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  • Other research product . Other ORP type . 2023
    Open Access English
    Authors: 
    Joe Clark;
    Publisher: Zenodo
    Project: WT | Other (CC0103)

    Landscaping is a popular industry in Dubai and there are many landscape companies to choose from. But what sets the best landscaping companies apart from the rest? The answer lies in their ability to properly manage their projects. In this blog, we will discuss how landscape companies in Dubai manage their projects properly and why it is important for them to do so. Planning Ahead The first step to any successful project management is planning ahead. From creating an initial budget and timeline to outlining the scope of the project, proper planning ensures that no detail is overlooked during the course of the project. This also allows you to create realistic expectations for both yourself and your clients, as well as ensuring that all stakeholders are on board with the plan. Managing Resources Efficiently Another key element of proper project management is managing resources efficiently. Landscape companies in Dubai have access to a wide range of tools, materials, and personnel that can be used for their projects. It’s important for these companies to make sure they are using their resources effectively and efficiently by factoring in costs and availability when making decisions about which materials or personnel should be used for a particular project. Maintaining Quality Control Finally, landscape companies need to maintain quality control throughout each stage of their projects. This includes hiring qualified professionals who have experience working with plants or outdoor spaces, as well as conducting regular inspections throughout the course of the project to ensure everything meets quality standards before completion. By doing this, landscape companies in Dubai can ensure that their projects are completed successfully and exceed client expectations every time. Project management is an essential part of any successful business venture—especially when it comes to landscaping services in Dubai. From creating an initial budget and timeline to managing resources efficiently and maintaining quality control throughout each stage of the project, proper planning and execution can make all the difference between success and failure when it comes to completing a landscaping job on time and within budget. With careful attention paid at every step of the way, landscape companies in Dubai can ensure that they deliver exceptional results every time!

  • Open Access English
    Authors: 
    Lucinde, Ruth Khadembu; Abdi, Abdirahman; Orindi, Benedict; Mwakio, Stella; Gathuri, Henry; Onyango, Edwin; Chira, Salome; Ogero, Morris; Isaaka, Lynda; Shangala, Jimmy; +32 more
    Publisher: Zenodo
    Project: WT | Core Support for the East... (203077)

    These files contain the SPIRIT checklist and study flow diagram for the SONIA Trial. This trial is a pragmatic randomized controlled trial of standard care versus steroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals.

  • Other research product . Other ORP type . 2022
    Open Access Japanese
    Authors: 
    Jolyne Cujoh;
    Publisher: Zenodo
    Project: WT | N-myristoyl transferase a... (087792)

    ギャンブルは、今も昔も人を惹きつける魅力があります。ギャンブルのような感覚は、言葉では言い表せません。その魔法のような効果を体験するまでは、それが何であるかはわからないのです。薬のことです。トランプが好きな人、クラップスが好きな人、スロットマシンが好きな人、大金を獲得して突然金持ちになることを期待してカジノに行かない生活は考えられません。カジノ」という言葉自体は、イタリア語で「あまり大きな家ではない」と訳すことができる。リッチなカジノハウスやサロンは、世界のさまざまな都市で見かけることができます。そして、アメリカのラスベガスは、一般的にすべてのギャンブラー、プレーヤー、運命論者のメッカと呼ばれることができます。多くの偉人が金のためにギャンブルを好んだ。一瞬にして財を成し、一瞬にして失う、魅力的なストーリーがいかに多いことか。A・ショーペンハウアーは、「富は海水のようなもので、飲めば飲むほど喉が渇く」と言いました。 しかし、世界は立ち止まってはいない。コンピュータと人工知能の時代である情報技術は、今、私たちを取り巻く環境を変え、人類を変えようとしています。私たちの生活がいろいろな意味で簡素化され、情報の伝達速度が以前は夢にも思わなかったほど速くなったのは、インターネット、ワールドワイドウェブの出現のおかげであろう。 また、インターネットのおかげで、オンラインカジノができるようになりました。自宅で、お気に入りのパジャマを着て、徹夜で、あるいは出勤前の早朝に、パソコンから離れることなく、例えば、https://qyto.com/ja/casino/casinodays/、お金を払ってスロットマシンをプレイすることが可能になったのです。小さな額から途方もない額まで賭けて、勝って、負けて、その興奮を味わってください。私たちの世界では、今やバーチャルな生活とリアルな生活を切り離すことは困難になっています。今では、インターネットに興味のある人なら、すぐに自分の好みのゲームを見つけることができるほど、技術の規模と専門性が高まっています。カードポーカー、ブラックジャック、ルーレット、スロットマシン(ゲームとテーマの選択肢は想像を絶する)など、多種多様なゲームが用意されています。 ギャンブルのあるサイトへの訪問者は、それぞれある望みを叶えることが重要です。例えば、誰もがインターネットフォーラムのレビューに注目し、優れた顧客サポートと高速ペイアウトは、高いボーナスと、もちろん、グラフィックデザインが重要になります。このインターネットサービスを利用するユーザーは、興味のあるゲームの各種大会やコンペティションに興味を持つことでしょう。

