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256 Research products, page 1 of 26

  • Publications
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  • Publication . Conference object . Preprint . 2021
    Open Access English
    Authors: 
    Muhammad Umar B Niazi; Alain Kibangou; Carlos Canudas de Wit; Denis Nikitin; Liudmila Tumash; Pierre-Alexandre Bliman;

    doi: 10.1109/cdc45484.2021.9683300

    Publisher: HAL CCSD
    Country: France
    Project: EC | Scale-FreeBack (694209)

    Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment or vaccine is available. In thi...

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  • Publication . Article . 2021
    Open Access English
    Authors: 
    Samuele Bovo; Giuseppina Schiavo; Anisa Ribani; Valerio Joe Utzeri; Valeria Taurisano; Mohamad Ballan; María Muñoz; Estefania Alves; José Pedro Araújo; Riccardo Bozzi; +22 more

    doi: 10.1038/s41598-021-82956-0

    pmc: PMC7873263

    pmid: 33564056

    Publisher: HAL CCSD
    Countries: Serbia, Italy, France, Spain, Croatia, France
    Project: EC | TREASURE (634476)

    AbstractCoronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that c...

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  • Publication . Article . 2021
    Open Access English
    Authors: 
    Benjamin Gaborit; Bernard Vanhove; Marie-Anne Vibet; Aurélie Le Thuaut; Karine Lacombe; Vincent Dubee; Florence Ader; Virginie Ferre; Eric Vicaut; Jéremie Orain; +14 more

    doi: 10.1186/s13063-021-05132-9

    pmc: PMC7942514

    Publisher: BMC
    Country: France
    Project: EC | BRIGHT (962036)

    Abstract Background Early inhibition of entry and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a very promising therapeutic approach. Polyclonal neutralizing antibodies offers many advantages such as providing immediate immunity, co...

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  • Publication . Article . 2021
    Open Access English
    Authors: 
    Romain Marlin; Véronique Godot; Sylvain Cardinaud; Mathilde Galhaut; Severin Coleon; Sandra Zurawski; Nathalie Dereuddre-Bosquet; Mariangela Cavarelli; Anne-Sophie Gallouet; Pauline Maisonnasse; +28 more

    doi: 10.1038/s41467-021-25382-0

    pmc: PMC8410935

    pmid: 34471122

    Publisher: HAL CCSD
    Country: France
    Project: EC | TRANSVAC2 (730964), EC | EVAg (653316), ANR | IDMIT (ANR-11-INBS-0008)

    Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require additional approaches to currently approved viral vector and mRNA vaccines. Subunit vaccines may have distinct advantages when immunizing vulnerable individuals, children and pregnant wo...

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  • Publication . Preprint . Article . 2021
    Open Access English
    Authors: 
    Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini; Pierre-Yves Boëlle; Vittoria Colizza;

    doi: 10.1038/s41467-021-21249-6 , 10.1101/2020.05.08.20095521

    pmc: PMC7887250

    pmid: 33594076

    Publisher: HAL CCSD
    Country: France
    Project: ANR | DataRedux (ANR-19-CE46-0008), ANR | SPHINx (ANR-17-CE36-0008), EC | MOOD (874850)

    As countries in Europe implement strategies to control the COVID-19 pandemic, different options are chosen regarding schools. Through a stochastic age-structured transmission model calibrated to the observed epidemic in Île-de-France in the first wave, we explored scena...

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  • Publication . Article . Preprint . 2021
    Open Access English
    Authors: 
    Natacha S. Ogando; Priscila El Kazzi; Jessika C. Zevenhoven-Dobbe; Brenda w. Bontes; Alice Decombe; Clara C. Posthuma; Volker Thiel; Bruno Canard; François Ferron; Etienne Decroly; +1 more

    doi: 10.1073/pnas.2108709118 , 10.1101/2021.05.17.444407

    pmc: PMC8670481

    pmid: 34845015

    Publisher: National Academy of Sciences NAS
    Countries: France, Switzerland
    Project: EC | ANTIVIRALS (642434)

    As coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their messenger RNAs (mRNAs), protect them from degradation by cellular 5′ exoribonucleases (ExoNs), and escape innate immune se...

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  • Publication . Article . Conference object . Other literature type . 2021
    Open Access English
    Authors: 
    Writing Committee for the REMAP-CAP Investigators; Estcourt, Lise J; Turgeon, Alexis F; McQuilten, Zoe K; McVerry, Bryan J; Al-Beidh, Farah; Annane, Djillali; Arabi, Yaseen M; Arnold, Donald M; Beane, Abigail; +83 more

    doi: 10.1001/jama.2021.18178

    pmc: PMC8491132

    pmid: 34606578

    handle: 20.500.11820/e7243504-4440-42c4-a086-5c53aadbca74 , 10067/1826300151162165141

    Publisher: HAL CCSD
    Countries: France, France, United Kingdom, Belgium, Netherlands, Netherlands
    Project: EC | PREPARE (602525)

    International audience; Importance: The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive. Objective: To determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19. Design, Set...

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  • Publication . Article . 2021
    Open Access English
    Authors: 
    Nathalie Bajos; François Beck; Nathalie Lydié; Claude Martin; Florence Jusot; Laurence Meyer; Rémy Slama; Josiane Warszawski; Jeanna-eve Franck; Emilie Counil; +9 more

    doi: 10.1136/bmjopen-2021-052888

    pmc: PMC8587531

    Publisher: HAL CCSD
    Country: France
    Project: EC | GENDHI (856478)

    ObjectiveAlthough social inequalities in COVID-19 mortality by race, gender and socioeconomic status are well documented, less is known about social disparities in infection rates and their shift over time. We aim to study the evolution of social disparities in infectio...

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  • Publication . Article . 2021
    Open Access English
    Authors: 
    Marina Serrano-Macia; Jorge Simón; Maria J. Gonzalez-Rellan; Mikel Azkargorta; Naroa Goikoetxea-Usandizaga; Fernando Lopitz-Otsoa; Diego Saenz de Urturi; Rubén Rodríguez-Agudo; Sofia Lachiondo-Ortega; Maria Mercado-Gómez; +21 more

    doi: 10.1016/j.molmet.2021.101275

    pmc: PMC8280515

    pmid: 34153521

    handle: 10347/26654

    Publisher: Elsevier
    Countries: Italy, France, Spain
    Project: EC | LITMUS (777377), EC | UbiCODE (765445)

    Objective Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic fatty liver disease (NAFLD). Herein, we propose to addre...

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  • Publication . Article . 2021
    Open Access English
    Authors: 
    Marion Gransagne; Gabriel Aymé; Sébastien Brier; Gaëlle Chauveau-Le Friec; Véronique Mériaux; Mireille Nowakowski; François Dejardin; Sylvain Levallois; Guilherme D. Melo; Flora Donati; +12 more

    doi: 10.1016/j.jbc.2021.101290

    pmc: PMC8526496

    pmid: 34678315

    Publisher: HAL CCSD
    Country: France
    Project: EC | EVAg (653316)

    International audience; The current COVID-19 pandemic illustrates the importance of obtaining reliable methods for the rapid detection of SARS-CoV-2. A highly specific and sensitive diagnostic test able to differentiate the SARS-CoV-2 virus from common human coronavirus...

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