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Background: Senegal reported the first COVID-19 case on March 2, 2020. A nationwide cross-sectional epidemiological survey was conducted to capture the true extent of COVID-19 exposure. Methods: Multi-stage random cluster sampling of households was carried out between October 24 and November 26, 2020, at the end of the first wave of COVID-19 transmission. Anti-SARS-CoV-2 antibodies (IgG and/or IgM) were screened using three distinct ELISA assays. Adjusted prevalence for the survey design were calculated for each test separately, and thereafter combined. Crude, adjusted prevalence based on tests performances and weighted prevalence by sex-age strata were estimated to assess the seroprevalence. Findings: Of the 1,463 participants included in this study, 58·8% were women and the mean age of participants was 29·2 years (range 0·25–82·0). The national seroprevalence was estimated at 28 . 4% (95% CI: 26·1-30·8). There was substantial regional variability. Four regions recorded the highest seroprevalence: Ziguinchor (56·7%), Sedhiou (48·0%), Dakar (44·0%) and Kaolack (32·7%) whereas, Louga (11·1%) and Matam (11·2%), located in the Center-North, were less impacted in our analysis. All age groups were impacted and the prevalence of SARS-CoV-2 was comparable in symptomatic and asymptomatic groups. We estimated 4,744,392 SARS-CoV-2 (95% CI: 4,360,164 – 5,145,327) potential infected in Senegal compared to 16,089 COVID-19 RT-PCR laboratory-confirmed cases reported at the time of the survey. Interpretation: These results provide an estimate of SARS-CoV-2 virus dissemination in the Senegalese population. Preventive and control measures need to be reinforced in the country and especially in the south border regions. Funding Information: This work was supported by US Centers for Disease Control and Prevention (CDC), the Senegalese Ministry of Health, the Senegalese National Statistics and Demography Agency (ANSD), the WHO Unity program and the COVID-19 Task-force of the International Pasteur Institute Network (IPIN, REPAIR project). Declaration of Interests: We declare no competing interests. Ethics Approval Statement: All participants have consented to participate in the study. For people younger than 18 years, a legal representative provided informed consent. The study was approved by the Senegalese National Ethics Committee for Research in Health (reference number N°0176/MSAS/DPRS/CNERS, 10 October 2020).

COVID-19 outbreaks at nursing homes during the recent pandemic, which received ample media coverage, may have lasting negative impacts on individuals’ perceptions regarding ursing homes. We argue that this could have sizable and persistent implications for savings and long-term care policies. We first develop a theoretical model predicting that higher nurs- ing home aversion should induce higher savings and stronger support for policies subsidizing home care. We further document, based on a survey on Canadians in their 50s and 60s, that higher nursing home aversion is widespread: 72% of respondents are less inclined to enter a nursing home because of the pandemic. Consistent with our model, we find that the latter are much more likely to have higher intended savings for older age because of the pandemic. We also find that they are more likely to strongly support home care subsidies.

Italy was hit harshly by the Covid-19 pandemic, registering more than 35,000 Covid-19 deaths between February and July 2020. During this first wave of the epidemic, the virus spread unequally across the country, with northern regions witnessing more cases and deaths. We investigate demographic and socio-economic factors contributing to the diverse regional impact of the virus during the first wave. Using generalized additive mixed models, we find that Covid-19 mortality at regional level is negatively associated with the degree of intergenerational co-residence, number of intensive care unit beds per capita, and delay in the outbreak of the epidemic. Conversely, we do not find strong associations for several variables highlighted in recent literature, such as population density or the share of the population who are older or have at least one chronic disease. Our results underscore the importance of context-specific analysis for the study of a pandemic.

This paper examines the empirical relationship between individuals’ cognitive and non-cognitive abilities and COVID-19 compliance behaviors using cross-country data from the Survey of Health, Ageing and Retirement in Europe (SHARE). We find that both cognitive and non-cognitive skills predict responsible health behaviors during the COVID-19 crisis. Episodic memory is the most important cognitive skill, while conscientiousness and neuroticism are the most significant personality traits. There is also some evidence of a role for an internal locus of control in compliance. usc Refereed/Peer-reviewed

Abstract Fast, sensitive, high-throughput detection of coronavirus antigens at physiologically relevant levels is essential for population screening that could prevent epidemics such as the current COVID-19 global pandemic. Optical methods based on surface-enhanced Raman scattering (SERS) spectroscopy are promising for this purpose because they ensure quick detection of even single biological molecules in a sample. For achieving such a high sensitivity, it is crucial to design SERS-active systems concentrating incident radiation into small sample volumes. Here, metal-dielectric cavities have been obtained through interaction of protein sulfhydryl groups with a SERS-active silver surface. The concentration of light in these cavities allows the differential detection of spike glycoprotein and nucleocapsid protein of SARS-COV-2, which are its key antigens, at physiologically relevant concentrations. The cavity Q-factor can be increased by additionally covering the dielectric protein film with a silver shell to form an ultrathin cavity, which provides an at least tenfold enhancement of the detection signal. The results could be used to design high-throughput systems for specific and sensitive detection of viral antigens and quick diagnosis of viral infections.

