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182 research outcomes, page 1 of 19
  • publication . Article . 2021
    Open Access English
    Authors:
    Clarisse Uwizeye; Johan Decelle; Pierre-Henri Jouneau; Serena Flori; Benoit Gallet; Jean-Baptiste Keck; Davide Dal Bo; Christine Moriscot; Claire Seydoux; Fabien Chevalier; ...
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | ChloroMito (833184), EC | CORBEL (654248), ANR | MoMix (ANR-17-CE05-0029)

    Nature Communications, 12 (1)

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Alqabandi, Maryam; de Franceschi, Nicola; Miguet, Nolwenn; Maity, Sourav; Bally, Marta; Roos, Wouter H.; Weissenhorn, Winfried; Bassereau, Patricia; Mangenot, Stéphanie;
    Publisher: Cold Spring Harbor Laboratory
    Project: ANR | ESCRTfission (ANR-14-CE09-0003), EC | INTERACT (751404), EC | ESCRT model (751715), ANR | PSL (ANR-10-IDEX-0001), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Abstract Background ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast. In humans, ESCRT-III CHMP2 exists as two isoforms, CHMP2A and CHMP2B, but their physical characteristics have...

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  • publication . Article . Part of book or chapter of book . 2021
    Restricted English
    Authors:
    Lionel Imbert; Rachel Lenoir-Capello; Elodie Crublet; Alicia Vallet; Rida Awad; Isabel Ayala; Celine Juillan-Binard; Hubert Mayerhofer; Rime Kerfah; Pierre Gans; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | INSTRUCT-ULTRA (731005)

    International audience; The cell-free synthesis is an efficient strategy to produce in large scale protein samples for structural investigations. In vitro synthesis allows for significant reduction of production time, simplification of purification steps and enables pro...

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  • publication . Preprint . Article . 2021
    English
    Authors:
    Uwizeye, Clarisse; Mars Brisbin, Margaret; Gallet, Benoit; Chevalier, Fabien; LeKieffre, Charlotte; Schieber, Nicole; Falconet, Denis; Wangpraseurt, Daniel; Schertel, Lukas; Stryhanyuk, Hryhoriy; ...
    Publisher: HAL CCSD
    Project: EC | ChloroMito (833184), EC | CORBEL (654248)

    International audience; Endosymbioses have shaped the evolutionary trajectory of life and remain ecologically important. Investigating oceanic photosymbioses can illuminate how algal endosymbionts are energetically exploited by their heterotrophic hosts and inform on pu...

  • publication . Article . 2021
    Open Access English
    Authors:
    Marcelot, Agathe; Petitalot, Ambre; Ropars, Virginie; Le Du, Marie-Hélène; Samson, Camille; Dubois, Stevens; Hoffmann, Guillaume; Miron, Simona; Cuniasse, Philippe; Marquez, Jose Antonio; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT-Discovery (871037), EC | iNEXT (653706)

    International audience; Barrier-to-autointegration factor (BAF), encoded by the BANF1 gene, is an abundant and ubiquitously expressed metazoan protein that has multiple functions during the cell cycle. Through its ability to cross-bridge two double-stranded DNA (dsDNA),...

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  • publication . Article . 2021
    English
    Authors:
    Wehbie, Moheddine; Onyia, Kenechi Kanayo; Mahler, Florian; Le Roy, Aline; Deletraz, Anaïs; Bouchemal, Ilham; Vargas, Carolyn; Babalola, Jonathan Oyebamiji; Breyton, Cécile; Ebel, Christine; ...
    Publisher: HAL CCSD
    Project: ANR | FLUOR (ANR-16-CE92-0001), ANR | CBH-EUR-GS (ANR-17-EURE-0003), NSF | IMR-MIP DANSE - Distribut... (0520547), EC | SINE2020 (654000)

    International audience; Two new surfactants, F5OM and F5DM, were designed as partially fluorinated analogues of n-dodecyl-β-D-maltoside (DDM). The micellization properties and the morphologies of the aggregates formed by the two surfactants in water and phosphate buffer...

  • publication . Article . 2021
    Open Access English
    Authors:
    Jan Felix; Claire Siebert; Julia Novion Ducassou; Jérôme Nigou; Pierre Garcia; Angélique Fraudeau; Karine Huard; Caroline Mas; Céline Brochier-Armanet; Yohann Couté; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | RespViRALI (789385)

    AbstractFrancisella tularensis is one of the most virulent pathogenic bacteria causing the acute human respiratory disease tularemia. While the mechanisms underlying F. tularensis pathogenesis are largely unknown, previous studies have shown that a F. novicida transposo...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Matthew Jessop; Clarissa Liesche; Jan Felix; Ambroise Desfosses; Megghane Baulard; Virgile Adam; Angélique Fraudeau; Karine Huard; Gregory Effantin; Jean-Philippe Kleman; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | Chap4Resp (647784), EC | RespViRALI (789385)

    Pathogenic and commensal bacteria often have to resist the harsh acidity of the host stomach. The inducible lysine decarboxylase LdcI buffers the cytosol and the local extracellular environment to ensure enterobacterial survival at low pH. Here, we investigate the acid ...

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  • publication . Preprint . Other literature type . 2021
    Open Access English
    Authors:
    Eleftherios Zarkadas; Hong Zhang; Wensheng Cai; Gregory Effantin; Jonathan Perot; Jacques Neyton; Christophe Chipot; Guy Schoehn; François Dehez; Hugues Nury;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | PentaBrain (637733)

    Inaccurately perceived as niche drugs, antiemetics are key elements of cancer treatment alleviating the most dreaded side effect of chemotherapy. Serotonin 5-HT3 receptor antagonists are the most commonly prescribed class of drugs to control chemotherapy-induced nausea ...

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  • publication . Article . Preprint . 2021
    Open Access
    Authors:
    Christophe Caillat; Delphine Guilligay; Johana Torralba; Nikolas Friedrich; Jose L Nieva; Alexandra Trkola; Christophe J Chipot; François L Dehez; Winfried Weissenhorn;
    Persistent Identifiers
    Publisher: eLife Sciences Publications, Ltd
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | EAVI2020 (681137)

    The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antib...

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182 research outcomes, page 1 of 19