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9 research outcomes, page 1 of 1
  • publication . Article . 2021
    Closed Access
    Authors:
    Rasha Khaddaj; Muriel Mari; Stéphanie Cottier; Fulvio Reggiori; Roger Schneiter;
    Persistent Identifiers
    Publisher: The Company of Biologists
    Project: SNSF | Lipid Storage, Binding, a... (31003A_173003), EC | PRONKJEWAIL (713660)

    ABSTRACT Lipid droplets (LDs) are globular subcellular structures that store neutral lipids. LDs are closely associated with the endoplasmic reticulum (ER) and are limited by a phospholipid monolayer harboring a specific set of proteins. Most of these proteins associate...

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  • publication . Article . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Landi, Alessia; Mari, Muriel; Kleiser, Svenja; Wolf, Tobias; Gretzmeier, Christine; Wilhelm, Isabel; Kiritsi, Dimitra; Thünauer, Roland; Geiger, Roger; Nyström, Alexander; ...
    Publisher: Life Science Alliance, LLC
    Project: EC | LEC&LIP2INVADE (282105), EC | DRIVE (765912), NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660)

    Lectins are glycan-binding proteins with no catalytic activity and ubiquitously expressed in nature. Numerous bacteria use lectins to efficiently bind to epithelia, thus facilitating tissue colonisation. Wounded skin is one of the preferred niches for Pseudomonas aerugi...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian;
    Publisher: Rockefeller University Press
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | The role of autophagy in ... (2300175628)

    Autophagy is a catabolic pathway that delivers intracellular material to the mammalian lysosomes or the yeast and plant vacuoles. The final step in this process is the fusion of autophagosomes with vacuoles, which requires SNARE proteins, the homotypic vacuole fusion an...

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  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Wirz, Yannick; Meier, Marc A.; Bouadma, Lila; Luyt, Charles E.; Wolff, Michel; Chastre, Jean; Tubach, Florence; Schroeder, Stefan; Nobre, Vandack; Annane, Djillali; ...
    Persistent Identifiers
    Project: EC | PRONKJEWAIL (713660)

    Background The clinical utility of serum procalcitonin levels in guiding antibiotic treatment decisions in patients with sepsis remains unclear. This patient-level meta-analysis based on 11 randomized trials investigates the impact of procalcitonin-guided antibiotic the...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Gómez-Sánchez, Rubén; Rose, Jaqueline; Guimarães, Rodrigo; Mari, Muriel; Papinski, Daniel; Rieter, Ester; Geerts, Willie J.; Hardenberg, Ralph; Kraft, Claudine; Ungermann, Christian; ...
    Project: FWF | Architecture and function... (P 25522), EC | AutophagosomeSealing (655027), FWF | Mechanisms and hierarchy ... (P 28113), NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | The role of autophagy in ... (2300175628)

    The autophagy-related (Atg) proteins play a key role in the formation of autophagosomes, the hallmark of autophagy. The function of the cluster composed by Atg2, Atg18, and transmembrane Atg9 is completely unknown despite their importance in autophagy. In this study, we...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Mauthe, Mario; Orhon, Idil; Rocchi, Cecilia; Zhou, Xingdong; Luhr, Morten; Hijlkema, Kerst-Jan; Coppes, Robert P.; Engedal, Nikolai; Mari, Muriel; Reggiori, Fulvio;
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Macroautophagy/autophagy is a conserved transport pathway where targeted structures are sequestered by phagophores, which mature into autophagosomes, and then delivered into lysosomes for degradation. Autophagy is involved in the pathophysiology of numerous diseases and...

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  • research data . 2018
    Authors:
    Mauthe, Mario; Idil Orhon; Rocchi, Cecilia; Xingdong Zhou; Luhr, Morten; Kerst-Jan Hijlkema; Coppes, Robert P.; Engedal, Nikolai; Mari, Muriel; Reggiori, Fulvio;
    Publisher: Taylor & Francis
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Macroautophagy/autophagy is a conserved transport pathway where targeted structures are sequestered by phagophores, which mature into autophagosomes, and then delivered into lysosomes for degradation. Autophagy is involved in the pathophysiology of numerous diseases and...

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  • other research product . Other ORP type . 2017
    Open Access English
    Authors:
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Yingying Cong; Pauline Verlhac; Fulvio Reggiori;
    Publisher: MDPI AG
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

    Add to ORCIDorcid
9 research outcomes, page 1 of 1