Advanced search in
Research products
arrow_drop_down
Searching FieldsTerms
Any field
arrow_drop_down
includes
arrow_drop_down
Include:
10,562 Research products, page 1 of 1,057

  • Other research products
  • English
  • COVID-19

10
arrow_drop_down
Date (most recent)
arrow_drop_down
  • Embargo English
    Authors: 
    Meza Miranda, Eliana Romina; Parra Soto, Solange Liliana; Durán Agüero, Samuel; Gómez, Georgina; Carpio Arias, Valeria; Ríos Castillo, Israel; Murillo, Ana Gabriela; Araneda, Jacqueline; Morales, Gladys; Cavagnari, Brian M.; +6 more
    Country: Argentina

    Abstract: Introduction: Short sleep, physical inactivity, and being locked up are risk factors for weight gain. Objective: We evaluated weight gain according to sex, age, hours of sleep and physical activity in university students from 10 Latin American countries during the COVID-19 pandemic. Methods: Cross-sectional and multicenter study (n = 4880). Results: The average age was 22.5 ± 4.4 years. 60.2% were currently locked up. 73.6% were women, 48.2% increased their body weight, 66% reported insufficient sleep hours, and 65.9% were inactive. Women gained more weight than men (73.2%) and younger students gained more weight (85.1%). Those who had insufficient sleep hours gained most weight (67.6%). Inactive participants gained most weight (74.7%). Students who have insufficient sleep are 21% more likely to have changes in body weight compared to students who have optimal sleep. Conclusion: The increase in body weight and its risk factors during confinement should be considered as emerging from public health.

  • Embargo English
    Authors: 
    Barrantes, Francisco José;
    Country: Argentina

    Abstract: Critical to viral infection are the multiple interactions between viral proteins and host-cell counterparts. The first such interaction is the recognition of viral envelope proteins by surface receptors that normally fulfil other physiological roles, a hijacking mechanism perfected over the course of evolution. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), has successfully adopted this strategy using its spike glycoprotein to dock on the membraneboundmetalloprotease angiotensin-converting enzyme 2 (ACE2). The crystal structures of several SARS-CoV-2 proteins alone or in complex with their receptors or other ligands were recently solved at an unprecedented pace. This accomplishment is partly due to the increasing availability of data on other coronaviruses and ACE2 over the past 18 years. Likewise, other key intervening actors and mechanisms of viral infection were elucidated with the aid of biophysical approaches. An understanding of the various structurally important motifs of the interacting partners provides key mechanistic information for the development of structure-based designer drugs able to inhibit various steps of the infective cycle, including neutralizing antibodies, small organic drugs, and vaccines. This review analyzes current progress and the outlook for future structural studies.

  • Embargo English
    Authors: 
    Otero Losada, Matilde; Petrovsky, Nikolai; Alami, Abdallah; Crispo, James A.; Mattison, Donald; Capani, Francisco; Goetz, Christopher; Krewski, Daniel; Pérez Lloret, Santiago;
    Country: Argentina

