Ioannis Foufoulas; ...
    Project: EC | OpenAIRE-Advance (777541), EC | OpenAIRE-Connect (731011), WT

    First Online 30 August 2019

    Add to ORCIDorcid
  • publication . Article . Other literature type . Preprint . 2019
    Open Access English
    Authors:
    Jan Felix; Katharina Weinhäupl; Christophe Chipot; François Dehez; Audrey Hessel; Diego F. Gauto; Cecile Morlot; Olga Abian; Irina Gutsche; Adrián Velázquez-Campoy; ...
    Project: EC | PROTDYN2FUNCTION (311318)

    18 pags., 6 figs., 1 tab. -- Open Access funded by Creative Commons Atribution Licence 4.0

    Add to ORCIDorcid
  • publication . Article . Other literature type . Preprint . 2019
    Open Access English
    Authors:
    Tiago N. Cordeiro; Nathalie Sibille; Pierre Germain; Philippe Barthe; Abdel Boulahtouf; Frédéric Allemand; Rémy Bailly; Valérie Vivat; Christine Ebel; Alessandro Barducci; ...
    Persistent Identifiers
    Publisher: HAL CCSD

    AbstractThe retinoic acid receptors (RARs) form heterodimers with retinoid X receptors (RXRs) and control gene transcription in response to ligand binding and via allosteric activation of the C-termini helix (helix H12) of its ligand-binding domain. Herein we show that ...

    Add to ORCIDorcid
  • publication . Article . 2019
    Open Access
    Authors:
    Karin H. Müller; Robert Hayward; Rakesh Rajan; Meredith Whitehead; Andrew M. Cobb; Sadia Ahmad; Mengxi Sun; Ieva Goldberga; Rui Li; Uliana Bashtanova; ...
    Publisher: Elsevier BV
    Project: EC | iNEXT (653706), UKRI | Nano-Optics to controlled... (EP/L027151/1), UKRI | Cambridge NanoScience thr... (EP/G037221/1)

    Müller et al. investigate the physicochemical process of extracellular matrix calcification in both physiological (bone) and pathological (vascular calcification) contexts. They find that oxidative stress-induced poly(ADP-ribose) nucleates calcium phosphate mineral crys...

    Add to ORCIDorcid
58 research outcomes, page 1 of 6