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5 Research products, page 1 of 1

  • Publications
  • Other research products
  • 2017-2021
  • Swiss National Science Foundation
  • A three-dimensional look into autophagy
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  • English
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  • Publication . Article . 2018
    Open Access English
    Authors: 
    Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian;

    doi: 10.1083/jcb.201804039

    handle: 11370/627ea07b-e6b9-4fe5-bd6a-bdcbbf353bb8

    pmc: PMC6168247

    pmid: 30097515

    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | The role of autophagy in ... (2300175628), NWO | A three-dimensional look ... (2300175771)

    Autophagy is a catabolic pathway that delivers intracellular material to the mammalian lysosomes or the yeast and plant vacuoles. The final step in this process is the fusion of autophagosomes with vacuoles, which requires SNARE proteins, the homotypic vacuole fusion an...

    addAdd to  ORCID orcid 
  • Publication . Article . 2018
    Open Access English
    Authors: 
    Gómez-Sánchez, Rubén; Rose, Jaqueline; Guimarães, Rodrigo; Mari, Muriel; Papinski, Daniel; Rieter, Ester; Geerts, Willie J; Hardenberg, Ralph; Kraft, Claudine; Ungermann, Christian; +3 more

    doi: 10.1083/jcb.201710116

    handle: 1874/372860 , 11370/8f45870f-f497-41d6-a36f-23ee7ff14f51

    pmc: PMC6080931

    pmid: 29848619

    Country: Netherlands
    Project: NWO | The role of autophagy in ... (2300175628), NWO | A three-dimensional look ... (2300175771), EC | AutophagosomeSealing (655027), FWF | Mechanisms and hierarchy ... (P 28113), FWF | Architecture and function... (P 25522), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    The autophagy-related (Atg) proteins play a key role in the formation of autophagosomes, the hallmark of autophagy. The function of the cluster composed by Atg2, Atg18, and transmembrane Atg9 is completely unknown despite their importance in autophagy. In this study, we...

    addAdd to  ORCID orcid 
  • Publication . Article . 2018
    Open Access English
    Authors: 
    Gao, Jieqiong; Langemeyer, Lars; Kümmel, Daniel; Reggiori, Fulvio; Ungermann, Christian;

    doi: 10.7554/elife.31145

    handle: 11370/fce735d9-c463-4077-acc4-518f24db81fe

    pmc: PMC5841931

    pmid: 29446751

    Country: Netherlands
    Project: NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), EC | DRIVE (765912)

    eLife digest Autophagy is a word derived from the Greek for “self-eating”. It describes a biological process in which a living cell breaks down its own material to release their chemical building blocks that can then be used to make new molecules. Autophagy is often tri...

    addAdd to  ORCID orcid 
  • Publication . Article . 2018
    Open Access English
    Authors: 
    Eisenberg-Bord, Michal; Mari, Muriel; Weill, Uri; Rosenfeld-Gur, Eden; Moldavski, Ofer; Castro, Inês G.; Soni, Krishnakant G.; Harpaz, Nofar; Levine, Tim P.; Futerman, Anthony H.; +4 more

    doi: 10.1083/jcb.201704122

    pmc: PMC5748981

    pmid: 29187527

    handle: 11370/6c8d561a-82d8-4d46-a28e-4a9218ff3a3c

    Country: Netherlands
    Project: SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), EC | MITOCHONTACTS (705853), NWO | A three-dimensional look ... (2300175771), NIH | Phospholipids in Golgi Se... (5R01GM044530-16), UKRI | Delivering accurate struc... (BB/M011801/1)

    Functional heterogeneity within the lipid droplet (LD) pool of a single cell has been observed, yet the underlying mechanisms remain enigmatic. Here, we report on identification of a specialized LD subpopulation characterized by a unique proteome and a defined geographi...

    addAdd to  ORCID orcid 
  • Other research product . Other ORP type . 2017
    Open Access English
    Authors: 
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: EC | PRONKJEWAIL (713660), NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...