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9,134 Research products, page 1 of 914

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  • 2018-2022
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  • COVID-19

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  • Open Access English
    Authors: 
    de Bock, Ellen; Herman, Eline S.; Bastian, Okan W.; Filipe, Mando D.; Vriens, Menno R.; Richir, Milan C.;

    Background: To provide for Coronavirus Disease 2019 (COVID-19) healthcare capacity, (surgical oncology) guidelines were established, forcing to alter the timing of performing surgical procedures. It is essential to determine whether these guidelines have led to disease progression. This study aims to give an insight into the number of surgical oncology procedures performed during the pandemic and provide information on short-term clinical outcomes. Materials and methods: A systematic literature search was performed on all COVID-19 articles including operated patients, published before March 21, 2022. Meta-analysis was performed to visualize the number of performed surgical oncology procedures during the pandemic compared to the pre-pandemic period. Random effects models were used for evaluating short-term clinical outcomes. Results: Twenty-four studies containing 6762 patients who underwent a surgical oncology procedure during the pandemic were included. The number of performed surgical procedures for an oncological pathology decreased (−26.4%) during the pandemic. The number of performed surgical procedures for breast cancer remained stable (+0.3%). Moreover, no difference was identified in the number of ≥T2 (OR 1.00, P = 0.989), ≥T3 (OR 0.95, P = 0.778), ≥N1 (OR 1.01, P = 0.964) and major postoperative complications (OR 1.55, P = 0.134) during the pandemic. Conclusion: The number of performed surgical oncology procedures during the COVID-19 pandemic decreased. In addition, the number of performed surgical breast cancer procedures remained stable. Oncological staging and major postoperative complications showed no significant difference compared to pre-pandemic practice. During future pandemics, the performed surgical oncology practice during the first wave of the COVID-19 pandemic seems appropriate for short-term results.

  • Other research product . Other ORP type . 2022
    Open Access
    Authors: 
    Taylor, Steven;
    Publisher: Zenodo

    According to the World Health Organization, pandemic fatigue poses a serious threat for managing COVID-19. Pandemic fatigue is characterized by progressive decline in adherence to social distancing (SDIS) guidelines, and is thought to be associated with pandemic-related emotional burnout. Little is known about the nature of pandemic fatigue; for example, it is unclear who is most likely to develop pandemic fatigue. We sought to evaluate this issue based on data from 5,812 American and Canadian adults recruited during the second year of the COVID-19 pandemic. Past-year decline in adherence to SDIS had a categorical latent structure according to Latent Class Analysis, consisting of a group adherent to SDIS (Class 1: 92% of the sample) and a group reporting a progressive decline in adherence to SDIS (i.e., pandemic fatigue; Class 2: 8% of the sample). Class 2, compared to Class 1, was associated with greater pandemic-related burnout, pessimism, and apathy about the COVID-19 pandemic. They also tended to be younger, perceived themselves to be more affluent, tended to have greater levels of narcissism, entitlement, and gregariousness, and were more likely to report having been previously infected with SARSCOV2, which they regarded as an exaggerated threat. People in Class 2 also self-reported higher levels of pandemic-related stress, anxiety, and depression, and described making active efforts at coping with SDIS restrictions, which they perceived as unnecessary and stressful. People in Class 1 generally reported that they engaged in SDIS for the benefit of themselves and their community, although 35% of this class also feared they would be publicly shamed if they did not comply with SDIS guidelines. The findings suggest that pandemic fatigue affects a substantial minority of people and even many SDIS-adherent people experience emotionally adverse effects (i.e., fear of being shamed). Implications for the future of SDIS are discussed.

  • Open Access Spanish
    Authors: 
    Encarnación González Flores; Rubén Alba Ruiz; María Del Carmen Olvera Porcel; Juan Pérez Ortega; Mª del Mar Rodríguez del Águila;
    Publisher: Zenodo

    El HUVN se encuentra dotado de una Cartera de Servicios de alta complejidad, lo que constituye una fortaleza para la investigación de primer nivel, unido a un considerable número de profesionales y grupos investigadores orientados a la investigación e innovación traslacional, epidemiológica y clínica. Los resultados en Investigación en los últimos años (2018-2021) observamos que la evolución ha sido positiva en muchos aspectos, incremento en el número de publicaciones y alto porcentaje de las mismas en revistas Q1. En 2021 el aumento del sumatorio del Factor de impacto del HUVN con respecto 2020 y años anteriores es considerable; el impacto que ha tenido la pandemia de la COVID-19 en las publicaciones científicas, ha aumentado notablemente las citas de las revistas de medicina, cuidados intensivos, salud pública, enfermedades infecciosas, inmunología, etc... con el correspondiente aumento del valor de este indicador a la hora de calcularlo.

