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416 research outcomes, page 1 of 42
  • publication . Conference object . Preprint . 2021
    Open Access English
    Authors:
    Muhammad Umar B Niazi; Alain Kibangou; Carlos Canudas de Wit; Denis Nikitin; Liudmila Tumash; Pierre-Alexandre Bliman;
    Publisher: HAL CCSD
    Country: France
    Project: EC | Scale-FreeBack (694209)

    Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment or vaccine is available. In thi...

  • publication . Article . 2021
    Open Access English
    Authors:
    Tingting Li; Hongmin Cai; Yapei Zhao; Yanfang Li; Yanling Lai; Hebang Yao; Liu Daisy Liu; Zhou Sun; Martje Fentener van Vlissingen; Thijs Kuiken; ...
    Persistent Identifiers
    Publisher: John Wiley and Sons Inc.
    Project: EC | ERINHA-Advance (824061)

    Abstract An essential step for SARS‐CoV‐2 infection is the attachment to the host cell receptor by its Spike receptor‐binding domain (RBD). Most of the existing RBD‐targeting neutralizing antibodies block the receptor‐binding motif (RBM), a mutable region with the poten...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Wasfi Fares; Kais Ghedira; Mariem Gdoura; Anissa Chouikha; Sondes Haddad-Boubaker; Marwa Khedhiri; Kaouthar Ayouni; Asma Lamari; Henda Touzi; Walid Hammemi; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | STAMINA (883441)

    ABSTRACT Recent efforts have reported numerous variants that influence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral characteristics, including pathogenicity, transmission rate, and detectability by molecular tests. Whole-genome sequencing based on ...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Samuele Bovo; Giuseppina Schiavo; Anisa Ribani; Valerio Joe Utzeri; Valeria Taurisano; Mohamad Ballan; María Muñoz; Estefania Alves; José Pedro Araújo; Riccardo Bozzi; ...
    Persistent Identifiers
    Publisher: Nature Research
    Countries: France, Italy, Serbia, Spain, Croatia, Italy
    Project: EC | TREASURE (634476)

    AbstractCoronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that c...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Benjamin Gaborit; Bernard Vanhove; Marie-Anne Vibet; Aurélie Le Thuaut; Karine Lacombe; Vincent Dubee; Florence Ader; Virginie Ferre; Eric Vicaut; Jéremie Orain; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | BRIGHT (962036)

    Abstract Background Early inhibition of entry and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a very promising therapeutic approach. Polyclonal neutralizing antibodies offers many advantages such as providing immediate immunity, co...

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  • publication . Article . 2021
    Open Access
    Authors:
    Laura Di Domenico; Chiara E. Sabbatini; Pierre-Yves Boëlle; Chiara Poletto; Pascal Crépey; Juliette Paireau; Simon Cauchemez; François Beck; Harold Noel; Daniel Lévy-Bruhl; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: EC | MOOD (874850), ANR | EVALCOVID-19 (ANR-20-COVI-0007)

    Abstract Background After one year of stop-and-go COVID-19 mitigation, in the spring of 2021 European countries still experienced sustained viral circulation due to the Alpha variant. As the prospect of entering a new pandemic phase through vaccination was drawing close...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Andrii Rabets; Galyna Bila; Roman Grytsko; Markian Samborskyy; Yuriy Rebets; Sandor G. Vari; Quentin Pagneux; Alexandre Barras; Rabah Boukherroub; Sabine Szunerits; ...
    Persistent Identifiers
    Publisher: Springer Verlag
    Country: France
    Project: EC | NoBiasFluors (872331), EC | NeutroCure (861878)

    Coronaviruses share conservative spike protein (S) on their enveloped membrane surface, where S1 subunit recognizes and binds the cellular receptor, and the S2 subunit mediates membrane fusion. This similarity raises the question: does coronaviral infection by one creat...

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  • publication . Article . 2021
    Open Access English
    Authors:
    Romain Marlin; Véronique Godot; Sylvain Cardinaud; Mathilde Galhaut; Severin Coleon; Sandra Zurawski; Nathalie Dereuddre-Bosquet; Mariangela Cavarelli; Anne-Sophie Gallouet; Pauline Maisonnasse; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France
    Project: EC | EVAg (653316), ANR | IDMIT (ANR-11-INBS-0008), EC | TRANSVAC2 (730964)

    Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require additional approaches to currently approved viral vector and mRNA vaccines. Subunit vaccines may have distinct advantages when immunizing vulnerable individuals, children and pregnant wo...

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  • publication . Preprint . Article . 2021
    Open Access English
    Authors:
    Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini; Pierre-Yves Boëlle; Vittoria Colizza;
    Publisher: Nature Publishing Group UK
    Country: France
    Project: ANR | DataRedux (ANR-19-CE46-0008), EC | MOOD (874850), ANR | SPHINx (ANR-17-CE36-0008)

    As countries in Europe implement strategies to control the COVID-19 pandemic, different options are chosen regarding schools. Through a stochastic age-structured transmission model calibrated to the observed epidemic in Île-de-France in the first wave, we explored scena...

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  • publication . Article . 2021
    Open Access English
    Authors:
    João Pedro Ferreira; Nicolas Girerd; Hans-Peter Brunner-La Rocca; Pierpaolo Pellicori; John G.F. Cleland; Patrick Rossignol; Faiez Zannad;
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: France, France, Netherlands
    Project: EC | HOMAGE (305507)

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