    Abstract: Background: Information on neurological and psychiatric adverse events following immunization (AEFIs) with COVID-19 vaccines is limited. Research design & methods: We examined and compared neurological and psychiatric AEFIS reports related to BNT162b2 (Pfizer-BioNTech) and ChAdOx1 (Oxford-AstraZeneca) COVID-19 vaccines and recorded in the United Kingdom Medicines and Healthcare products Regulatory Agency between 9 December 2020 and 30 June 2021. Results: As of 30 June 2021, 46.1 million doses of ChAdOx1 and 30.3 million doses of BNT162b2 had been administered. The most frequently reported AEFI was headache with 1,686 and 575 cases per million doses of ChAdOx1 and BNT162b2, respectively. AEFIs more frequently reported after CHAdOx1 compared with BNT162b2 vaccination were Guillain-Barré syndrome (OR, 95% CI = 2.53, 1.82–3.51), freezing (6.66, 3.12–14.22), cluster headache (1.53, 1.28–1.84), migraine (1.23,1.17–1.30), postural dizziness (1.24,1.13–1.37), tremor (2.86, 2.68–3.05), headache (1.40, 1.38–1.43), paresthesia (1.11, 1.06–1.16), delirium (1.85, 1.45–2.36), hallucination (2.20, 1.82–2.66), poor quality sleep (1.53, 1.26–1.85), and nervousness (1.54, 1.26–1.89) Reactions less frequently reported with ChAdOx1 than with BNT162b2 were Bell’s palsy (0.47, 0.41–0.55), anosmia (0.58, 0.47–0.71), facial paralysis (0.35, 0.29– 0.41), dysgeusia (0.68, 0.62–0.73), presyncope (0.48, 0.42–0.55), syncope (0.63, 0.58–0.67), and anxiety (0.75 (0.67–0.85). Conclusion: Neurological and psychiatric AEFIs were relatively infrequent, but each vaccine was associated with a distinctive toxic profile. Plain Language Summary We examined reports on adverse neurological and psychiatric effects following immunization with BNT162b2 (Pfizer-BioNTech) and ChAdOx1 (Oxford-AstraZeneca) for COVID-19 to the United Kingdom Medicines and Healthcare products Regulatory Agency between 9 December 2020 and 30 June 2021. Adverse effects following immunization (AEFIs) were relatively infrequent. Compared to BNT162b2, Guillain-Barré syndrome, freezing phenomenon, cluster headache, migraine, postural dizziness, tremor, headache, paresthesia, delirium, hallucination, poor quality sleep, and nervousness were more frequently reported for ChAdOx1. Reactions less frequently reported for ChAdOx1 than for BNT162b2 were Bell’s palsy, anosmia, facial paralysis, dysgeusia, presyncope, syncope, and anxiety.

  • English
    Authors: 
    Chen, Dongxuan; Lau, Yiu-Chung; Xu, Xiao-Ke; Wang, Lin; Du, Zhanwei; Tsang, Tim K.; Wu, Peng; Lau, Eric H. Y.; Wallinga, Jacco; Cowling, Benjamin J.; +1 more
    Publisher: Nature Publishing Group UK
    Country: United Kingdom
  • Open Access English
    Authors: 
    Asadpour, Faraz;
    Country: Canada

    Persons with intellectual and developmental disabilities (IDD) are found to be at a greater risk for social isolation during COVID-19 pandemic. While existing literature has examined the challenges faced by persons with IDD, there is a dearth of research that addresses the access and usage of digital technologies by persons with IDD as a solution to stay socially connected during the pandemic. This study therefore investigated the access to and use of digital technologies such as the internet in relation to the risk of social isolation experienced by persons with mild intellectual disabilities ID (with or without developmental disabilities) during the COVID-19 Pandemic in Manitoba. Additionally, barriers to the usage of online technology were explored. Data for a sample of 39 adults were collected using an online survey questionnaire, and phone interviews. The key variables in this study are internet use, access to an electronic device, barriers to the internet usage, loneliness, and social isolation. Loneliness was measured using the Revised UCLA (University of California, Los Angeles) Loneliness Scale. To measure social isolation, the MSNA-ID (Maastricht Social Network Analysis – Intellectual Disabilities) tool was used. The study utilized both descriptive and inferential analyses to address the research objectives. We found that the majority of the study participants (89.5%), had access to the internet and possessed some form of electronic devices for online connection. The most commonly used devices were smartphones, desktop computers, and tablets. The majority of the study participants (67.6%) who had access to the internet and an electronic device used the internet for social connection during the COVID-19 pandemic. The majority of the study participants (53.8%) perceived that their internet usage made them feel less isolated. The use of the internet was associated with a feeling of less isolation. The results further revealed the most prevalent barriers to the usage of the internet as reported by the study participants. The cost of internet service/equipment (20.6%), having access to the internet elsewhere (17.6%), difficulty in using the internet (14.7%), and safety concerns (14.7%) were the most commonly barriers reported by the study participants.

