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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Mammadova, Mahizar;

    Bu çalışmada tocilizumabisimli interlökin -6 blokeri kullanımının, Covid (SARS-CoV-2)hastalarında çok sık görülen sitokin fırtınası ve buna bağlı gelişen makrofaj aktivasyon sendromu (MAS) ile oluşan pnömoni üzerindeki etkileri araştırılmıştır. Yapılan çalışmada 100 kişilik hastaretrospektif olarak incelenmiş olup, hastalardan 50 tanesindetocilizumab kullanılmış ve tedavi süreci izlenmiştir. Diğer 50 hastada ise tocilizumab kullanımı olmaksızın tedavi süreci izlenmiştir. Çalışmamızda hastaların takip ve tedavi süreci dosyaüzerinden retrospektif olarak değerlendirilmiştir. Çalışmamız kapsamında, hastaların ferritin, CRP ( c reaktif protein) ve LDH (laktat dehidrogenaz) dahil inflamasyon belirteçleri tüm hastalarda değerlendirilmiştir. Çalışmaya konu olan tocilizumab kullanımının, covid geçiren hastaların ortalama ferritin (1432,30 ± 1307,96 ng/mL)ve ortalama CRP değeri (13.01 ± 7.79 mg/dL) üzerinde etkili olduğu, bu değerleri referans aralığına getirdiği görülmüştür. In this study, the effects of tocilizumab use on Sitokin storm and Pneumonia during the Covid period were investigated. In the study, 100 patients were examined and 50 of them were treated by using tocilizumab and the treatment process was followed. In the other 50 patients, the treatment process was followed without the use of tocilizumab. The study was conducted in a retrospectıve manner. Within the scope of the study, inflammation markers including ferritin, CRP and LDH were monitored in almost all patients. The use of tocilizumab, which was the subject of the study, was found to be effective on mean ferritin (1432.30 ± 1307.96 ng/mL) and mean CRP value (13.01 ± 7.79 mg/dL), and mainly regulated these values.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Başar, Özbür;

    Virtualization can be defined as software-based solutions of architectures that provide logical allocation of physical hardware resources. This can be done at different layers and for different purposes (servers, desktops, applications, storage and networking). Desktop virtualization, on the other hand, is a software system that enables people to access desktop resources anytime, anywhere via an internet connection and perform the work and transactions they need as if they were in front of a physical computer. According to the Gartner group, the main business drivers for adopting desktop virtualization are: application compatibility, business continuity, security and compliance, mobility, and enhanced productivity. Users can access desktop resources from any device, such as a computer, tablet, mobile phone, with a local or remote network connection to the central desktop virtualization server. In this study, architectures of Citrix XenDesktop, VMware Workstation, Microsoft Desktop virtualization systems with the same logical hardware are mentioned and two main virtualization architectures are focused. Session-based desktop virtualization (SBDV) and virtual desktop infrastructure (VDI). We will be comparing two host-based desktop virtualizations (VDI and SBDV) on these infrastructures, showing the difficulties faced by large organizations in creating a cost-effective and manageable desktop environment, and some advantages and disadvantages in different architectures. Finally, we will be sharing the benefits of desktop virtualization technologies during the pandemic period. Sanallaştırma, fiziksel donanım kaynaklarının mantıksal olarak paylaştırılmasını sağlayan mimarilerin yazılım temelli çözümleri olarak tanımlanabilir. Bu farklı katmanlarda ve farklı amaçlarla (sunucular, masaüstleri, uygulamalar, depolama ve ağ) gerçekleştirilebilir. Masaüstü sanallaştırma ise, insanların her an, her yerde, internet bağlantısı üzerinden masaüstü kaynaklarına erişerek ihtiyaç duyduğu iş ve işlemlerini, fiziksel bir bilgisayar karşısındaymış gibi yapabilmesini sağlayan yazılımsal sistemlerdir. Gartner grubuna göre, masaüstü sanallaştırmayı benimsemenin ana iş faktörleri şunlardır: uygulama uyumluluğu, iş sürekliliği, güvenlik ve uyumluluk, mobilite ve gelişmiş üretkenlik. Kullanıcılar, merkezi masaüstü sanallaştırma sunucusuna yerel veya uzak ağ bağlantısı olan bilgisayar, tablet, cep telefonu gibi herhangi bir cihazdan masaüstü kaynaklarına erişebilirler. Bu çalışmada, aynı mantıksal donanımlara sahip, Citrix XenDesktop, VMware Workstation, Microsoft Masaüstü sanallaştırma sistemlerinin mimarilerinden bahesilmiş ve iki ana sanallaştırma mimarisine odaklanılmıştır. Oturum tabanlı masaüstü sanallaştırma (SBDV) ve sanal masaüstü altyapısı (VDI). Bu altyapılarda büyük kuruluşların uygun maliyetli ve yönetilebilir bir masaüstü bilgisayar ortamı oluşturmadaki yaşanılan zorluklar ve farklı mimarilerdeki bazı avantaj ve dezavantajları gösteren iki ana sunucu tabanlı masaüstü sanallaştırmasını (VDI ve SBDV) karşılaştırıyor olacağız. Son olarak pandemi döneminde masaüstü sanallaştırma teknolojilerin sunduğu faydalarını paylaşılıyor olacağız.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Mammadova, Mahizar;

