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  • Open Access
    Authors: 
    Sarah Temmam; Khamsing Vongphayloth; Eduard Baquero; Sandie Munier; Massimiliano Bonomi; Béatrice Regnault; Bounsavane Douangboubpha; Yasaman Karami; Delphine Chrétien; Daosavanh Sanamxay; +16 more
    Publisher: Zenodo
    Country: France

    International audience; The animal reservoir of SARS-CoV-2 is unknown despite reports of SARS-CoV-2-related viruses in Asian Rhinolophus bats1-4, including the closest virus from R. affinis, RaTG13 (refs. 5,6), and pangolins7-9. SARS-CoV-2 has a mosaic genome, to which ...

  • Open Access English
    Authors: 
    Tamas Fulop; Anis Larbi; Graham Pawelec; Alan A. Cohen; Guillaume Provost; Abedelouahed Khalil; Guy Lacombe; Serafim Rodrigues; Mathieu Desroches; Katsuiku Hirokawa; +2 more
    Publisher: HAL CCSD
    Country: France

    International audience; Organismal ageing is associated with many physiological changes, including differences in the immune system of most animals. These differences are often considered to be a key cause of age-associated diseases as well as decreased vaccine response...

  • Open Access English
    Authors: 
    Ivan Lerner; Arnaud Serret-Larmande; Bastien Rance; Nicolas Garcelon; Anita Burgun; Laurent Chouchana; Antoine Neuraz;
    Publisher: HAL CCSD
    Country: France

    Background Patients hospitalized for a given condition may be receiving other treatments for other contemporary conditions or comorbidities. The use of such observational clinical data for pharmacological hypothesis generation is appealing in the context of an emerging...

  • Authors: 
    Fanticelli, Haron; Rabenjamina, Solohaja; Carneiro Viana, Aline; Stanica, Razvan; Santos De Oliveira, Lucas; Ziviani, Artur;
    Publisher: Association for Computing Machinery (ACM)
    Country: France

    The idea of using mobile phone data to understand the impact of the Covid-19 pandemic and that of the sanitary constraints associated with it on human mobility imposed itself as evidence in most countries. This work uses spatiotemporal aggregated mobile phone data prov...

  • English
    Authors: 
    Guillaume Cantin; Cristiana J. Silva; Arnaud Banos;
    Publisher: HAL CCSD
    Country: France

    <p style='text-indent:20px;'>In this paper, we investigate the well-posedness and dynamics of a class of hybrid models, obtained by coupling a system of ordinary differential equations and an agent-based model. These hybrid models intend to integrate the microscop...

  • Open Access English
    Authors: 
    Qi Luo; Ryan Weightman; Sean T. McQuade; Mateo Díaz; Emmanuel Trélat; William Barbour; Dan Work; Samitha Samaranayake; Benedetto Piccoli;
    Country: France

    <p style='text-indent:20px;'>During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioni...

  • Open Access English
    Authors: 
    Erika Cecon; Julie Dam; Ralf Jockers;
    Publisher: HAL CCSD
    Country: France

    The SARS-CoV-2 coronavirus infects human cells through the interaction of the viral envelope Spike protein (IPR044366) with the human Angiotensin-Converting Enzyme 2 (ACE2), expressed at the surface of target cells. Here, we describe a detailed protocol to measure the b...

  • Open Access English
    Authors: 
    Mehdi Stiti; Guillaume Castanet; Andrew Corber; Marcus Aldén; Edouard Berrocal;
    Publisher: HAL CCSD
    Country: France
    Project: EC | Spray-Imaging (638546)

    To control the evolution of a pandemic such as COVID-19, knowing the conditions under which the pathogen is being transmitted represents a critical issue, especially when implementing protection strategies like social distancing and face masks wearing. For viruses and b...

  • Closed Access
    Authors: 
    Kaat Philippe; Sylvie Issanchou; Sandrine Monnery-Patris;
    Publisher: Elsevier BV
    Country: France

    International audience; Using open-ended questions, this study explored parents’ experiences regarding changes in their family’s food-related behaviours during the first COVID-19 lockdown in France (March- May 2020). Parents (N=498, 72% mothers) of children aged 3-12 ye...

  • Open Access English
    Authors: 
    Thomas Meunier; Lowiese Desmarets; Simon Bordage; Moussa Bamba; Kévin Hervouet; Yves Rouillé; Nathan François; Marion Decossas; Valentin Sencio; François Trottein; +6 more
    Publisher: HAL CCSD
    Country: France

    International audience; The SARS-CoV-2 outbreak has highlighted the need for broad-spectrum antivirals against coronaviruses (CoVs). Here, pheophorbide a (Pba) was identified as a highly active antiviral molecule against HCoV-229E after bioguided fractionation of plant ...