  • Open Access
    Authors: 
    Arief, Neneng Nurlaela; Putra Pratama, Andika; Budiman, Dicky; Barata, Vinka Amalia Hasta; Tirdasari, Nyanyu Lathifah;
    Publisher: Zenodo

    Background: Concerns over an infodemic following a surge in health misinformation circulating on social media sets out the government's priority for Indonesia. Given the urgent work on the coronavirus disease 2019 (COVID-19) response, the government collaborated with health-related spokespersons and influencers with a medical background by starting a COVID-19 public education campaign on social media. A collaborative initiative involved health spokespersons from government and non-government to clarify misinformation about COVID-19. Methods: The primary purpose of this research is to compare government and non-government spokespersons by examining their role in educating about the COVID-19 vaccine and health services. This study employed comparative factor analysis and non-participatory observation toward the media activity of spokespersons in Indonesia. Using a questionnaire, this study examines the dimensions of public campaigns, risk communication, health and emergency, leadership, and communication from Indonesian spokespersons. The data collection was conducted in two stages. The first stage was a pilot study that collected data from 102 respondents, the second stage collected data from 276 respondents. Results: Findings show that utilizing the spokesperson is important due to its capabilities of reaching diverse audiences, and improving public engagement, trustworthiness, and credibility. Conclusions: With the combination of health authorities spokespersons and health influencers in Indonesia, this study provides valuable insights for communication management in developing and supporting the role of health authorities from the government, non-government as well as medical sectors.

  • Open Access
    Authors: 
    Roseline Oluwaseun Ogundokun; Abdulwasiu Bolakale Adelodun; Akeem Olatunji Yekini; Akinyemi Omololu Akinrotimi;
    Publisher: Zenodo

    The document is on supplementary materials on the results obtained on analyzing and investigating the impact of the COVID-19 pandemic and the policies made by the government on human rights.

  • Open Access English
    Authors: 
    Johansson, Veronica; Wänström, Linda; Ramme, Kim; Nilsdotter Swartswe, Johanna; Kallio, Sakari;
    Publisher: Zenodo

    Template for the national survey questionnaire on demographics, background factors, symptoms and changes over time, health impacts, and information needs and practices among the group of long-COVID / post-COVID sufferers in Sweden conducted within the research project CiLC-S - Crowdsourcing Long-COVID Sweden in 2021. The survey is designed for anonymous participation, and open digital methods distribution through social media and web channels.

  • Other research product . Other ORP type . 2022
    Open Access English
    Authors: 
    Manz, Xue D.; Bogaard, Harm Jan; Aman, Jurjan;

    Increasing evidence indicates that inflammation promotes thrombosis via a VWF (von Willebrand factor)-mediated mechanism. VWF plays an essential role in maintaining the balance between blood coagulation and bleeding, and inflammation can lead to aberrant regulation. VWF is regulated on a transcriptional and (post-)translational level, and its secretion into the circulation captures platelets upon endothelial activation. The significant progress that has been made in understanding transcriptional and translational regulation of VWF is described in this review. First, we describe how VWF is regulated at the transcriptional and post-translational level with a specific focus on the influence of inflammatory and immune responses. Next, we describe how changes in regulation are linked with various cardiovascular diseases. Recent insights from clinical diseases provide evidence for direct molecular links between inflammation and thrombosis, including atherosclerosis, chronic thromboembolic pulmonary hypertension, and COVID-19. Finally, we will briefly describe clinical implications for antithrombotic treatment.

  • Open Access English
    Authors: 
    de Carvalho, Victor Diogho Heuer; Nepomuceno, Thyago Celso Cavalcante; Poleto, Thiago; Costa, Ana Paula Cabral Seixas;
    Publisher: Zenodo

    Set of supplementary tables and figures obtained for the analysis of topics in space and time about the Brazilian Immunization Program against COVID-19. These elements are: Table S1: Parameters used in the scraping script; Table S2: Example of the georeferenced corpus, containing the first five rows; Table S3: The 23 topics extracted using LDA algorithm; Table S4: Tweets amounts according to each topic; Figure S1: Topic 1 distribution on the Brazilian territory; Figure S2: Topic 2 distribution on the Brazilian territory; Figure S3: Topic 4 distribution on the Brazilian territory; Figure S4: Topic 5 distribution on the Brazilian territory; Figure S5: Topic 6 distribution on the Brazilian territory; Figure S6: Topic 7 distribution on the Brazilian territory; Figure S7: Topic 8 distribution on the Brazilian territory; Figure S9: Topic 10 distribution on the Brazilian territory; Figure S10: Topic 11 distribution on the Brazilian territory; Figure S11: Topic 12 distribution on the Brazilian territory; Figure S12: Topic 14 distribution on the Brazilian territory; Figure S13: Topic 15 distribution on the Brazilian territory; Figure S14: Topic 16 distribution on the Brazilian territory; Figure S15: Topic 17 distribution on the Brazilian territory; Figure S16: Topic 18 distribution on the Brazilian territory; Figure S17: Topic 19 distribution on the Brazilian territory; Figure S18: Topic 20 distribution on the Brazilian territory; Figure S19: Topic 21 distribution on the Brazilian territory; Figure S20: Topic 22 distribution on the Brazilian territory; Figure S21: Topic 23 distribution on the Brazilian territory.

  • English
    Authors: 
    Sigit, Hermawan;
    Publisher: Universitas Muhammadiyah Sidoarjo
    Country: Indonesia
  • Other research product . Other ORP type . 2022
    Open Access
    Authors: 
    Interdisciplinary Physics Team (InPhyT); actions-user; Maria; Pietro Monticone;
    Publisher: Zenodo

    Data updated as of 2022-10-26

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