  • Open Access
    Authors: 
    Kujawa, Aaron;
    Publisher: Zenodo
    Project: UKRI | Wellcome EPSRC Centre for... (NS/A000050/1), WT , UKRI | Wellcome EPSRC Centre for... (NS/A000049/1)

    These are zipped folders containing the model weights, log files, and figures related to the training and inference of vestibular schwannoma segmentations from MRI. The folders correspond to the output folders of the MONAI-based segmentation tool provided at https://github.com/KCL-BMEIS/VS_Seg

  • Open Access English
    Authors: 
    William T Clarke; Mark Chiew;
    Publisher: Zenodo
    Project: WT | Wellcome Centre for Integ... (203139), UKRI | Robust 3D functional imag... (EP/T013133/1), WT | Exploring the role of inh... (102584)

    Data and analysis code to accompany the publication Uncertainty in denoising of MRSI using low rank methods Clarke WT, Chiew M. Uncertainty in denoising of MRSI using low-rank methods. Magnetic Resonance in Medicine 2022;87:574–588 doi: 10.1002/mrm.29018. This submission is hosted and developed on the Wellcome Centre for Integrative Neuroimaging GitLab.

  • Open Access English
    Authors: 
    Aisyah, Dewi; Story, Alistair; Kremyda-Vlachou, Myrto; Kozlakidis, Zisis; Shallcross, Laura; Hayward, Andrew;
    Publisher: Zenodo
    Project: WT | InfeCtion respONse throug... (098608)

    Background: Injecting drugs substantially increases the risk of hepatitis C virus (HCV) infection and is common in vulnerable population groups, such as the homeless and prisoners. Capturing accurate data on relative genotype distribution within these groups is essential to inform strategies to reduce HCV transmission. The aim of this study was to utilize a next-generation whole-genome sequencing method recently validated by Public Health England, in order to produce near complete HCV genomes. This questionnaire was provided to all individual who consented for their participation to the study.

  • Other research product . Other ORP type . 2021
    Open Access English
    Authors: 
    Kho, S; Qotrunnada, L; Leonardo, L; Andries, B; Wardani, PAI; Fricot, A; Henry, B; Hardy, D; Margyaningsih, NI; Apriyanti, D; +21 more
    Publisher: Massachusetts Medical Society
    Country: United Kingdom
    Project: WT | Reducing malaria morbidit... (099875)
  • Open Access
    Authors: 
    Mukamel, Ronen E.; Handsaker, Robert E.; Sherman, Maxwell A.; Barton, Alison R.; Zheng, Yiming; McCarroll, Steven A.; Loh, Po-Ru;
    Publisher: Zenodo
    Project: NIH | Exploring the role of gen... (5F31MH124393-02), NIH | Investigating the contrib... (5F31HL154537-02), NIH | Revealing somatic genome ... (1DP2ES030554-01), NIH | Exploring the role of gen... (1K25HL150334-01), WT , NIH | Multi-allelic copy number... (5R01HG006855-02), NSF | Totally Geodesic Subvarie... (1939015)

    This package contains the codes and scripts accompanying the manuscript "Protein-coding repeat polymorphisms strongly shape diverse human phenotypes" by Ronen E. Mukamel, Robert E. Hansaker, Maxwell A. Sherman, Alison R. Barton, Yiming Zheng, Steven A. McCarroll, and Po-Ru Loh.