  • English
    Authors: 
    Pachankis, Yang;
    Country: Germany

    Introduction: The research was conducted during the COVID-19 (SARS-CoV-2) lockdown measures of People’s Republic of China (PRC) with a history & continuation of nuclear proliferation, current electronic warfare, metallic pollution from military heavy industry, and actinic radiation pollutants from chip production. Apart from the biomedical harm sources, the purposes behind the source productions such as chips have been the sources of psychological tortures in neuro-cognitive warfare. The research adopted a human security paradigm primarily in mainland China with multilateral and global implications. Methodology: The research was conducted with the pressure of human trafficking conducted by the PRC. It counteracts the PRC’s disinformation with empirical research, analysis, and psychotherapeutic approaches. The meta-analysis demonstrates that PRC’s declared pandemic responses in fact have not contributed to the positive duties in protecting the public’s right to health, and on the contrary, its accumulated environmental determinants along with power intentions only worsened the public’s autonomous selfceare and mutual assistance responses in the public health situations. Results: The environmental factors in PRC substantially undermine the referential values of biomedical data in international settings, and if applicable, biomedical products export in the global supply chain. Genetic technologies based on applied research in telomerase must have thorough assessments in their impacts on telomeres consumption. Renormalization from and further research into nuclear proliferation and environmental determinants is the only way to improve public health. The PRC has never fulfilled any duties to the liberal institutions nor the territorial civil society. Military intervention and peacekeeping are necessary for PRC’s judicial independence.

  • Open Access English
    Authors: 
    Scherer, Ronny; Siddiq, Fazilat; Howard, Sarah K.; Tondeur, Jo;

    In the present study, we tested the common assumption that teachers with more experience consider themselves better prepared for online teaching and learning (OTL). Utilizing the data from a survey of 366 higher-education teachers from Portugal at the beginning of the COVID-19 pandemic in 2020, we performed structural equation modeling to quantify the experience-readiness relationship. The survey contained an assessment of teachers' OTL readiness which was measured by their perceptions of the institutional support, online teaching presence, and TPACK self-efficacy. In contrast to the linearity assumption “the more experienced, the better prepared”, we found robust evidence for a curvilinear relationship. Teachers’ readiness for OTL increased first and then decreased with more experience—this applied especially to the self-efficacy dimension of readiness. Further analyses suggested that the experience-readiness relationship does not only exist at the level of aggregated constructs but also at the level of indicators, that is, specific areas of knowledge, teaching, and support. We argue that both novice and experienced teachers in higher education could benefit from experience-appropriate, pedagogical, and content-related support programs for OTL.

  • English
    Authors: 
    Ozili, Peterson K.;
    Country: Germany

    This paper analyse the looming COVID-19 global debt crisis. The high debt incurred during the pandemic period by many countries combined with tightening global financial conditions such as increase in interest rate can trigger a global debt crisis for heavily indebted countries. I suggest some actions to be taken by richer countries, heavily indebted countries and multilateral organisations to mitigate the looming COVID-19 global debt crisis. Richer countries who are creditors to poor countries should consider debt forgiveness, interest repayment holidays, debt-forgreen swap and other debt relief options. Multilateral organisations should allow affected members to draw on their contributory fund, they should support the G20 Debt Service Suspension Initiative, and engage in debt forgiveness advocacy. Heavily indebted countries should restructure their debt, rebalance policy priorities, focus on alternatives to borrowing, manage their level of debt, and find better ways to manage shocks and crises.

  • Open Access English
    Authors: 
    Julesz Máté;
    Country: Hungary
  • Closed Access English
    Authors: 
    Sequeiros, José; Pereira, Maria Teresa Ribeiro; Oliveira, Marisa; Ferreira, Fernanda A.;
    Country: Portugal

    Available studies and reports, as well as real-time experiences, attest to profound, extensive, long-lasting effects on the supply chain caused by the pandemic. It is thus paramount to rethink the supply chain for medication and health care supplies to build a more resilient and adaptable management process. Data obtained from the NHS portal monthly reports from January 2017 to August 2020 – indicates that at the hospital level the impact was felt the most on the scheduling of medical appointments and prescriptions. Two forecasting methods were selected for this study: Simple Linear Regression and Holt-Winters with the trend and additive seasonality. There was a change in the behavior of hospital patients in the first year of COVID-19 pandemics. This change was shown in two main indicators, the number of hospital consultations and medication expenses. This changed behavior resulted in a decrease in demand for scheduled hospital services, 1.9M less than would be expected under normal conditions, and a foreseeable increase of €432M in the consumption of medicines in the last quarter of 2020, €103M more than in the same period. from the previous year.

