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365 Research products, page 1 of 37

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  • Open Access English
    Authors: 
    Lucinde, Ruth Khadembu; Abdi, Abdirahman; Orindi, Benedict; Mwakio, Stella; Gathuri, Henry; Onyango, Edwin; Chira, Salome; Ogero, Morris; Isaaka, Lynda; Shangala, Jimmy; +32 more
    Publisher: Zenodo
    Project: WT | Core Support for the East... (203077)

    These files contain the SPIRIT checklist and study flow diagram for the SONIA Trial. This trial is a pragmatic randomized controlled trial of standard care versus steroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals.

  • Other research product . Other ORP type . 2022
    Open Access Japanese
    Authors: 
    Jolyne Cujoh;
    Publisher: Zenodo
    Project: WT | N-myristoyl transferase a... (087792), WT | N-myristoyl transferase a... (087792)

    ギャンブルは、今も昔も人を惹きつける魅力があります。ギャンブルのような感覚は、言葉では言い表せません。その魔法のような効果を体験するまでは、それが何であるかはわからないのです。薬のことです。トランプが好きな人、クラップスが好きな人、スロットマシンが好きな人、大金を獲得して突然金持ちになることを期待してカジノに行かない生活は考えられません。カジノ」という言葉自体は、イタリア語で「あまり大きな家ではない」と訳すことができる。リッチなカジノハウスやサロンは、世界のさまざまな都市で見かけることができます。そして、アメリカのラスベガスは、一般的にすべてのギャンブラー、プレーヤー、運命論者のメッカと呼ばれることができます。多くの偉人が金のためにギャンブルを好んだ。一瞬にして財を成し、一瞬にして失う、魅力的なストーリーがいかに多いことか。A・ショーペンハウアーは、「富は海水のようなもので、飲めば飲むほど喉が渇く」と言いました。 しかし、世界は立ち止まってはいない。コンピュータと人工知能の時代である情報技術は、今、私たちを取り巻く環境を変え、人類を変えようとしています。私たちの生活がいろいろな意味で簡素化され、情報の伝達速度が以前は夢にも思わなかったほど速くなったのは、インターネット、ワールドワイドウェブの出現のおかげであろう。 また、インターネットのおかげで、オンラインカジノができるようになりました。自宅で、お気に入りのパジャマを着て、徹夜で、あるいは出勤前の早朝に、パソコンから離れることなく、例えば、https://qyto.com/ja/casino/casinodays/、お金を払ってスロットマシンをプレイすることが可能になったのです。小さな額から途方もない額まで賭けて、勝って、負けて、その興奮を味わってください。私たちの世界では、今やバーチャルな生活とリアルな生活を切り離すことは困難になっています。今では、インターネットに興味のある人なら、すぐに自分の好みのゲームを見つけることができるほど、技術の規模と専門性が高まっています。カードポーカー、ブラックジャック、ルーレット、スロットマシン(ゲームとテーマの選択肢は想像を絶する)など、多種多様なゲームが用意されています。 ギャンブルのあるサイトへの訪問者は、それぞれある望みを叶えることが重要です。例えば、誰もがインターネットフォーラムのレビューに注目し、優れた顧客サポートと高速ペイアウトは、高いボーナスと、もちろん、グラフィックデザインが重要になります。このインターネットサービスを利用するユーザーは、興味のあるゲームの各種大会やコンペティションに興味を持つことでしょう。

  • Open Access
    Authors: 
    Kujawa, Aaron;
    Publisher: Zenodo
    Project: WT , UKRI | Wellcome EPSRC Centre for... (NS/A000050/1), UKRI | Wellcome EPSRC Centre for... (NS/A000049/1), WT , UKRI | Wellcome EPSRC Centre for... (NS/A000050/1), UKRI | Wellcome EPSRC Centre for... (NS/A000049/1)

