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256 research outcomes, page 1 of 26
  • publication . Article . Other literature type . Preprint . 2021
    Open Access English
    Authors:
    Maryam Alqabandi; N. de Franceschi; Nolwenn Miguet; Sourav Maity; Marta Bally; Wouter H. Roos; Winfried Weissenhorn; Patricia Bassereau; Stéphanie Mangenot;
    Project: ANR | PSL (ANR-10-IDEX-0001), EC | ESCRT model (751715), ANR | ESCRTfission (ANR-14-CE09-0003), EC | INTERACT (751404), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Abstract Background ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast. In humans, ESCRT-III CHMP2 exists as two isoforms, CHMP2A and CHMP2B, but their physical characteristics have...

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  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Sergi López-Serrano; Lorena Cordoba; Mónica Pérez-Maillo; Patricia Pleguezuelos; Edmond J. Remarque; Thomas Ebensen; Carlos A. Guzmán; Dennis Christensen; Joaquim Segalés; Ayub Darji;
    Persistent Identifiers
    Publisher: MDPI
    Project: EC | TRANSVAC2 (730964)

    This study aimed to evaluate the immune response and protection correlates against influenza virus (IV) infection in pigs vaccinated with the novel NG34 HA1 vaccine candidate adjuvanted with either CAF®01 or CDA/αGalCerMPEG (αGCM). Two groups of six pigs each were vacci...

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  • publication . Article . Other literature type . 2021
    Open Access English
    Authors:
    Begoña Alburquerque-González; Ángel Bernabé-García; Manuel Bernabé-García; Javier Ruiz-Sanz; Fernando Feliciano López-Calderón; Leonardo Gonnelli; Lucia Banci; Jorge Peña-García; Irene Luque; Francisco José Nicolás; ...
    Persistent Identifiers
    Publisher: MDPI AG
    Project: EC | CORBEL (654248)

    Fundación Seneca 20988/PI/18 20646/JLI/18

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Lucia Gigli; Enrico Ravera; Vito Calderone; Claudio Luchinat;
    Persistent Identifiers
    Publisher: MDPI AG

    Nature has evolved several molecular machineries to promote the formation at physiological conditions of inorganic materials, which would otherwise be formed in extreme conditions. The molecular determinants of this process have been established over the last decade, id...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Signe Tandrup Schmidt; Dennis Christensen; Yvonne Perrie;
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: EC | TRANSVAC2 (730964)

    Subunit vaccines require particulate adjuvants to induce the desired immune responses. Pre-clinical manufacturing methods of adjuvants are often batch dependent, which complicates scale-up for large-scale good manufacturing practice (GMP) production. The cationic liposo...

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  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Marion Lechable; Alexandre Jan; Axel Duchene; Julie Uveira; Brandon Weissbourd; Loann Gissat; Sophie Collet; Laurent Gilletta; Sandra Chevalier; Lucas Leclère; ...
    Persistent Identifiers
    Publisher: The Company of Biologists
    Project: EC | ASSEMBLE Plus (730984), ANR | i-MMEJ (ANR-17-CE13-0016), EC | CORBEL (654248)

    ABSTRACT The jellyfish species Clytia hemisphaerica (Cnidaria, Hydrozoa) has emerged as a new experimental model animal in the last decade. Favorable characteristics include a fully transparent body suitable for microscopy, daily gamete production and a relatively short...

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  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    K.K. Rasmussen; Andrés Palencia; Anders K. Varming; Habiba El-Wali; Elisabetta Boeri Erba; Martin Blackledge; Karin Hammer; Torsten Herrmann; Mogens Kilstrup; Leila Lo Leggio; ...
    Persistent Identifiers
    Publisher: Proceedings of the National Academy of Sciences
    Project: EC | ERCSC-CHAIRS-SUP2013 (341400), EC | iNEXT (653706), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Temperate bacteriophages can enter one of two life cycles following infection of a sensitive host: the lysogenic or the lytic life cycle. The choice between the two alternative life cycles is dependent upon a tight regulation of promoters and their cognate regulatory pr...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Herimela Solomon-Degefa; Jan M. Gebauer; Cy M. Jeffries; Carolin D. Freiburg; Patrick Meckelburg; Louise E. Bird; Ulrich Baumann; Dmitri I. Svergun; Raymond J. Owens; Jörn M. Werner; ...
    Publisher: Deutsches Elektronen-Synchrotron, DESY, Hamburg
    Project: EC | iNEXT (653706)

    Published by American Soc. for Biochemistry and Molecular Biology8772, Bethesda, MD.

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    David Střelák; Jiří Filipovič; Amaya Jiménez-Moreno; José María Carazo; Carlos Oscar S. Sorzano;
    Persistent Identifiers
    Project: EC | INPhINIT (713673), EC | INSTRUCT-ULTRA (731005), EC | EOSC-Life (824087), EC | HighResCells (810057), EC | CORBEL (654248)

    Cryogenic Electron Microscopy (Cryo-EM) has been established as one of the key players in Structural Biology. It can reconstruct a 3D model of the sample at the near-atomic resolution, which led to a Method of the year award by Nature, and the Nobel Prize in 2017. With ...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Nicolas Flaugnatti; Chiara Rapisarda; Martial Rey; Solène G Beauvois; Viet Anh Nguyen; Stéphane Canaan; Eric Durand; Julia Chamot-Rooke; Eric Cascales; Rémi Fronzes; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706)

    International audience; The bacterial type VI secretion system (T6SS) is a macromolecular machine that injects effectors into prokaryotic and eukaryotic cells. The mode of action of the T6SS is similar to contractile phages: the contraction of a sheath structure pushes ...

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256 research outcomes, page 1 of 26