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164 research outcomes, page 1 of 17
  • publication . Preprint . Other literature type . 2021
    Open Access English
    Authors:
    Eleftherios Zarkadas; Hong Zhang; Wensheng Cai; Gregory Effantin; Jonathan Perot; Jacques Neyton; Christophe Chipot; Guy Schoehn; François Dehez; Hugues Nury;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | PentaBrain (637733)

    Inaccurately perceived as niche drugs, antiemetics are key elements of cancer treatment alleviating the most dreaded side effect of chemotherapy. Serotonin 5-HT3 receptor antagonists are the most commonly prescribed class of drugs to control chemotherapy-induced nausea ...

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  • publication . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Lynda Djerbal; Romain R. Vivès; Chrystel Lopin-Bon; Ralf P. Richter; Jessica C. F. Kwok; Hugues Lortat-Jacob;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    ABSTRACTSemaphorin 3A (Sema3A) is a secreted protein that signals to cells through binding to neuropilin and plexin receptors and provides neurons with guidance cues key for axon pathfinding, and also controls cell migration in several other biological systems. Sema3A i...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Marion Lechable; Alexandre Jan; Axel Duchene; Julie Uveira; Brandon Weissbourd; Loann Gissat; Sophie Collet; Laurent Gilletta; Sandra Chevalier; Lucas Leclère; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | CORBEL (654248), ANR | i-MMEJ (ANR-17-CE13-0016), EC | ASSEMBLE Plus (730984)

    ABSTRACT The jellyfish species Clytia hemisphaerica (Cnidaria, Hydrozoa) has emerged as a new experimental model animal in the last decade. Favorable characteristics include a fully transparent body suitable for microscopy, daily gamete production and a relatively short...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    K.K. Rasmussen; Andrés Palencia; Anders K. Varming; Habiba El-Wali; Elisabetta Boeri Erba; Martin Blackledge; Karin Hammer; Torsten Herrmann; Mogens Kilstrup; Leila Lo Leggio; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706), EC | ERCSC-CHAIRS-SUP2013 (341400), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Temperate bacteriophages can enter one of two life cycles following infection of a sensitive host: the lysogenic or the lytic life cycle. The choice between the two alternative life cycles is dependent upon a tight regulation of promoters and their cognate regulatory pr...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Tao Jiang; Amandine Roux; Sylvain Engilberge; Zaynab Alsalman; Sebastiano Di Pietro; Bruno Franzetti; François Riobé; Olivier Maury; Eric Girard;
    Publisher: HAL CCSD

    ABSTRACTIn this article, the principle of a database aimed at facilitating the understanding of the unique protein nucleating properties of the Crystallophore is presented. A first analysis allows us to compare the efficiency of Tb-Xo4 with the new Lu-Xo4 variant, featu...

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  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Aldo R. Camacho-Zarco; Sissy Kalayil; Damien Maurin; Nicola Salvi; Elise Delaforge; Sigrid Milles; Malene Ringkjøbing Jensen; Darren J. Hart; Stephen Cusack; Martin Blackledge;
    Publisher: Nature Publishing Group
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | AvINFLUENZA (796490)

    Avian influenza polymerase undergoes host adaptation in order to efficiently replicate in human cells. Here, the authors use NMR spectroscopy and quantitative ensemble modelling to describe the highly dynamic assemblies formed by the human-adapted or avian-adapted C-ter...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    carlos oscar Sorzano; Enrique Crisman; Jose Maria Carazo; rafael leon;
    Project: EC | CORBEL (654248), EC | INSTRUCT-ULTRA (731005), EC | HighResCells (810057), EC | IMpaCT (857203), EC | iNEXT-Discovery (871037), EC | EOSC-Life (824087), EC | EOSC-synergy (857647)

    No

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  • publication . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Daniel Scholl; Maud Sigoillot; Marie Overtus; Rafael Colomer Martinez; Chloe Martens; Yiting Wang; Els Pardon; Toon Laeremans; Abel Garcia-Pino; Jan Steyaert; ...
    Persistent Identifiers
    Project: EC | INSTRUCT-ULTRA (731005)

    AbstractCystic Fibrosis (CF) is a common lethal genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. Misfolding and degradation of CFTR are the hallmarks of the predominant mutation, F508del, located in th...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Flaugnatti, Nicolas; Rapisarda, Chiara; Rey, Martial; Beauvois, Solène,; Nguyen, Viet anh; Canaan, Stéphane; Durand, Eric; Chamot‐Rooke, Julia; Cascales, E.; Fronzes, Rémi; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706)

    International audience; The bacterial type VI secretion system (T6SS) is a macromolecular machine that injects effectors into prokaryotic and eukaryotic cells. The mode of action of the T6SS is similar to contractile phages: the contraction of a sheath structure pushes ...

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  • publication . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Clarisse Uwizeye; Johan Decelle; Pierre-Henri Jouneau; Benoit Gallet; Jean-Baptiste Keck; Christine Moriscot; Fabien Chevalier; Nicole L. Schieber; Rachel Templin; Gilles Curien; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | CBH-EUR-GS (ANR-17-EURE-0003), EC | CORBEL (654248), EC | ChloroMito (833184), ANR | MoMix (ANR-17-CE05-0029)

    AbstractPhytoplankton is a minor fraction of the global biomass playing a major role in primary production and climate. Despite improved understanding of phytoplankton diversity and genomics, we lack nanoscale subcellular imaging approaches to understand their physiolog...

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164 research outcomes, page 1 of 17