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24 research outcomes, page 1 of 3
  • publication . Article . 2020
    Open Access
    Authors:
    Reena H. Doshi; Nicole A. Hoff; Anna Bratcher; Patrick Mukadi; Adva Gadoth; Bradly P. Nicholson; Russell A. Williams; Daniel Mukadi; Matthias Mossoko; Joseph Wasiswa; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Background Health care workers (HCW) are more likely to be exposed to Ebola virus (EBOV) during an outbreak compared to people in the general population due to close physical contact with patients and potential exposure to infectious fluids. However, not all w...

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  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Cedar L. Mitchell; Nicholas F. Brazeau; Corinna Keeler; Melchior Kashamuka Mwandagalirwa; Antoinette Tshefu; Jonathan J. Juliano; Steven R. Meshnick;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Background Plasmodium ovale is an understudied malaria species prevalent throughout much of sub-Saharan Africa. Little is known about the distribution of ovale malaria and risk factors for infection in areas of high malaria endemicity. Methods Using the 2013...

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  • publication . Article . 2020
    Open Access
    Authors:
    John Daniel Kelly; Sarah Rae Wannier; Cyrus Sinai; Caitlin A Moe; Nicole A. Hoff; Seth Blumberg; Bernice Selo; Mathais Mossoko; Gerardo Chowell-Puente; James Holland Jones; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Abstract Background Our understanding of the different effects of targeted versus nontargeted violence on Ebola virus (EBOV) transmission in Democratic Republic of the Congo (DRC) is limited. Methods We used time-series data of case counts to compare individuals in Ebol...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Victor Chaumeau; Ladda Kajeechiwa; Bénédicte Fustec; Jordi Landier; Saw Naw Nyo; Saw Nay Hsel; Phabele Phatharakokordbun; Prapan Kittiphanakun; Suphak Nosten; May Myo Thwin; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Project: WT | Eliminating malaria to co... (101148)

    Abstract Background The objective of mass antimalarial drug administration (MDA) is to eliminate malaria rapidly by eliminating the asymptomatic malaria parasite reservoirs and interrupting transmission. In the Greater Mekong Subregion, where artemisinin-resistant Plasm...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Romy Kerber; Eva Lorenz; Sophie Duraffour; Daouda Sissoko; Martin Rudolf; Anna Jaeger; Sekou Ditinn Cisse; Alseny-Modet Camara; Osvaldo Miranda; Carlos M Castro; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | EVIDENT (666100), EC | REACTION (666092)

    In 2015, favipiravir was administered on a compassionate-use basis to patients with Ebola virus disease in Guinea. This study reveals a trend toward improved survival in favipiravir-treated patients; however, the effect of treatment was not statistically significant, ex...

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  • publication . Article . 2018
    Open Access
    Authors:
    Xiaoyan Zhou; Youming Wang; Hualei Liu; Fusheng Guo; Suhail A.R. Doi; Carl Smith; Archie C. A. Clements; John Edwards; Baoxu Huang; Ricardo J. Soares Magalhães;
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Background In this study, we aimed to identify the effect of market-level risk factors on avian influenza (AI) infection in poultry and humans and generate evidence that will inform AI prevention and control programs at live bird markets (LBMs). Methods We performed a s...

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  • publication . Article . 2018
    Open Access
    Authors:
    Jimmy Kapetshi; Hugues Fausther-Bovendo; Cindi R. Corbett; Anders Leung; Kamal Ait-Ikhlef; Justus Nsio; Aaron Aruna; Benoit Kebela Ilunga; Jean-Jacques Muyembe; Pierre Formenty; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)

    Detection of chains of transmission is critical to interrupt Ebola virus (EBOV) outbreaks. For >25 years, quantitative reverse transcription polymerase chain reaction performed on biological fluids has been the reference standard for EBOV detection and identification. I...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Jennifer L. Guthrie; Andy Delli Pizzi; David Roth; Clare Kong; Danielle Jorgensen; Mabel Rodrigues; Patrick Tang; Victoria J. Cook; James C. Johnston; Jennifer L. Gardy;
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: CIHR

    Abstract Background Tuberculosis (TB) in children is often an indicator of recent transmission. Genotyping and whole-genome sequencing (WGS) can enhance pediatric TB investigations by confirming or refuting transmission events. Methods Mycobacterium tuberculosis isolate...

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  • publication . Article . 2018
    Open Access
    Authors:
    Nicole A. Hoff; Patrick Mukadi; Reena H. Doshi; Matthew S. Bramble; Kai Lu; Adva Gadoth; Cyrus Sinai; D’Andre Spencer; Bradley Nicholson; Russell A. Williams; ...
    Persistent Identifiers
    Publisher: eScholarship, University of California
    Project: NIH | University of California ... (5D43TW009343-07), NIH | Serological prevalence of... (5R21AI107420-02)

    Healthcare workers in an area with a previous Ebola outbreak in the Democratic Republic of the Congo exhibited both antibody response and neutralizing capacity to at least 1 Ebola protein, despite never having been diagnosed with Ebola virus disease.

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  • publication . Article . 2018
    Open Access
    Authors:
    Ozkan Aydemir; Mark Janko; Nicholas J. Hathaway; Robert Verity; Melchior Kashamuka Mwandagalirwa; Antoinette Tshefu; Sofonias K. Tessema; Patrick W. Marsh; Alice Tran; Thomas Reimonn; ...
    Publisher: Oxford University Press (OUP)
    Project: NIH | Human copy number polymor... (5R01AI099473-03), NSF | Spatio-Temporal Patterns ... (1339949), UKRI | Genetic data as a signal ... (MR/N01507X/1), NIH | Mentoring in Translationa... (5K24AI134990-02), NIH | Carolina Population Cente... (2P2CHD050924-11), NIH | Medical Scientist Trainin... (5T32GM107000-05), NIH | Diversity and Phenotype o... (1R21AI121465-01A1), NIH | Epidemiological and Spati... (5R01AI107949-03)

    Abstract A better understanding of the drivers of the spread of malaria parasites and drug resistance across space and time is needed. These drivers can be elucidated using genetic tools. Here, a novel molecular inversion probe (MIP) panel targeting all major drug-resis...

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24 research outcomes, page 1 of 3