  • Open Access English
    Authors: 
    Maitre, Léa; Julvez, Jordi; López-Vicente, Mònica; Warembourg, Charline; Tamayo-Uria, Ibon; Philippat, Claire; Gützkow, Kristine Bjerve; Guxens, Monica; Andrusaityte, Sandra; Basagaña, Xavier; +21 more
    Project: EC | LIFECYCLE (733206), EC | HELIX (308333), WT | The Born in Bradford (BiB... (101597)
  • Open Access English
    Authors: 
    Dunwell, Thomas L.; Dailey, Simon C.; Ottestad, Anine Larsen; Yu, Jihang; Becker, Philipp W.; Scaife, Sarah; Richman, Susan D.; Wood, Henry M.; Slaney, Hayley; Bottomley, Daniel; +6 more
    Publisher: Nature Research
    Project: WT

    Liquid biopsy testing utilising Next Generation Sequencing (NGS) is rapidly moving towards clinical adoption for personalised oncology. However, before NGS can fulfil its potential any novel testing approach must identify ways of reducing errors, allowing separation of true low-frequency mutations from procedural artefacts, and be designed to improve upon current technologies. Popular NGS technologies typically utilise two DNA capture approaches; PCR and ligation, which have known limitations and seem to have reached a development plateau with only small, stepwise improvements being made. To maximise the ultimate utility of liquid biopsy testing we have developed a highly versatile approach to NGS: Adaptor Template Oligo Mediated Sequencing (ATOM-Seq). ATOM-Seq's strengths and versatility avoid the major limitations of both PCR- and ligation-based approaches. This technology is ligation free, simple, efficient, flexible, and streamlined, and it offers novel advantages that make it perfectly suited for use on highly challenging clinical material. Using reference and clinical materials, we demonstrate detection of known SNVs down to allele frequencies of 0.1% using as little as 20–25 ng of cfDNA, as well as the ability to detect fusions from RNA. We illustrate ATOM-Seq’s suitability for clinical testing by showing high concordance rates between paired cfDNA and FFPE clinical samples.

Advanced search in
Research products
arrow_drop_down
Searching FieldsTerms
Any field
arrow_drop_down
includes
arrow_drop_down
Include:
123 Research products, page 1 of 13
  • Other research product . Other ORP type . 2023
    Open Access English
    Authors: 
    Joe Clark;
    Publisher: Zenodo
    Project: WT | Other (CC0103)

    Landscaping is a popular industry in Dubai and there are many landscape companies to choose from. But what sets the best landscaping companies apart from the rest? The answer lies in their ability to properly manage their projects. In this blog, we will discuss how landscape companies in Dubai manage their projects properly and why it is important for them to do so. Planning Ahead The first step to any successful project management is planning ahead. From creating an initial budget and timeline to outlining the scope of the project, proper planning ensures that no detail is overlooked during the course of the project. This also allows you to create realistic expectations for both yourself and your clients, as well as ensuring that all stakeholders are on board with the plan. Managing Resources Efficiently Another key element of proper project management is managing resources efficiently. Landscape companies in Dubai have access to a wide range of tools, materials, and personnel that can be used for their projects. It’s important for these companies to make sure they are using their resources effectively and efficiently by factoring in costs and availability when making decisions about which materials or personnel should be used for a particular project. Maintaining Quality Control Finally, landscape companies need to maintain quality control throughout each stage of their projects. This includes hiring qualified professionals who have experience working with plants or outdoor spaces, as well as conducting regular inspections throughout the course of the project to ensure everything meets quality standards before completion. By doing this, landscape companies in Dubai can ensure that their projects are completed successfully and exceed client expectations every time. Project management is an essential part of any successful business venture—especially when it comes to landscaping services in Dubai. From creating an initial budget and timeline to managing resources efficiently and maintaining quality control throughout each stage of the project, proper planning and execution can make all the difference between success and failure when it comes to completing a landscaping job on time and within budget. With careful attention paid at every step of the way, landscape companies in Dubai can ensure that they deliver exceptional results every time!

