Quick search
Advanced search in
Field to searchTerm
Add rule
Filters (4)
Download Results
393 research outcomes, page 1 of 40
  • publication . Article . Preprint . Other literature type . 2021
    Open Access English
    Authors:
    Maryam Alqabandi; N. de Franceschi; Nolwenn Miguet; Sourav Maity; Marta Bally; Wouter H. Roos; Winfried Weissenhorn; Patricia Bassereau; Stéphanie Mangenot;
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | INTERACT (751404), ANR | ESCRTfission (ANR-14-CE09-0003), ANR | PSL (ANR-10-IDEX-0001), EC | ESCRT model (751715)

    Abstract Background ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast. In humans, ESCRT-III CHMP2 exists as two isoforms, CHMP2A and CHMP2B, but their physical characteristics have...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Clarisse Uwizeye; Johan Decelle; Pierre-Henri Jouneau; Serena Flori; Benoit Gallet; Jean-Baptiste Keck; Davide Dal Bo; Christine Moriscot; Claire Seydoux; Fabien Chevalier; ...
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), ANR | MoMix (ANR-17-CE05-0029), EC | CORBEL (654248), EC | ChloroMito (833184)

    Nature Communications, 12 (1)

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Agathe Marcelot; Ambre Petitalot; Virginie Ropars; Marie-Hélène Le Du; Camille Samson; Stevens Dubois; Guillaume Hoffmann; Simona Miron; Philippe Cuniasse; Jose Antonio Marquez; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706), EC | iNEXT-Discovery (871037)

    International audience; Barrier-to-autointegration factor (BAF), encoded by the BANF1 gene, is an abundant and ubiquitously expressed metazoan protein that has multiple functions during the cell cycle. Through its ability to cross-bridge two double-stranded DNA (dsDNA),...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Jan Felix; Claire Siebert; Julia Novion Ducassou; Jérôme Nigou; Pierre Garcia; Angélique Fraudeau; Karine Huard; Caroline Mas; Céline Brochier-Armanet; Yohann Couté; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | RespViRALI (789385)

    AbstractFrancisella tularensis is one of the most virulent pathogenic bacteria causing the acute human respiratory disease tularemia. While the mechanisms underlying F. tularensis pathogenesis are largely unknown, previous studies have shown that a F. novicida transposo...

    Add to ORCIDorcid
  • publication . Article . 2021
    Open Access English
    Authors:
    Matthew Jessop; Clarissa Liesche; Jan Felix; Ambroise Desfosses; Megghane Baulard; Virgile Adam; Angélique Fraudeau; Karine Huard; Gregory Effantin; Jean-Philippe Kleman; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | RespViRALI (789385), EC | Chap4Resp (647784)

    Pathogenic and commensal bacteria often have to resist the harsh acidity of the host stomach. The inducible lysine decarboxylase LdcI buffers the cytosol and the local extracellular environment to ensure enterobacterial survival at low pH. Here, we investigate the acid ...

    Add to ORCIDorcid
  • publication . Other literature type . Article . Preprint . 2021
    Open Access
    Authors:
    Christophe Caillat; Guilligay D; Torralba J; Nikolas Friedrich; Nieva Jl; Alexandra Trkola; Chris Chipot; François Dehez; Winfried Weissenhorn;
    Publisher: Cold Spring Harbor Laboratory
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | EAVI2020 (681137)

    The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antib...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access English
    Authors:
    Laurissa Ouaguia; Tania Dufeu-Duchesne; Vincent Leroy; Thomas Decaens; J.-B. Reiser; Eleonora Sosa Cuevas; David Durantel; Jenny Valladeau‐Guilemond; Nathalie Bendriss‐Vermare; Laurence Chaperot; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Abstract Objectives C‐type lectin receptors (CLRs) are key receptors used by DCs to orchestrate responses to pathogens. During infections, the glycan–lectin interactions shape the virus–host interplay and viruses can subvert the function of CLRs to escape antiviral immu...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access
    Authors:
    Thomas Di Mattia; Arthur Martinet; Souade Ikhlef; Alastair G. McEwen; Yves Nominé; Corinne Wendling; Pierre Poussin-Courmontagne; Laetitia Voilquin; Pascal Eberling; Frank Ruffenach; ...
    Persistent Identifiers
    Publisher: EMBO
    Project: ANR | CO-CON (ANR-19-CE44-0003)

    Abstract Organelles are physically connected in membrane contact sites. The endoplasmic reticulum possesses three major receptors, VAP‐A, VAP‐B, and MOSPD2, which interact with proteins at the surface of other organelles to build contacts. VAP‐A, VAP‐B, and MOSPD2 conta...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access English
    Authors:
    L. Carrique; Lionel Ballut; Arpit Shukla; Neelakshi Varma; Resmi Ravi; Sébastien Violot; Bharath Srinivasan; Umesh Tippagondanahalli Ganeshappa; Sonia Kulkarni; Hemalatha Balaram; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group
    Project: ANR | PLASMOPUR (ANR-17-CE11-0032)

    Plasmodium falciparum (Pf) relies solely on the salvage pathway for its purine nucleotide requirements, making this pathway indispensable to the parasite. Purine nucleotide levels are regulated by anabolic processes and by nucleotidases that hydrolyse these metabolites ...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access English
    Authors:
    Dmitrii Zabelskii; Alexey Alekseev; Kirill Kovalev; Vladan Rankovic; Taras Balandin; D. V. Soloviov; Dmitry Bratanov; Ekaterina Savelyeva; Elizaveta Podolyak; Dmytro Volkov; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | OptoHear (670759), ANR | CBH-EUR-GS (ANR-17-EURE-0003), ANR | Viral_Rhodopsins (ANR-19-CE11-0026), ANR | NEWOPTOGENETICSTOOLS (ANR-15-CE11-0029)

    Nucleocytoplasmic Large DNA Viruses (NCLDV) that infect algae encode two distinct families of microbial rhodopsins. Here, the authors characterise two proteins form the viral rhodopsin group 1 OLPVR1 and VirChR1, present the 1.4 Å crystal structure of OLPVR1 and show th...

    Add to ORCIDorcid
393 research outcomes, page 1 of 40