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48 research outcomes, page 1 of 5
  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Begoña Alburquerque-González; Ángel Bernabé-García; Manuel Bernabé-García; Javier Ruiz-Sanz; Fernando Feliciano López-Calderón; Leonardo Gonnelli; Lucia Banci; Jorge Peña-García; Irene Luque; Francisco José Nicolás; ...
    Persistent Identifiers
    Publisher: MDPI
    Project: EC | CORBEL (654248)

    Fundación Seneca 20988/PI/18 20646/JLI/18

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  • publication . Article . Other literature type . Preprint . 2021
    Open Access English
    Authors:
    Lidia Ruiz; Zuzanna Kaczmarska; Tiago Gomes; Eric Aragón; Carles Torner; Regina Freier; Blazej Baginski; Pau Martin-Malpartida; Natàlia de Martin Garrido; José A. Márquez; ...
    Publisher: Research Network of Computational and Structural Biotechnology
    Project: EC | PREBIST (754558), EC | PROBIST (754510), EC | iNEXT (653706)

    Highlights • MH1 domains of BMP-activated Smads populate a dimer-monomer equilibrium. • Swapping loop1 between BMP- and TGFβ Smads turns dimers into monomers and vice versa. • BMP-responsive genomic regions have a lower average count of motifs than TGFβ ones.

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  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Lucia Gigli; Enrico Ravera; Vito Calderone; Claudio Luchinat;
    Persistent Identifiers
    Publisher: MDPI AG

    Nature has evolved several molecular machineries to promote the formation at physiological conditions of inorganic materials, which would otherwise be formed in extreme conditions. The molecular determinants of this process have been established over the last decade, id...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Iain M Hay; Gareth W. Fearnley; Pablo Rios; Maja Köhn; Hayley J. Sharpe; Janet E. Deane;
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | BIOSTRUCT-X (283570), WT

    Receptor-linked protein tyrosine phosphatases (RPTPs) usually contain an active membrane proximal domain and an inactive pseudophosphatase domain. Here, the authors characterize an RPTP with two pseudophosphatase domains, providing evidence that it may act as a decoy re...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Elena Shumilina; Alessandra Ciampa; Trine Ytrestøyl; Alexander Dikiy;
    Publisher: MDPI
    Project: EC | iNEXT (653706)

    This study aimed to assess the astaxanthin (Ax) accumulation in hepatocytes isolated from farmed Atlantic salmon fed different diets (rich marine, poor, poor with marine phospholipids (MPL) and poor with docosahexaenoic acid (DHA)). Nuclear magnetic resonance (NMR) spec...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Daniela Lalli; Camilla Rosa; Marco Allegrozzi; Paola Turano;
    Persistent Identifiers
    Publisher: Multidisciplinary Digital Publishing Institute

    It is well known that axial coordination of heme iron in mitochondrial cytochrome c has redox-dependent stability. The Met80 heme iron axial ligand in the ferric form of the protein is relatively labile and can be easily replaced by alternative amino acid side chains un...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Alessia Vignoli; Elena Muraro; Gianmaria Miolo; Leonardo Tenori; Paola Turano; Emanuela Di Gregorio; Agostino Steffan; Claudio Luchinat; Giuseppe Corona;
    Persistent Identifiers
    Publisher: MDPI

    HER2-positive breast cancer (BC) represents a heterogeneous cancer disease. In an attempt to identify new stratification models useful for prognosis and therapeutic strategy, we investigated the influence of estrogen receptor (ER) status on the host immune and metabolom...

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  • publication . Article . Other literature type . Preprint . 2020
    Open Access English
    Authors:
    Brian Bockelman; Andrea Ceccanti; Ian Collier; Linda Cornwall; Thomas Dack; Jaroslav Guenther; Mario Lassnig; Maarten Litmaath; Paul Millar; Mischa Sallé; ...
    Persistent Identifiers
    Publisher: EDP Sciences
    Project: EC | EOSCpilot (739563), NSF | S2I2: Institute for Resea... (1836650), EC | AARC2 (730941), EC | EOSC-hub (777536)

    The WLCG Authorisation Working Group was formed in July 2017 with the objective to understand and meet the needs of a future-looking Authentication and Authorisation Infrastructure (AAI) for WLCG experiments. Much has changed since the early 2000s when X.509 certificate...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Abdullah Basoglu; Nuri Baspinar; Leonardo Tenori; Cristina Licari; Erdem Gulersoy;
    Publisher: Taylor & Francis
    Project: EC | iNEXT (653706)

    Background: Displaced abomasum (DA) is a condition of dairy cows that severely impacts animal welfare and causes huge economic losses. Objective: To assess the metabolic status of the disease using metabolomics in serum, urine and liver samples aimed at both water solub...

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  • publication . Article . Preprint . Other literature type . 2019
    Open Access
    Authors:
    Blum, Yannick; Mikelson, Jan; Dobrzyński, Maciej; Ryu, Hyunryul; Jacques, Marc‐Antoine; Jeon, Noo Li; Khammash, Mustafa; Pertz, Olivier;
    Publisher: EMBO
    Project: EC | TRANSVAC2 (730964), SNSF | Understanding single cell... (IZKSZ3_162195)

    Abstract Stimulation of PC‐12 cells with epidermal (EGF) versus nerve (NGF) growth factors (GFs) biases the distribution between transient and sustained single‐cell ERK activity states, and between proliferation and differentiation fates within a cell population. We rep...

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48 research outcomes, page 1 of 5