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  • Open Access English
    Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian;
    Country: Netherlands
    Project: EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421), NWO | The role of autophagy in ... (2300175628), NWO | A three-dimensional look ... (2300175771)

    Autophagy is a catabolic pathway that delivers intracellular material to the mammalian lysosomes or the yeast and plant vacuoles. The final step in this process is the fusion of autophagosomes with vacuoles, which requires SNARE proteins, the homotypic vacuole fusion an...

  • Open Access English
    Gómez-Sánchez, Rubén; Rose, Jaqueline; Guimarães, Rodrigo; Mari, Muriel; Papinski, Daniel; Rieter, Ester; Geerts, Willie J; Hardenberg, Ralph; Kraft, Claudine; Ungermann, Christian; +3 more
    Country: Netherlands
    Project: NWO | The role of autophagy in ... (2300175628), NWO | A three-dimensional look ... (2300175771), EC | AutophagosomeSealing (655027), FWF | Mechanisms and hierarchy ... (P 28113), FWF | Architecture and function... (P 25522), EC | PRONKJEWAIL (713660), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    The autophagy-related (Atg) proteins play a key role in the formation of autophagosomes, the hallmark of autophagy. The function of the cluster composed by Atg2, Atg18, and transmembrane Atg9 is completely unknown despite their importance in autophagy. In this study, we...

  • Other research product . Other ORP type . 2017
    Open Access English
    Cong, Yingying; Verlhac, Pauline; Reggiori, Fulvio;
    Project: EC | PRONKJEWAIL (713660), NWO | A three-dimensional look ... (2300175771), SNSF | ER-phagy mechanisms to ma... (CRSII3_154421)

    Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes. During the past decades, it has been revealed that numero...