  • Open Access English
    Authors: 
    Lucinde, Ruth Khadembu; Abdi, Abdirahman; Orindi, Benedict; Mwakio, Stella; Gathuri, Henry; Onyango, Edwin; Chira, Salome; Ogero, Morris; Isaaka, Lynda; Shangala, Jimmy; +32 more
    Publisher: Zenodo
    Project: WT | Core Support for the East... (203077)

    These files contain the SPIRIT checklist and study flow diagram for the SONIA Trial. This trial is a pragmatic randomized controlled trial of standard care versus steroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals.

  • Other research product . Other ORP type . 2022
    Open Access Japanese
    Authors: 
    Jolyne Cujoh;
    Publisher: Zenodo
    Project: WT | N-myristoyl transferase a... (087792)

    ギャンブルは、今も昔も人を惹きつける魅力があります。ギャンブルのような感覚は、言葉では言い表せません。その魔法のような効果を体験するまでは、それが何であるかはわからないのです。薬のことです。トランプが好きな人、クラップスが好きな人、スロットマシンが好きな人、大金を獲得して突然金持ちになることを期待してカジノに行かない生活は考えられません。カジノ」という言葉自体は、イタリア語で「あまり大きな家ではない」と訳すことができる。リッチなカジノハウスやサロンは、世界のさまざまな都市で見かけることができます。そして、アメリカのラスベガスは、一般的にすべてのギャンブラー、プレーヤー、運命論者のメッカと呼ばれることができます。多くの偉人が金のためにギャンブルを好んだ。一瞬にして財を成し、一瞬にして失う、魅力的なストーリーがいかに多いことか。A・ショーペンハウアーは、「富は海水のようなもので、飲めば飲むほど喉が渇く」と言いました。 しかし、世界は立ち止まってはいない。コンピュータと人工知能の時代である情報技術は、今、私たちを取り巻く環境を変え、人類を変えようとしています。私たちの生活がいろいろな意味で簡素化され、情報の伝達速度が以前は夢にも思わなかったほど速くなったのは、インターネット、ワールドワイドウェブの出現のおかげであろう。 また、インターネットのおかげで、オンラインカジノができるようになりました。自宅で、お気に入りのパジャマを着て、徹夜で、あるいは出勤前の早朝に、パソコンから離れることなく、例えば、https://qyto.com/ja/casino/casinodays/、お金を払ってスロットマシンをプレイすることが可能になったのです。小さな額から途方もない額まで賭けて、勝って、負けて、その興奮を味わってください。私たちの世界では、今やバーチャルな生活とリアルな生活を切り離すことは困難になっています。今では、インターネットに興味のある人なら、すぐに自分の好みのゲームを見つけることができるほど、技術の規模と専門性が高まっています。カードポーカー、ブラックジャック、ルーレット、スロットマシン(ゲームとテーマの選択肢は想像を絶する)など、多種多様なゲームが用意されています。 ギャンブルのあるサイトへの訪問者は、それぞれある望みを叶えることが重要です。例えば、誰もがインターネットフォーラムのレビューに注目し、優れた顧客サポートと高速ペイアウトは、高いボーナスと、もちろん、グラフィックデザインが重要になります。このインターネットサービスを利用するユーザーは、興味のあるゲームの各種大会やコンペティションに興味を持つことでしょう。

  • Open Access
    Authors: 
    Kujawa, Aaron;
    Publisher: Zenodo
    Project: UKRI | Wellcome EPSRC Centre for... (NS/A000050/1), WT , UKRI | Wellcome EPSRC Centre for... (NS/A000049/1)

    These are zipped folders containing the model weights, log files, and figures related to the training and inference of vestibular schwannoma segmentations from MRI. The folders correspond to the output folders of the MONAI-based segmentation tool provided at https://github.com/KCL-BMEIS/VS_Seg

  • Open Access English
    Authors: 
    William T Clarke; Mark Chiew;
    Publisher: Zenodo
    Project: WT | Wellcome Centre for Integ... (203139), UKRI | Robust 3D functional imag... (EP/T013133/1), WT | Exploring the role of inh... (102584)

    Data and analysis code to accompany the publication Uncertainty in denoising of MRSI using low rank methods Clarke WT, Chiew M. Uncertainty in denoising of MRSI using low-rank methods. Magnetic Resonance in Medicine 2022;87:574–588 doi: 10.1002/mrm.29018. This submission is hosted and developed on the Wellcome Centre for Integrative Neuroimaging GitLab.

