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  • COVID-19

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  • Open Access English
    Authors: 
    Erika Cecon; Julie Dam; Ralf Jockers;
    Publisher: HAL CCSD
    Country: France

    The SARS-CoV-2 coronavirus infects human cells through the interaction of the viral envelope Spike protein (IPR044366) with the human Angiotensin-Converting Enzyme 2 (ACE2), expressed at the surface of target cells. Here, we describe a detailed protocol to measure the b...

  • Open Access English
    Authors: 
    Mehdi Stiti; Guillaume Castanet; Andrew Corber; Marcus Aldén; Edouard Berrocal;
    Publisher: HAL CCSD
    Country: France
    Project: EC | Spray-Imaging (638546)

    To control the evolution of a pandemic such as COVID-19, knowing the conditions under which the pathogen is being transmitted represents a critical issue, especially when implementing protection strategies like social distancing and face masks wearing. For viruses and b...

  • Open Access English
    Authors: 
    Thomas Meunier; Lowiese Desmarets; Simon Bordage; Moussa Bamba; Kévin Hervouet; Yves Rouillé; Nathan François; Marion Decossas; Valentin Sencio; François Trottein; +6 more
    Publisher: HAL CCSD
    Country: France

    International audience; The SARS-CoV-2 outbreak has highlighted the need for broad-spectrum antivirals against coronaviruses (CoVs). Here, pheophorbide a (Pba) was identified as a highly active antiviral molecule against HCoV-229E after bioguided fractionation of plant ...

  • Open Access English
    Authors: 
    Jean-Pierre Alcaraz; Laurence Le Coq; Jérémie Pourchez; Dominique Thomas; Sandrine Chazelet; Isabelle Boudry; Maud Barbado; Sophie Silvent; Claire Dessale; Fabienne Antoine; +25 more
    Publisher: Elsevier
    Country: France

    The need for personal protective equipment increased exponentially in response to the Covid-19 pandemic. To cope with the mask shortage during springtime 2020, a French consortium was created to find ways to reuse medical and respiratory masks in healthcare departments....

  • Open Access
    Authors: 
    David Luque-Paz; Pierre Tattevin; Paul Jaubert; Florian Reizine; Achille Kouatchet; Christophe Camus;
    Publisher: Elsevier BV
    Country: France

    International audience

  • Open Access
    Authors: 
    Luong Ngyen, Liem Binh; Bauer, Rebecca; Lesieur, Zineb; Galtier, Florence; Duval, Xavier; Vanhems, Philippe; Lainé, Fabrice; Tattevin, Pierre; Durier, Christine; Launay, Odile;
    Publisher: Elsevier BV
    Country: France

    International audience; BACKGROUND: Measuring vaccine effectiveness (VE) using real-life data is critical to confirm the effectiveness of licensed vaccine, which could strengthen vaccination adherence. METHODS: We measured VE against adult COVID-19 hospitalization in fi...

  • Open Access English
    Authors: 
    Darielys Santana-Mederos; Rocmira Perez-Nicado; Yanet Climent; Laura Rodriguez; Belinda Sanchez Ramirez; Sonia Perez-Rodriguez; Meybi Rodriguez; Claudia Labrada; Tays Hernandez; Marianniz Diaz; +36 more
    Publisher: HAL CCSD
    Countries: France, Netherlands

    SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer via its receptor-binding domain (RBD) with the host's cellular receptor. Vaccines seek to block this interaction by eliciting neutralizing antibodies, most of which are directed toward ...

  • Open Access
    Authors: 
    Emilie Stoll; Edna Alencar; Tabatha Benitz; Thiago Mota Cardoso; Luiza Dias Flores; Élise Capredon; Ricardo Folhes; João Paulo Soares de Cortes; Lise Tupiassu; Luly Fischer; +1 more
    Publisher: University of Victoria Libraries
    Country: France

    International audience; En Amazonie, l’une des régions du Brésil les plus touchées par l’épidémie de COVID-19, les statistiques épidémiologiques publiées par les autorités brossent un tableau de la crise sanitaire qui interroge, car il ne considère pas ou trop partielle...

  • Open Access English
    Authors: 
    Brice Autier; Juergen Prattes; P. Lewis White; Maricela Valerio; Marina Machado; Jessica S Price; Matthias Egger; Jean-Pierre Gangneux; Martin Hoenigl;
    Publisher: HAL CCSD
    Countries: France, France, United States, France

    International audience; This multicenter study evaluated the IMMY Aspergillus Galactomannan Lateral Flow Assay (LFA) with automated reader for diagnosis of pulmonary aspergillosis in patients with COVID-19 associated acute respiratory failure (ARF) requiring intensive c...

  • Open Access English
    Authors: 
    Hayley MacGregor; Melissa Leach; Grace Akello; Lawrence Sao Babawo; Moses Baluku; Alice Desclaux; Catherine Grant; Foday Kamara; Fred Martineau; Esther Yei Mokuwa; +5 more
    Publisher: HAL CCSD
    Country: France
    Project: WT

    International audience; This article shares findings on COVID-19 in Africa across 2020 to examine concepts and practices of epidemic preparedness and response. Amidst uncertainties about the trajectory of COVID-19, the stages of emergency response emerge in practice as ...