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7,154 research outcomes, page 1 of 716
  • publication . Article . 2021
    Open Access English
    Authors:
    Woo, Anthony,; Gaia, Morgan; Guglielmini, Julien; Da Cunha, Violette; Forterre, Patrick;
    Publisher: HAL CCSD
    Project: EC | EVOMOBIL (340440)

    International audience; Double-stranded DNA viruses of the realm Varidnaviria (formerly PRD1-adenovirus lineage) are characterized by homologous major capsid proteins (MCPs) containing one (kingdom: Helvetiavirae) or two β-barrel domains (kingdom: Bamfordvirae) known as...

  • publication . Article . 2021
    English
    Authors:
    Liu, Junfeng; Soler, Nicolas; Gorlas, Aurore; Cvirkaite-Krupovic, Virginija; Krupovic, Mart; Forterre, Patrick;
    Publisher: HAL CCSD
    Project: EC | EVOMOBIL (340440)

    International audience; Membrane-bound extracellular vesicles (EVs) are secreted by cells from all three domains of life and their implication in various biological processes is increasingly recognized. In this review, we summarize the current knowledge on archaeal EVs ...

  • publication . Preprint . Other literature type . Article . 2021
    Open Access English
    Authors:
    Sébastien Herbert; Léo Valon; Laure Mancini; Nicolas Dray; Paolo Caldarelli; Jerome Gros; Elric Esposito; Spencer L. Shorte; Laure Bally-Cuif; Romain Levayer; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | SYSTEMATICS (322936), EC | PASTEURDOC (665807), EC | CoSpaDD (758457), EC | LIMBCELLDYNAMICS (337635)

    BackgroundQuantitative imaging of epithelial tissues prompts for bioimage analysis tools that are widely applicable and accurate. In the case of imaging 3D tissues, a common pre-processing step consists in projecting the acquired 3D volume on a 2D plane mapping the tiss...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Eva Conde; Romain Bertrand; Bianca Balbino; Jonathan Bonnefoy; Julien Stackowicz; Noémie Caillot; Fabien Colaone; Samir Hamdi; Raïssa Houmadi; Alexia Loste; ...
    Publisher: HAL CCSD
    Project: EC | MYELOSHOCK (616050)

    International audience; Allergic asthma is characterized by elevated levels of IgE antibodies, type 2 cytokines such as interleukin-4 (IL-4) and IL-13, airway hyperresponsiveness (AHR), mucus hypersecretion and eosinophilia. Approved therapeutic monoclonal antibodies ta...

  • publication . Article . 2021
    Open Access English
    Authors:
    Ferrari, Mariana L.; Charova, Spyridoula N.; Sansonetti, Philippe J.; Mylonas, Efstratios; Gazi, Anastasia D.;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | DECRYPT (339579), EC | HOMEOEPITH (232798), EC | EIMID-IAPP (217768)

    Bacterial Type III Secretion Systems (T3SSs) are specialized multicomponent nanomachines that mediate the transport of proteins either to extracellular locations or deliver Type III Secretion effectors directly into eukaryotic host cell cytoplasm. Shigella, the causing ...

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  • publication . Article . 2021
    Restricted English
    Authors:
    Valerie Pezo; Faten Jaziri; Pierre-Yves Bourguignon; Dominique Louis; Deborah Jacobs-Sera; Jef Rozenski; Sylvie Pochet; Piet Herdewijn; Graham F. Hatfull; Pierre-Alexandre Kaminski; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | XNA (320683)

    Bacteriophage genomes harbor the broadest chemical diversity of nucleobases across all life forms. Certain DNA viruses that infect hosts as diverse as cyanobacteria, proteobacteria, and actinobacteria exhibit wholesale substitution of aminoadenine for adenine, thereby f...

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  • publication . Other literature type . Preprint . 2021
    Open Access
    Authors:
    Kim, Dae-Kyum; Weller, Benjamin; Lin, Chung-Wen; Sheykhkarimli, Dayag; Knapp, Jennifer J.; Kishore, Nishka; Sauer, Mayra; Rayhan, Ashyad; Young, Veronika; Marin-de la Rosa, Nora; ...
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | PREPARE (602525), EC | RiPCoN (101003633)

    ABSTRACTKey steps in viral propagation, immune suppression, and pathology are mediated by direct, binary, physical interactions between viral and host proteins. To understand the biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, we gener...

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  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Junfeng Liu; Virginija Cvirkaite-Krupovic; Pierre-Henri Commere; Yunfeng Yang; Fan Zhou; Yulong Shen; Patrick Forterre; Mart Krupovic;
    Publisher: HAL CCSD
    Project: EC | EVOMOBIL (340440)

    International audience; Role of extracellular vesicles in extreme environments Membrane-bound extracellular vesicles (EVs), secreted by cells from all three domains of life, transport various molecules and act as agents of intercellular communication in diverse environm...

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  • publication . Article . 2021
    English
    Authors:
    Lenne, Pierre François; Munro, Edwin; Heemskerk, Idse; Warmflash, Aryeh; Bocanegra-Moreno, Laura; Kishi, Kasumi; Kicheva, Anna; Long, Yuchen; Fruleux, Antoine; Boudaoud, Arezki; ...
    Publisher: HAL CCSD
    Project: ANR | CENTURI (ANR-16-CONV-0001), EC | MECHABLASTO (757557), EC | LIMBCELLDYNAMICS (337635), ANR | DEEP (ANR-11-LABX-0044), EC | MorphoNotch (682161), EC | GROWTHPATTERN (680037), NIH | Time-keeping mechanisms o... (1R01GM122936-01), EC | PASTEURDOC (665807), ANR | AdGastrulo (ANR-19-CE13-0022), EC | FORCASTER (647073)

    International audience; The way in which interactions between mechanics and biochemistry lead to the emergence of complex cell and tissue organization is an old question that has recently attracted renewed interest from biologists, physicists, mathematicians and compute...

  • publication . Article . 2021
    Restricted English
    Authors:
    Jasper B. J. Kamphuis; William P. M. Worrall; Julien Stackowicz; Aurélie Mougel; Emilie Mauré; Eva Conde; Pierre Bruhns; Laurent Guilleminault; Nicolas Gaudenzio; Jinmiao Chen; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | NEMESIS (749629), EC | IMMCEPTION (802041), EC | MYELOSHOCK (616050)

    Taniguchi et al. (Research Articles, 17 July 2020, p. 269) claim that the cytokine interleukin-33 induces accumulation of tumor-associated macrophages expressing the immunoglobulin E receptor FcεRI. Although these findings hold great therapeutic promise, we provide evid...

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7,154 research outcomes, page 1 of 716