  • Open Access English
    Authors: 
    Aisyah, Dewi; Story, Alistair; Kremyda-Vlachou, Myrto; Kozlakidis, Zisis; Shallcross, Laura; Hayward, Andrew;
    Publisher: Zenodo
    Project: WT | InfeCtion respONse throug... (098608)

    Background: Injecting drugs substantially increases the risk of hepatitis C virus (HCV) infection and is common in vulnerable population groups, such as the homeless and prisoners. Capturing accurate data on relative genotype distribution within these groups is essential to inform strategies to reduce HCV transmission. The aim of this study was to utilize a next-generation whole-genome sequencing method recently validated by Public Health England, in order to produce near complete HCV genomes. This questionnaire was provided to all individual who consented for their participation to the study.

  • Other research product . Other ORP type . 2021
    Open Access English
    Authors: 
    Kho, S; Qotrunnada, L; Leonardo, L; Andries, B; Wardani, PAI; Fricot, A; Henry, B; Hardy, D; Margyaningsih, NI; Apriyanti, D; +21 more
    Publisher: Massachusetts Medical Society
    Country: United Kingdom
    Project: WT | Reducing malaria morbidit... (099875)
  • Open Access
    Authors: 
    Mukamel, Ronen E.; Handsaker, Robert E.; Sherman, Maxwell A.; Barton, Alison R.; Zheng, Yiming; McCarroll, Steven A.; Loh, Po-Ru;
    Publisher: Zenodo
    Project: NIH | Exploring the role of gen... (5F31MH124393-02), NIH | Investigating the contrib... (5F31HL154537-02), NIH | Revealing somatic genome ... (1DP2ES030554-01), NIH | Exploring the role of gen... (1K25HL150334-01), WT , NIH | Multi-allelic copy number... (5R01HG006855-02), NSF | Totally Geodesic Subvarie... (1939015)

    This package contains the codes and scripts accompanying the manuscript "Protein-coding repeat polymorphisms strongly shape diverse human phenotypes" by Ronen E. Mukamel, Robert E. Hansaker, Maxwell A. Sherman, Alison R. Barton, Yiming Zheng, Steven A. McCarroll, and Po-Ru Loh.

  • Open Access English
    Authors: 
    Maitre, Léa; Julvez, Jordi; López-Vicente, Mònica; Warembourg, Charline; Tamayo-Uria, Ibon; Philippat, Claire; Gützkow, Kristine Bjerve; Guxens, Monica; Andrusaityte, Sandra; Basagaña, Xavier; +21 more
    Project: EC | LIFECYCLE (733206), EC | HELIX (308333), WT | The Born in Bradford (BiB... (101597)
  • Open Access English
    Authors: 
    Dunwell, Thomas L.; Dailey, Simon C.; Ottestad, Anine Larsen; Yu, Jihang; Becker, Philipp W.; Scaife, Sarah; Richman, Susan D.; Wood, Henry M.; Slaney, Hayley; Bottomley, Daniel; +6 more
    Publisher: Nature Research
    Project: WT

    Liquid biopsy testing utilising Next Generation Sequencing (NGS) is rapidly moving towards clinical adoption for personalised oncology. However, before NGS can fulfil its potential any novel testing approach must identify ways of reducing errors, allowing separation of true low-frequency mutations from procedural artefacts, and be designed to improve upon current technologies. Popular NGS technologies typically utilise two DNA capture approaches; PCR and ligation, which have known limitations and seem to have reached a development plateau with only small, stepwise improvements being made. To maximise the ultimate utility of liquid biopsy testing we have developed a highly versatile approach to NGS: Adaptor Template Oligo Mediated Sequencing (ATOM-Seq). ATOM-Seq's strengths and versatility avoid the major limitations of both PCR- and ligation-based approaches. This technology is ligation free, simple, efficient, flexible, and streamlined, and it offers novel advantages that make it perfectly suited for use on highly challenging clinical material. Using reference and clinical materials, we demonstrate detection of known SNVs down to allele frequencies of 0.1% using as little as 20–25 ng of cfDNA, as well as the ability to detect fusions from RNA. We illustrate ATOM-Seq’s suitability for clinical testing by showing high concordance rates between paired cfDNA and FFPE clinical samples.

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