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56 research outcomes, page 1 of 6
  • publication . Article . 2021
    Open Access English
    Authors:
    Clarisse Uwizeye; Johan Decelle; Pierre-Henri Jouneau; Serena Flori; Benoit Gallet; Jean-Baptiste Keck; Davide Dal Bo; Christine Moriscot; Claire Seydoux; Fabien Chevalier; ...
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | ChloroMito (833184), EC | CORBEL (654248), ANR | MoMix (ANR-17-CE05-0029)

    Nature Communications, 12 (1)

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  • publication . Preprint . Article . 2021
    English
    Authors:
    Uwizeye, Clarisse; Mars Brisbin, Margaret; Gallet, Benoit; Chevalier, Fabien; LeKieffre, Charlotte; Schieber, Nicole; Falconet, Denis; Wangpraseurt, Daniel; Schertel, Lukas; Stryhanyuk, Hryhoriy; ...
    Publisher: HAL CCSD
    Project: EC | ChloroMito (833184), EC | CORBEL (654248)

    International audience; Endosymbioses have shaped the evolutionary trajectory of life and remain ecologically important. Investigating oceanic photosymbioses can illuminate how algal endosymbionts are energetically exploited by their heterotrophic hosts and inform on pu...

  • publication . Article . 2021
    Open Access English
    Authors:
    Marcelot, Agathe; Petitalot, Ambre; Ropars, Virginie; Le Du, Marie-Hélène; Samson, Camille; Dubois, Stevens; Hoffmann, Guillaume; Miron, Simona; Cuniasse, Philippe; Marquez, Jose Antonio; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT-Discovery (871037), EC | iNEXT (653706)

    International audience; Barrier-to-autointegration factor (BAF), encoded by the BANF1 gene, is an abundant and ubiquitously expressed metazoan protein that has multiple functions during the cell cycle. Through its ability to cross-bridge two double-stranded DNA (dsDNA),...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Matthew Jessop; Clarissa Liesche; Jan Felix; Ambroise Desfosses; Megghane Baulard; Virgile Adam; Angélique Fraudeau; Karine Huard; Gregory Effantin; Jean-Philippe Kleman; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | Chap4Resp (647784), EC | RespViRALI (789385)

    Pathogenic and commensal bacteria often have to resist the harsh acidity of the host stomach. The inducible lysine decarboxylase LdcI buffers the cytosol and the local extracellular environment to ensure enterobacterial survival at low pH. Here, we investigate the acid ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Marco Schiavina; Edoardo Salladini; Maria Grazia Murrali; Giancarlo Tria; Isabella C. Felli; Roberta Pierattelli; Sonia Longhi;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706)

    International audience; Using SAXS and NMR spectroscopy, we herein provide a high-resolution description of the intrinsically disordered N-terminal domain (PNT, aa 1-406) shared by the Nipah virus (NiV) phosphoprotein (P) and V protein, two key players in viral genome r...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Maisonnasse, Pauline; Guedj, Jérémie; Contreras, Vanessa; Behillil, Sylvie; Solas, Caroline; Marlin, Romain; Naninck, Thibaut; Pizzorno, Andres; Lemaitre, Julien; Gonçalves, Antonio; ...
    Publisher: HAL CCSD
    Project: EC | Fight-nCoV (101003555), EC | EVAg (653316), EC | TRANSVAC2 (730964), ANR | IDMIT (ANR-11-INBS-0008)

    International audience; Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic and no antiviral drug or vaccine is yet available for the treatment of this disease1-3. Several clinical studies are ongoing to evaluate the efficacy of repurposed drugs tha...

  • publication . Article . 2020
    Open Access English
    Authors:
    Simon G. P. Funnell; W. E. Dowling; César Muñoz-Fontela; Pierre Stéphane Gsell; Donald E. Ingber; G. A. Hamilton; Leen Delang; Joana Rocha-Pereira; Suzanne J. F. Kaptein; K. H. Dallmeier; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | Lung-on-a-Chip Disease Mo... (1UG3HL141797-01), EC | EVAg (653316), EC | TRANSVAC2 (730964), ANR | IDMIT (ANR-11-INBS-0008)

    International audience; There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This comment...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    K.K. Rasmussen; Andrés Palencia; Anders K. Varming; Habiba El-Wali; Elisabetta Boeri Erba; Martin Blackledge; Karin Hammer; Torsten Herrmann; Mogens Kilstrup; Leila Lo Leggio; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706), EC | ERCSC-CHAIRS-SUP2013 (341400), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Temperate bacteriophages can enter one of two life cycles following infection of a sensitive host: the lysogenic or the lytic life cycle. The choice between the two alternative life cycles is dependent upon a tight regulation of promoters and their cognate regulatory pr...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Aldo R. Camacho-Zarco; Sissy Kalayil; Damien Maurin; Nicola Salvi; Elise Delaforge; Sigrid Milles; Malene Ringkjøbing Jensen; Darren J. Hart; Stephen Cusack; Martin Blackledge;
    Publisher: Nature Publishing Group
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | AvINFLUENZA (796490)

    Avian influenza polymerase undergoes host adaptation in order to efficiently replicate in human cells. Here, the authors use NMR spectroscopy and quantitative ensemble modelling to describe the highly dynamic assemblies formed by the human-adapted or avian-adapted C-ter...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Flaugnatti, Nicolas; Rapisarda, Chiara; Rey, Martial; Beauvois, Solène,; Nguyen, Viet anh; Canaan, Stéphane; Durand, Eric; Chamot‐Rooke, Julia; Cascales, E.; Fronzes, Rémi; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706)

    International audience; The bacterial type VI secretion system (T6SS) is a macromolecular machine that injects effectors into prokaryotic and eukaryotic cells. The mode of action of the T6SS is similar to contractile phages: the contraction of a sheath structure pushes ...

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56 research outcomes, page 1 of 6