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295 research outcomes, page 1 of 30
  • publication . Conference object . Preprint . 2021
    Open Access English
    Authors:
    Muhammad Umar B Niazi; Alain Kibangou; Carlos Canudas de Wit; Denis Nikitin; Liudmila Tumash; Pierre-Alexandre Bliman;
    Publisher: HAL CCSD
    Country: France
    Project: EC | Scale-FreeBack (694209)

    Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment or vaccine is available. In thi...

  • publication . Article . 2021
    Open Access English
    Authors:
    Samuele Bovo; Giuseppina Schiavo; Anisa Ribani; Valerio Joe Utzeri; Valeria Taurisano; Mohamad Ballan; María Muñoz; Estefania Alves; José Pedro Araújo; Riccardo Bozzi; ...
    Persistent Identifiers
    Publisher: Nature Research
    Countries: France, Italy, Serbia, Spain, Croatia, Italy
    Project: EC | TREASURE (634476)

    AbstractCoronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that c...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Benjamin Gaborit; Bernard Vanhove; Marie-Anne Vibet; Aurélie Le Thuaut; Karine Lacombe; Vincent Dubee; Florence Ader; Virginie Ferre; Eric Vicaut; Jéremie Orain; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | BRIGHT (962036)

    Abstract Background Early inhibition of entry and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a very promising therapeutic approach. Polyclonal neutralizing antibodies offers many advantages such as providing immediate immunity, co...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Romain Marlin; Véronique Godot; Sylvain Cardinaud; Mathilde Galhaut; Severin Coleon; Sandra Zurawski; Nathalie Dereuddre-Bosquet; Mariangela Cavarelli; Anne-Sophie Gallouet; Pauline Maisonnasse; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVAg (653316), ANR | IDMIT (ANR-11-INBS-0008), EC | TRANSVAC2 (730964)

    Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require additional approaches to currently approved viral vector and mRNA vaccines. Subunit vaccines may have distinct advantages when immunizing vulnerable individuals, children and pregnant wo...

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini; Pierre-Yves Boëlle; Vittoria Colizza;
    Publisher: Nature Publishing Group UK
    Country: France
    Project: ANR | DataRedux (ANR-19-CE46-0008), EC | MOOD (874850), ANR | SPHINx (ANR-17-CE36-0008)

    As countries in Europe implement strategies to control the COVID-19 pandemic, different options are chosen regarding schools. Through a stochastic age-structured transmission model calibrated to the observed epidemic in Île-de-France in the first wave, we explored scena...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Natacha S. Ogando; Priscila El Kazzi; Jessika C. Zevenhoven-Dobbe; Brenda w. Bontes; Alice Decombe; Clara C. Posthuma; Volker Thiel; Bruno Canard; François Ferron; Etienne Decroly; ...
    Publisher: National Academy of Sciences NAS
    Countries: Switzerland, France
    Project: EC | ANTIVIRALS (642434)

    As coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their messenger RNAs (mRNAs), protect them from degradation by cellular 5′ exoribonucleases (ExoNs), and escape innate immune se...

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  • publication . Article . Conference object . 2021
    Open Access English
    Authors:
    Estcourt, L.J.; Turgeon, A.F.; McQuilten, Z.K.; McVerry, B.J.; Al-Beidh, F.; Annane, D.; Arabi, Y.M.; Arnold, D.M.; Beane, A.; Bégin, P.; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: Netherlands, France, Netherlands, France, France, Netherlands, United Kingdom
    Project: EC | PREPARE (602525)

    International audience; Importance: The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive. Objective: To determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19. Design, Set...

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  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Bernard Vanhove; Stéphane Marot; Ray T. So; Benjamin Gaborit; Benjamin Gaborit; Gwénaëlle Evanno; Isabelle Malet; Guillaume Lafrogne; Edwige Mevel; Carine Ciron; ...
    Publisher: HAL CCSD
    Country: France
    Project: EC | BRIGHT (962036)

    AbstractAmino acid substitutions and deletions in Spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants can reduce the effectiveness of monoclonal antibodies (mAbs). In contrast, heterologous polyclonal antibodies raised against S pr...

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  • publication . Article . Preprint . 2021
    Open Access
    Authors:
    Peter Czuppon; Emmanuel Schertzer; François Blanquart; Florence Débarre;
    Publisher: The Royal Society
    Country: France
    Project: EC | PolyPath (844369), ANR | TheoGeneDrive (ANR-19-CE45-0009)

    Emerging epidemics and local infection clusters are initially prone to stochastic effects that can substantially impact the epidemic trajectory. While numerous studies are devoted to the deterministic regime of an established epidemic, mathematical descriptions of the i...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Nathalie Bajos; François Beck; Nathalie Lydié; Claude Martin; Florence Jusot; Laurence Meyer; Rémy Slama; Josiane Warszawski; Jeanna-eve Franck; Emilie Counil; ...
    Persistent Identifiers
    Country: France
    Project: EC | GENDHI (856478)

    ObjectiveAlthough social inequalities in COVID-19 mortality by race, gender and socioeconomic status are well documented, less is known about social disparities in infection rates and their shift over time. We aim to study the evolution of social disparities in infectio...

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295 research outcomes, page 1 of 30