Advanced search in
Research products
arrow_drop_down
Searching FieldsTerms
Any field
arrow_drop_down
includes
arrow_drop_down
Include:
10,562 Research products, page 1 of 1,057
  • Embargo English
    Authors: 
    Meza Miranda, Eliana Romina; Parra Soto, Solange Liliana; Durán Agüero, Samuel; Gómez, Georgina; Carpio Arias, Valeria; Ríos Castillo, Israel; Murillo, Ana Gabriela; Araneda, Jacqueline; Morales, Gladys; Cavagnari, Brian M.; +6 more
    Country: Argentina

    Abstract: Introduction: Short sleep, physical inactivity, and being locked up are risk factors for weight gain. Objective: We evaluated weight gain according to sex, age, hours of sleep and physical activity in university students from 10 Latin American countries during the COVID-19 pandemic. Methods: Cross-sectional and multicenter study (n = 4880). Results: The average age was 22.5 ± 4.4 years. 60.2% were currently locked up. 73.6% were women, 48.2% increased their body weight, 66% reported insufficient sleep hours, and 65.9% were inactive. Women gained more weight than men (73.2%) and younger students gained more weight (85.1%). Those who had insufficient sleep hours gained most weight (67.6%). Inactive participants gained most weight (74.7%). Students who have insufficient sleep are 21% more likely to have changes in body weight compared to students who have optimal sleep. Conclusion: The increase in body weight and its risk factors during confinement should be considered as emerging from public health.

  • Embargo English
    Authors: 
    Barrantes, Francisco José;
    Country: Argentina

    Abstract: Critical to viral infection are the multiple interactions between viral proteins and host-cell counterparts. The first such interaction is the recognition of viral envelope proteins by surface receptors that normally fulfil other physiological roles, a hijacking mechanism perfected over the course of evolution. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), has successfully adopted this strategy using its spike glycoprotein to dock on the membraneboundmetalloprotease angiotensin-converting enzyme 2 (ACE2). The crystal structures of several SARS-CoV-2 proteins alone or in complex with their receptors or other ligands were recently solved at an unprecedented pace. This accomplishment is partly due to the increasing availability of data on other coronaviruses and ACE2 over the past 18 years. Likewise, other key intervening actors and mechanisms of viral infection were elucidated with the aid of biophysical approaches. An understanding of the various structurally important motifs of the interacting partners provides key mechanistic information for the development of structure-based designer drugs able to inhibit various steps of the infective cycle, including neutralizing antibodies, small organic drugs, and vaccines. This review analyzes current progress and the outlook for future structural studies.

  • Embargo English
    Authors: 
    Otero Losada, Matilde; Petrovsky, Nikolai; Alami, Abdallah; Crispo, James A.; Mattison, Donald; Capani, Francisco; Goetz, Christopher; Krewski, Daniel; Pérez Lloret, Santiago;
    Country: Argentina

