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21 Research products, page 1 of 3

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  • Other research products
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  • Open Access English
    Authors: 
    Sala, Luca; Bellin, Milena; Mummery, Christine L.;
    Project: WT

    Cardiotoxicity is a severe side effect of drugs that induce structural or electrophysiological changes in heart muscle cells. As a result, the heart undergoes failure and potentially lethal arrhythmias. It is still a major reason for drug failure in preclinical and clin...

  • Open Access English
    Authors: 
    Matzaraki, Vasiliki; Kumar, Vinod; Wijmenga, Cisca; Zhernakova, Alexandra;
    Project: EC | TANDEM (305279), EC | CD-LINK (322698), WT

    In the past 50 years, variants in the major histocompatibility complex (MHC) locus, also known as the human leukocyte antigen (HLA), have been reported as major risk factors for complex diseases. Recent advances, including large genetic screens, imputation, and analyses...

  • Open Access English
    Authors: 
    Deans, Zandra C.; Costa, Jose Luis; Cree, Ian; Dequeker, Els; Edsjo, Anders; Henderson, Shirley; Hummel, Michael; Ligtenberg, Marjolijn J. L.; Loddo, Marco; Machado, Jose Carlos; +12 more
    Project: WT

    The clinical demand for mutation detection within multiple genes from a single tumour sample requires molecular diagnostic laboratories to develop rapid, high-throughput, highly sensitive, accurate and parallel testing within tight budget constraints. To meet this deman...

  • Other research product . Other ORP type . 2016
    Open Access English
    Authors: 
    Druce, Laura; Moslener, Ulf; Gruening, Christine; Pauw, W.P.; Connell, Richenda; Environmental Governance; Environmental Governance;
    Publisher: the United Nations Environment Programme (UNEP)
    Project: WT

    Climate change will alter the conditions that underlie economies. Slow onset changes such as shifting rainfall patterns, increasing temperatures, and coastal intrusion will affect both global as well as national and subnational markets, while rapid onset events such as ...

  • Open Access English
    Authors: 
    Beneš, Jakub; Bulatović, Nataša; Edmond, Jennifer; Knežević, Milica; Lehmann, Jörg; Morselli, Francesca; Zamoiski, Andrei;
    Publisher: CENDARI Project
    Project: WT

    While the acquisition and curation of heterogeneous data in a single repository presents a technical challenge in itself, the ingestion of data into the CENDARI repository also opens up the possibility to process and index them through data extraction, entity recognitio...

  • Other research product . Other ORP type . 2015
    Open Access English
    Authors: 
    Dijk, E.M.S.; Dimitropoulos, Harry; Iatropoulou, Katerina; Foufoulas, Ioannis;
    Publisher: OpenAIRE2020
    Project: EC | OpenAIRE2020 (643410), WT

    This deliverable relates to the work carried out under task T8.3, “Research Impact Services”. The task’s focus is on the development of pilots with selected National funding agencies and infrastructure initiatives in order to serve them with the OpenAIRE research impact...

  • Open Access English
    Authors: 
    Schuyt, T.N.M.;
    Publisher: Maasricht University
    Project: WT
  • Other research product . Other ORP type . 2015
    Open Access English
    Authors: 
    Addink, G.H.; Sub SBR overig; RENFORCE / Regulering en handhaving;
    Publisher: Ministerie van Binnenlandse Zaken en Koninkrijkrelaties
    Project: WT
  • Open Access English
    Authors: 
    Haver, Vincent G.; Verweij, Niek; Kjekshus, John; Fox, Jayne C.; Wedel, Hans; Wikstrand, John; van Gilst, Wiek H.; de Boer, Rudolf A.; van Veldhuisen, Dirk J.; van der Harst, Pim;
    Project: WT

    Background: Recent genome-wide association studies have identified multiple loci that are associated with an increased risk of developing coronary artery disease (CAD). The impact of these loci on the disease severity and prognosis of ischemic heart failure due to CAD i...

  • Other research product . Other ORP type . 2014
    Open Access English
    Authors: 
    van Ditzhuijzen, Jenneke; ten Have, Margreet; de Graaf, Ron; van Nijnatten, Carol; Vollebergh, Wilma; Leerstoel Vollebergh; Youth in Changing Cultural Contexts;
    Project: TUBITAK | Psikoz Benzeri Yaşantı-Ps... (112S476), WT , TUBITAK | Şizofreni ve Diğer Psikot... (107S053), SNSF | Efficacy of transitional ... (32003B-118347)