    These are zipped folders containing the model weights, log files, and figures related to the training and inference of vestibular schwannoma segmentations from MRI. The folders correspond to the output folders of the MONAI-based segmentation tool provided at https://github.com/KCL-BMEIS/VS_Seg

  • Open Access English
    Authors: 
    William T Clarke; Mark Chiew;
    Publisher: Zenodo
    Project: WT | Wellcome Centre for Integ... (203139), UKRI | Robust 3D functional imag... (EP/T013133/1), WT | Exploring the role of inh... (102584), WT | Wellcome Centre for Integ... (203139), UKRI | Robust 3D functional imag... (EP/T013133/1), WT | Exploring the role of inh... (102584)

    Data and analysis code to accompany the publication Uncertainty in denoising of MRSI using low rank methods Clarke WT, Chiew M. Uncertainty in denoising of MRSI using low-rank methods. Magnetic Resonance in Medicine 2022;87:574–588 doi: 10.1002/mrm.29018. This submission is hosted and developed on the Wellcome Centre for Integrative Neuroimaging GitLab.

  • Open Access English
    Authors: 
    Aisyah, Dewi; Story, Alistair; Kremyda-Vlachou, Myrto; Kozlakidis, Zisis; Shallcross, Laura; Hayward, Andrew;
    Publisher: Zenodo
    Project: WT | InfeCtion respONse throug... (098608), WT | InfeCtion respONse throug... (098608)

    Background: Injecting drugs substantially increases the risk of hepatitis C virus (HCV) infection and is common in vulnerable population groups, such as the homeless and prisoners. Capturing accurate data on relative genotype distribution within these groups is essential to inform strategies to reduce HCV transmission. The aim of this study was to utilize a next-generation whole-genome sequencing method recently validated by Public Health England, in order to produce near complete HCV genomes. This questionnaire was provided to all individual who consented for their participation to the study.

  • Open Access English
    Authors: 
    Binato, Joanna Almeida;
    Country: Portugal
    Project: WT

    Introdução: A rotina de acompanhamento dos elementos dentários e a evolução da dentição incluem fotografias, radiografias e cefalometria lateral. Estes, no entanto, fornecem apenas uma representação bidimensional (2D) das estruturas dentárias e ósseas e podem levar à perda de dados, sem considerar as diferenças de largura, simetria e forma facial. A tecnologia tridimensional (3D) apresenta inúmeras vantagens, onde os aspectos referentes às estruturas dentárias podem ser visualizados em tamanho real, através de diferentes planos e angulações. Objetivos O objetivo deste estudo é apresentar uma análise tridimensional para localização dos elementos dentários, observando suas dimensões, angulações, posições espaciais e relação com o osso basal, em um estudo piloto utilizando o canino superior permanente em desenvolvimento. Materiais e Métodos: Os dados foram coletados por tomografia computadorizada de 30 crianças, de ambos os sexos, em dentição mista. O software utilizado permitiu a criação de uma análise individual e bilateral, onde as medidas propostas foram obtidas tridimensionalmente. Resultados: Esta análise cefalométrica foi composta por pontos, linhas e planos localizados nas estruturas anatômicas de interesse para a obtenção da posição exata do dente escolhido. Esta análise pode ser feita para qualquer elemento dental, esteja em erupção ou não na cavidade oral. Os pontos de referência localizados no canino superior permanente são comuns a todos os dentes. As linhas e planos dessa análise foram gerados por pontos de referência determinados nos ossos da face, completamente reprodutíveis em qualquer paciente. Conclusões: Como a tomografia substituiu as radiografias convencionais, o surgimento de novos pontos anatômicos e novas análises em 3D é natural, mais confiável e inevitável, com o objetivo de substituir as que foram utilizadas em 2D. Introduction Accompanying routine of the evolution of the dentition include photographs, radiographs, and lateral cephalogram. These, however, provide only a bidimensional representation of the dental and bone structures and it can lead to loss of data, not considering the differences of width, symmetry and facial form. The three-dimensional technology presents countless advantages, where dental structures can be visualised in real size, through different planes and angulations. Objectives The aim of this study is to present a three-dimensional analysis for locate the dental elements, observing their spatial positions and relation with the basal bone, in a pilot study using the developing upper permanent canine. Materials and Methods The data was collected through computerised tomography of 30 children, on mixed dentition. The software used allowed the creation of an individual and bilateral analysis where the proposed measures were obtained threedimensionally. Results This cephalometric analysis was composed by points, lines and planes for the obtainment of the position of the chosen tooth. This can be done for any dental element, whether it is erupted or not into oral cavity. The landmarks located on the upper permanent canine are common to all teeth. The lines and planes on this analysis were generated by landmarks determined on facial bones completely reproducible on any patient. Conclusions As the tomography came to substitute the conventional radiographs, the appearance of new anatomic landmarks and new 3D analysis is natural, more reliable and inevitable with the aim to substitute the ones that have been used on 2D.