    Bu çalışmada tocilizumabisimli interlökin -6 blokeri kullanımının, Covid (SARS-CoV-2)hastalarında çok sık görülen sitokin fırtınası ve buna bağlı gelişen makrofaj aktivasyon sendromu (MAS) ile oluşan pnömoni üzerindeki etkileri araştırılmıştır. Yapılan çalışmada 100 kişilik hastaretrospektif olarak incelenmiş olup, hastalardan 50 tanesindetocilizumab kullanılmış ve tedavi süreci izlenmiştir. Diğer 50 hastada ise tocilizumab kullanımı olmaksızın tedavi süreci izlenmiştir. Çalışmamızda hastaların takip ve tedavi süreci dosyaüzerinden retrospektif olarak değerlendirilmiştir. Çalışmamız kapsamında, hastaların ferritin, CRP ( c reaktif protein) ve LDH (laktat dehidrogenaz) dahil inflamasyon belirteçleri tüm hastalarda değerlendirilmiştir. Çalışmaya konu olan tocilizumab kullanımının, covid geçiren hastaların ortalama ferritin (1432,30 ± 1307,96 ng/mL)ve ortalama CRP değeri (13.01 ± 7.79 mg/dL) üzerinde etkili olduğu, bu değerleri referans aralığına getirdiği görülmüştür. In this study, the effects of tocilizumab use on Sitokin storm and Pneumonia during the Covid period were investigated. In the study, 100 patients were examined and 50 of them were treated by using tocilizumab and the treatment process was followed. In the other 50 patients, the treatment process was followed without the use of tocilizumab. The study was conducted in a retrospectıve manner. Within the scope of the study, inflammation markers including ferritin, CRP and LDH were monitored in almost all patients. The use of tocilizumab, which was the subject of the study, was found to be effective on mean ferritin (1432.30 ± 1307.96 ng/mL) and mean CRP value (13.01 ± 7.79 mg/dL), and mainly regulated these values.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Başar, Özbür;

    Virtualization can be defined as software-based solutions of architectures that provide logical allocation of physical hardware resources. This can be done at different layers and for different purposes (servers, desktops, applications, storage and networking). Desktop virtualization, on the other hand, is a software system that enables people to access desktop resources anytime, anywhere via an internet connection and perform the work and transactions they need as if they were in front of a physical computer. According to the Gartner group, the main business drivers for adopting desktop virtualization are: application compatibility, business continuity, security and compliance, mobility, and enhanced productivity. Users can access desktop resources from any device, such as a computer, tablet, mobile phone, with a local or remote network connection to the central desktop virtualization server. In this study, architectures of Citrix XenDesktop, VMware Workstation, Microsoft Desktop virtualization systems with the same logical hardware are mentioned and two main virtualization architectures are focused. Session-based desktop virtualization (SBDV) and virtual desktop infrastructure (VDI). We will be comparing two host-based desktop virtualizations (VDI and SBDV) on these infrastructures, showing the difficulties faced by large organizations in creating a cost-effective and manageable desktop environment, and some advantages and disadvantages in different architectures. Finally, we will be sharing the benefits of desktop virtualization technologies during the pandemic period. Sanallaştırma, fiziksel donanım kaynaklarının mantıksal olarak paylaştırılmasını sağlayan mimarilerin yazılım temelli çözümleri olarak tanımlanabilir. Bu farklı katmanlarda ve farklı amaçlarla (sunucular, masaüstleri, uygulamalar, depolama ve ağ) gerçekleştirilebilir. Masaüstü sanallaştırma ise, insanların her an, her yerde, internet bağlantısı üzerinden masaüstü kaynaklarına erişerek ihtiyaç duyduğu iş ve işlemlerini, fiziksel bir bilgisayar karşısındaymış gibi yapabilmesini sağlayan yazılımsal sistemlerdir. Gartner grubuna göre, masaüstü sanallaştırmayı benimsemenin ana iş faktörleri şunlardır: uygulama uyumluluğu, iş sürekliliği, güvenlik ve uyumluluk, mobilite ve gelişmiş üretkenlik. Kullanıcılar, merkezi masaüstü sanallaştırma sunucusuna yerel veya uzak ağ bağlantısı olan bilgisayar, tablet, cep telefonu gibi herhangi bir cihazdan masaüstü kaynaklarına erişebilirler. Bu çalışmada, aynı mantıksal donanımlara sahip, Citrix XenDesktop, VMware Workstation, Microsoft Masaüstü sanallaştırma sistemlerinin mimarilerinden bahesilmiş ve iki ana sanallaştırma mimarisine odaklanılmıştır. Oturum tabanlı masaüstü sanallaştırma (SBDV) ve sanal masaüstü altyapısı (VDI). Bu altyapılarda büyük kuruluşların uygun maliyetli ve yönetilebilir bir masaüstü bilgisayar ortamı oluşturmadaki yaşanılan zorluklar ve farklı mimarilerdeki bazı avantaj ve dezavantajları gösteren iki ana sunucu tabanlı masaüstü sanallaştırmasını (VDI ve SBDV) karşılaştırıyor olacağız. Son olarak pandemi döneminde masaüstü sanallaştırma teknolojilerin sunduğu faydalarını paylaşılıyor olacağız.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Maltepe University I...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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