    Abstract: Background: Information on neurological and psychiatric adverse events following immunization (AEFIs) with COVID-19 vaccines is limited. Research design & methods: We examined and compared neurological and psychiatric AEFIS reports related to BNT162b2 (Pfizer-BioNTech) and ChAdOx1 (Oxford-AstraZeneca) COVID-19 vaccines and recorded in the United Kingdom Medicines and Healthcare products Regulatory Agency between 9 December 2020 and 30 June 2021. Results: As of 30 June 2021, 46.1 million doses of ChAdOx1 and 30.3 million doses of BNT162b2 had been administered. The most frequently reported AEFI was headache with 1,686 and 575 cases per million doses of ChAdOx1 and BNT162b2, respectively. AEFIs more frequently reported after CHAdOx1 compared with BNT162b2 vaccination were Guillain-Barré syndrome (OR, 95% CI = 2.53, 1.82–3.51), freezing (6.66, 3.12–14.22), cluster headache (1.53, 1.28–1.84), migraine (1.23,1.17–1.30), postural dizziness (1.24,1.13–1.37), tremor (2.86, 2.68–3.05), headache (1.40, 1.38–1.43), paresthesia (1.11, 1.06–1.16), delirium (1.85, 1.45–2.36), hallucination (2.20, 1.82–2.66), poor quality sleep (1.53, 1.26–1.85), and nervousness (1.54, 1.26–1.89) Reactions less frequently reported with ChAdOx1 than with BNT162b2 were Bell’s palsy (0.47, 0.41–0.55), anosmia (0.58, 0.47–0.71), facial paralysis (0.35, 0.29– 0.41), dysgeusia (0.68, 0.62–0.73), presyncope (0.48, 0.42–0.55), syncope (0.63, 0.58–0.67), and anxiety (0.75 (0.67–0.85). Conclusion: Neurological and psychiatric AEFIs were relatively infrequent, but each vaccine was associated with a distinctive toxic profile. Plain Language Summary We examined reports on adverse neurological and psychiatric effects following immunization with BNT162b2 (Pfizer-BioNTech) and ChAdOx1 (Oxford-AstraZeneca) for COVID-19 to the United Kingdom Medicines and Healthcare products Regulatory Agency between 9 December 2020 and 30 June 2021. Adverse effects following immunization (AEFIs) were relatively infrequent. Compared to BNT162b2, Guillain-Barré syndrome, freezing phenomenon, cluster headache, migraine, postural dizziness, tremor, headache, paresthesia, delirium, hallucination, poor quality sleep, and nervousness were more frequently reported for ChAdOx1. Reactions less frequently reported for ChAdOx1 than for BNT162b2 were Bell’s palsy, anosmia, facial paralysis, dysgeusia, presyncope, syncope, and anxiety.

  • English
    Authors: 
    Chen, Dongxuan; Lau, Yiu-Chung; Xu, Xiao-Ke; Wang, Lin; Du, Zhanwei; Tsang, Tim K.; Wu, Peng; Lau, Eric H. Y.; Wallinga, Jacco; Cowling, Benjamin J.; +1 more
    Publisher: Nature Publishing Group UK
    Country: United Kingdom
  • Open Access English
    Authors: 
    Asadpour, Faraz;
    Country: Canada

    Persons with intellectual and developmental disabilities (IDD) are found to be at a greater risk for social isolation during COVID-19 pandemic. While existing literature has examined the challenges faced by persons with IDD, there is a dearth of research that addresses the access and usage of digital technologies by persons with IDD as a solution to stay socially connected during the pandemic. This study therefore investigated the access to and use of digital technologies such as the internet in relation to the risk of social isolation experienced by persons with mild intellectual disabilities ID (with or without developmental disabilities) during the COVID-19 Pandemic in Manitoba. Additionally, barriers to the usage of online technology were explored. Data for a sample of 39 adults were collected using an online survey questionnaire, and phone interviews. The key variables in this study are internet use, access to an electronic device, barriers to the internet usage, loneliness, and social isolation. Loneliness was measured using the Revised UCLA (University of California, Los Angeles) Loneliness Scale. To measure social isolation, the MSNA-ID (Maastricht Social Network Analysis – Intellectual Disabilities) tool was used. The study utilized both descriptive and inferential analyses to address the research objectives. We found that the majority of the study participants (89.5%), had access to the internet and possessed some form of electronic devices for online connection. The most commonly used devices were smartphones, desktop computers, and tablets. The majority of the study participants (67.6%) who had access to the internet and an electronic device used the internet for social connection during the COVID-19 pandemic. The majority of the study participants (53.8%) perceived that their internet usage made them feel less isolated. The use of the internet was associated with a feeling of less isolation. The results further revealed the most prevalent barriers to the usage of the internet as reported by the study participants. The cost of internet service/equipment (20.6%), having access to the internet elsewhere (17.6%), difficulty in using the internet (14.7%), and safety concerns (14.7%) were the most commonly barriers reported by the study participants.

