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3 research outcomes, page 1 of 1
  • publication . Article . 2018
    Open Access English
    Authors:
    Gómez-Sánchez, Rubén; Rose, Jaqueline; Guimarães, Rodrigo; Mari, Muriel; Papinski, Daniel; Rieter, Ester; Geerts, Willie J; Hardenberg, Ralph; Kraft, Claudine; Ungermann, Christian; ...
    Country: Netherlands
    Project: SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), FWF | Architecture and function... (P 25522), EC | PRONKJEWAIL (713660), NWO | The role of autophagy in ... (2300175628), FWF | Mechanisms and hierarchy ... (P 28113), EC | AutophagosomeSealing (655027), NWO | A three-dimensional look ... (2300175771)

    The autophagy-related (Atg) proteins play a key role in the formation of autophagosomes, the hallmark of autophagy. The function of the cluster composed by Atg2, Atg18, and transmembrane Atg9 is completely unknown despite their importance in autophagy. In this study, we...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Eisenberg-Bord, Michal; Mari, Muriel; Weill, Uri; Rosenfeld-Gur, Eden; Moldavski, Ofer; Castro, Inês G.; Soni, Krishnakant G.; Harpaz, Nofar; Levine, Tim P.; Futerman, Anthony H.; ...
    Country: Netherlands
    Project: UKRI | Delivering accurate struc... (BB/M011801/1), EC | MITOCHONTACTS (705853), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NIH | Phospholipids in Golgi Se... (5R01GM044530-16), NWO | A three-dimensional look ... (2300175771)

    Functional heterogeneity within the lipid droplet (LD) pool of a single cell has been observed, yet the underlying mechanisms remain enigmatic. Here, we report on identification of a specialized LD subpopulation characterized by a unique proteome and a defined geographi...

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  • other research product . Other ORP type . 2017
    Open Access English
    Authors:
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...

3 research outcomes, page 1 of 1