International audience; Today, health care is at a high level of dynamism. To survive in such conditions, performance assessment can play an effective role in providing quality health care. To develop and compete, health system units need a productivity assessment system to measure their programs and processes' efficiency and effectiveness.The purpose of this study is to measure the productivity changes of health system units using the Malmquist index. Productivity assessment of health system units provides the necessary information for managers to monitor these centers' current situation and activities. The present study's statistical population includes 28 units of the world health system with a minimum of 42 days of exposure to COVID-19. In this study, the performance of health system units has been measured based on 4 indicesthat include "Day of Infection, Total Cases" as inputs and "Total Deaths, Total Recovered" as outputsthat are from the "Worldometer" database.The present descriptive study was conducted in three 14-day COVID-19 incubation periods after the countries were exposed. The results showed that the mean of the productivity changes of the health system units did not have a steady growth trend so that the average changes of the total productivity of the health system units from the first to second incubation period was 0.92 and from the second to third incubation period was 1.58, which is an indication of the unstable growth in the productivity of the studied health system units.

Abstract The global lockdowns brought on by the COVID-19 pandemic forced an immediate change in the way people moved about;namely, travel was slowed from a turbulent river to a trickle In-person meetings, often involving long-distance flights, were either canceled, postponed, or shifted over to virtual modes People who were unfamiliar with online meetings quickly became acquainted with them

International audience; In honour of the International Year of Sound and for the 1 year memorial of the Notre-Dame cathedral fire, a team of researchers and sound engineers created a virtual reconstruction of a concert in the cathedral, using close-mic recordings made on 24-April-2013 of a performance of La Vierge by Jules Massenet. This reconstruction was carried out during the period of strict COVID-19 confinement. With 83 musicians, 6 singers and a 160person choir spatially distributed throughout the cathedral, the original performance offered a spatial composition highlighting the complex acoustics and interactions between source and listener positions. Individual tracks were convolved with spatial room impulse responses, created from a calibrated geometrical acoustic simulation. Several listening positions were binaurally rendered, along with an artistic mix created by a sound engineer, offering a unique 3d-audio experience approaching the reality of the moment in the past. Distributed on-line, the website presenting this virtual reconstruction has been visited from users around the world. A listener opinion survey was included on the website. This paper presents an overview of the source material, the production workflow, and the challenges of realising such a production during confinement. Finally, an overview of visitor statistics and survey results is presented, providing insight into the reception of the virtual recreation and the interest towards future productions.

International audience; Background: In the absence of a treatment still considered universally effective, and of a vaccine validated by the health authorities, we wanted to know which Catholic saint the European Christian community turned to in the event of infection with Covid-19 to request a miraculous healing. Methodology: An online survey was carried out on a sample of 1158 adults using social media tools. Results: All results are presented in this research, with a few saints in the majority, and some dictated by the symptomatology of the Covid-19 infection or the personalities of certain « doctor guru ». Conclusion: This medico-anthropological study is revealing the psychology of Western patients vis-à-vis the magic-religious means used in the fight against diseases, particularly in the epidemic/pandemic context.

Pandemic disease is not merely a biological reality but also a cognitive and socially constructed phenomenon which intensely mobilizes a multiplicity of political frames. Far-right political entrepreneurs are, despite their remoteness from actual decision-making processes, active stakeholders in the current crisis. Existential threats to societies breed a sense of urgency and heightened cultural warfare that is a hotbed for extremism. Our study seeks to map, compare and contrast the symbolic responses to the Coronavirus crisis articulated by various far-right actors in two established democracies in the transatlantic area: The United States and France. We aim to shed light on how entrenched far-right mythologies and tropes—which appear increasingly transatlantic—are channeled into a new synthesis as part of an “alternative” political epistemology. Infused with the mythos of resistance and insurgency, resolutely anti-systemic, this alternative epistemology can better be described, following Michael Barkun, as a form of “stigmatized knowledge”. Our study will employ a Critical Discourse Analysis framework to bring into focus, in the response of the Euro-American far-right to the COVID-19 crisis, the ideological semiotics of the current “infodemic”.