  • English
    Authors: 
    Pachankis, Yang;
    Country: Germany

    Introduction: The research was conducted during the COVID-19 (SARS-CoV-2) lockdown measures of People’s Republic of China (PRC) with a history & continuation of nuclear proliferation, current electronic warfare, metallic pollution from military heavy industry, and actinic radiation pollutants from chip production. Apart from the biomedical harm sources, the purposes behind the source productions such as chips have been the sources of psychological tortures in neuro-cognitive warfare. The research adopted a human security paradigm primarily in mainland China with multilateral and global implications. Methodology: The research was conducted with the pressure of human trafficking conducted by the PRC. It counteracts the PRC’s disinformation with empirical research, analysis, and psychotherapeutic approaches. The meta-analysis demonstrates that PRC’s declared pandemic responses in fact have not contributed to the positive duties in protecting the public’s right to health, and on the contrary, its accumulated environmental determinants along with power intentions only worsened the public’s autonomous selfceare and mutual assistance responses in the public health situations. Results: The environmental factors in PRC substantially undermine the referential values of biomedical data in international settings, and if applicable, biomedical products export in the global supply chain. Genetic technologies based on applied research in telomerase must have thorough assessments in their impacts on telomeres consumption. Renormalization from and further research into nuclear proliferation and environmental determinants is the only way to improve public health. The PRC has never fulfilled any duties to the liberal institutions nor the territorial civil society. Military intervention and peacekeeping are necessary for PRC’s judicial independence.

  • Open Access English
    Authors: 
    Scherer, Ronny; Siddiq, Fazilat; Howard, Sarah K.; Tondeur, Jo;

    In the present study, we tested the common assumption that teachers with more experience consider themselves better prepared for online teaching and learning (OTL). Utilizing the data from a survey of 366 higher-education teachers from Portugal at the beginning of the COVID-19 pandemic in 2020, we performed structural equation modeling to quantify the experience-readiness relationship. The survey contained an assessment of teachers' OTL readiness which was measured by their perceptions of the institutional support, online teaching presence, and TPACK self-efficacy. In contrast to the linearity assumption “the more experienced, the better prepared”, we found robust evidence for a curvilinear relationship. Teachers’ readiness for OTL increased first and then decreased with more experience—this applied especially to the self-efficacy dimension of readiness. Further analyses suggested that the experience-readiness relationship does not only exist at the level of aggregated constructs but also at the level of indicators, that is, specific areas of knowledge, teaching, and support. We argue that both novice and experienced teachers in higher education could benefit from experience-appropriate, pedagogical, and content-related support programs for OTL.

  • English
    Authors: 
    Ozili, Peterson K.;
    Country: Germany

    This paper analyse the looming COVID-19 global debt crisis. The high debt incurred during the pandemic period by many countries combined with tightening global financial conditions such as increase in interest rate can trigger a global debt crisis for heavily indebted countries. I suggest some actions to be taken by richer countries, heavily indebted countries and multilateral organisations to mitigate the looming COVID-19 global debt crisis. Richer countries who are creditors to poor countries should consider debt forgiveness, interest repayment holidays, debt-forgreen swap and other debt relief options. Multilateral organisations should allow affected members to draw on their contributory fund, they should support the G20 Debt Service Suspension Initiative, and engage in debt forgiveness advocacy. Heavily indebted countries should restructure their debt, rebalance policy priorities, focus on alternatives to borrowing, manage their level of debt, and find better ways to manage shocks and crises.

  • Open Access English
    Authors: 
    Julesz Máté;
    Country: Hungary
  • Closed Access English
    Authors: 
    Sequeiros, José; Pereira, Maria Teresa Ribeiro; Oliveira, Marisa; Ferreira, Fernanda A.;
    Country: Portugal

    Available studies and reports, as well as real-time experiences, attest to profound, extensive, long-lasting effects on the supply chain caused by the pandemic. It is thus paramount to rethink the supply chain for medication and health care supplies to build a more resilient and adaptable management process. Data obtained from the NHS portal monthly reports from January 2017 to August 2020 – indicates that at the hospital level the impact was felt the most on the scheduling of medical appointments and prescriptions. Two forecasting methods were selected for this study: Simple Linear Regression and Holt-Winters with the trend and additive seasonality. There was a change in the behavior of hospital patients in the first year of COVID-19 pandemics. This change was shown in two main indicators, the number of hospital consultations and medication expenses. This changed behavior resulted in a decrease in demand for scheduled hospital services, 1.9M less than would be expected under normal conditions, and a foreseeable increase of €432M in the consumption of medicines in the last quarter of 2020, €103M more than in the same period. from the previous year.

Send a message
How can we help?
We usually respond in a few hours.