  • Open Access English
    Authors: 
    Van Hoving, Daniel J;
    Publisher: Zenodo
    Project: WT | Centre for Infectious Dis... (203135), WT | Defining interventions to... (098316), WT | Centre for Infectious Dis... (203135), WT | Defining interventions to... (098316)

    Code (R) for algorithm of rapid diagnosis of HIV-associated tuberculosis in the emergency centre

  • Open Access
    Authors: 
    Van Hoving, Daniel J;
    Publisher: Zenodo
    Project: WT | Centre for Infectious Dis... (203135), WT | Defining interventions to... (098316), WT | Centre for Infectious Dis... (203135), WT | Defining interventions to... (098316)

    Case report form for the study entitled 'An evidence-based algorithm for the rapid diagnosis of TB in HIV-infected patients presenting to emergency centres'.

  • Open Access English
    Authors: 
    Van Hoving, Daniel J;
    Publisher: Zenodo
    Project: WT | Centre for Infectious Dis... (203135), WT | Defining interventions to... (098316), WT | Centre for Infectious Dis... (203135), WT | Defining interventions to... (098316)

    TRIPOD checklist for manuscript entitled 'A multi-parameter diagnostic clinical decision tree for the rapid diagnosis of tuberculosis in HIV-positive patients presenting to an emergency centre'.

  • French
    Authors: 
    Adema, janneke; Clément, Alexandre; Nominé, Jean-François;
    Publisher: HAL CCSD
    Country: France
    Project: WT

    Ce document est la traduction française d'un rapport de Knowledge Exchange initialement publié en juin 2019 sous le titre "Towards a Roadmap for Open Access Monographs" (DOI: 10.5281/zenodo.3238545); Ce rapport présente les principales conclusions et recommandations issues de l'atelier de consensus entre acteurs organisé par Knowledge Exchange sur les monographies et l’accès ouvert (Stakeholder Workshop on Open Access and Monographs) qui s'est tenu à Bruxelles en novembre 2018.Cette manifestation de deux jours s'est déroulée de la façon suivante : introduction présentant l'état des lieux des monographies en accès ouvert, suivie par des discussions entre bailleurs de fonds et éditeurs ainsi qu'une sélection d'ateliers visant à explorer, de façon approfondie, la manière dont nous pouvons soutenir les monographies en accès ouvert : de l'engagement des auteurs à la mise en place de suivis et de politiques, en passant par l'infrastructure technique. L'objectif de cet atelier était de souligner l'importance des monographies en tant que forme de diffusion dans le paysage de la publication en accès ouvert et d'encourager la collaboration et le partage des meilleures pratiques en la matière. Fondé sur lesrésultats de cet atelier, ce rapport comporte un ensemble de bonnes pratiques et de recommandations à l'intention des différents acteurs concernés afin de définir les prochaines étapes menant à une feuille de route européenne à l'égard des monographies en accès ouvert.

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