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8,859 research outcomes, page 1 of 886
  • publication . Article . 2021
    English
    Authors:
    Rachez, Christophe; Legendre, Rachel; Costallat, Mickaël; Varet, Hugo; Yi, Jia; Kornobis, Etienne; Muchardt, Christian;
    Publisher: HAL CCSD
    Project: EC | PASTEURDOC (665807)

    International audience; HP1 proteins are best known as markers of heterochromatin and gene silencing. Yet, they are also RNA-binding proteins and the HP1c/CBX3 family member is present on transcribed genes together with RNA polymerase II, where it regulates cotranscript...

  • publication . Article . 2021
    Open Access English
    Authors:
    Woo, Anthony,; Gaia, Morgan; Guglielmini, Julien; Da Cunha, Violette; Forterre, Patrick;
    Publisher: HAL CCSD
    Project: EC | EVOMOBIL (340440)

    International audience; Double-stranded DNA viruses of the realm Varidnaviria (formerly PRD1-adenovirus lineage) are characterized by homologous major capsid proteins (MCPs) containing one (kingdom: Helvetiavirae) or two β-barrel domains (kingdom: Bamfordvirae) known as...

  • publication . Article . 2021
    English
    Authors:
    Rooy, Marie; Lazarevich, Ivan; Koukouli, Fani; Maskos, Uwe; Gutkin, Boris;
    Publisher: HAL CCSD
    Project: EC | HBP SGA2 (785907)

    International audience; Nicotinic acetylcholine receptors (nAChRs) modulate the cholinergic drive to a hierarchy of inhibitory neurons in the superficial layers of the PFC, critical to cognitive processes. It has been shown that genetic deletions of the various types of...

  • publication . Article . 2021
    English
    Authors:
    Garcia-Garcia, Transito; Poncet, Sandrine; Cuenot, Elodie; Douché, Thibaut; Giai Gianetto, Quentin; Peltier, Johann; Courtin, Pascal; Chapot-Chartier, Marie-Pierre; Matondo, Mariette; Dupuy, Bruno; ...
    Publisher: HAL CCSD
    Project: EC | CLOSPORE (642068)

    International audience; Cell growth and division require a balance between synthesis and hydrolysis of the peptidoglycan (PG). Inhibition of PG synthesis or uncontrolled PG hydrolysis can be lethal for the cells, making it imperative to control peptidoglycan hydrolase (...

  • publication . Article . 2021
    English
    Authors:
    Liu, Junfeng; Soler, Nicolas; Gorlas, Aurore; Cvirkaite-Krupovic, Virginija; Krupovic, Mart; Forterre, Patrick;
    Publisher: HAL CCSD
    Project: EC | EVOMOBIL (340440)

    International audience; Membrane-bound extracellular vesicles (EVs) are secreted by cells from all three domains of life and their implication in various biological processes is increasingly recognized. In this review, we summarize the current knowledge on archaeal EVs ...

  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Germano Cecere; Meetali Singh; Eric Cornes; Blaise Li; Piergiuseppe Quarato; Loan Bourdon; Florent Dingli; Damarys Loew; Simone Procaccia;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | RNAEPIGEN (679243)

    22G-RNAs are single-stranded antisense small RNAs that are expressed in C. elegans germline. Here the authors show that CSR-1 dependent 22G-RNAs are produced in the cytosol on mRNAs actively engaged in translation and that codon usage of an mRNA regulates the biogenesis...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Batsché, Eric; Yi, Jia; Mauger, Oriane; Kornobis, Etienne; Hopkins, Benjamin; Hanmer-Lloyd, Charlotte; Muchardt, Christian;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | PASTEURDOC (665807)

    International audience; DNA methylation (meDNA) is a modulator of alternative splicing, and splicing perturbations are involved in tumorigenesis nearly as frequently as DNA mutations. However, the impact of meDNA on tumorigenesis via splicing-mediated mechanisms has not...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Chiva, Cristina; Mendes Maia, Teresa; Panse, Christian; Stejskal, Karel; Douché, Thibaut; Matondo, Mariette; Loew, Damarys; Helm, Dominic; Rettel, Mandy; Mechtler, Karl; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | EPIC-XS (823839)

    International audience; Proteomics research infrastructures and core facilities within the Core for Life alliance advocate for community policies for quality control to ensure high standards in proteomics services.

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  • publication . Article . 2021
    Open Access English
    Authors:
    Pende, Nika; Sogues, Adrià; Megrian, Daniela; Sartori-Rupp, Anna; England, Patrick; Palabikyan, Hayk; Rittmann, Simon K.-M. R.; Graña, Martín; Wehenkel, Anne Marie; Alzari, Pedro M.; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: EC | PASTEURDOC (665807)

    Most archaea divide by binary fission using an FtsZ-based system that is poorly understood. Here, the authors combine structural, cellular, and evolutionary analyses to show that the SepF protein acts as the FtsZ anchor in the archaeon Methanobrevibacter smithii.

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  • publication . Preprint . Other literature type . Article . 2021
    Open Access English
    Authors:
    Sébastien Herbert; Léo Valon; Laure Mancini; Nicolas Dray; Paolo Caldarelli; Jerome Gros; Elric Esposito; Spencer L. Shorte; Laure Bally-Cuif; Romain Levayer; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | SYSTEMATICS (322936), EC | PASTEURDOC (665807), EC | CoSpaDD (758457), EC | LIMBCELLDYNAMICS (337635)

    BackgroundQuantitative imaging of epithelial tissues prompts for bioimage analysis tools that are widely applicable and accurate. In the case of imaging 3D tissues, a common pre-processing step consists in projecting the acquired 3D volume on a 2D plane mapping the tiss...

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8,859 research outcomes, page 1 of 886