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152 research outcomes, page 1 of 16
  • publication . Article . Preprint . 2021
    Open Access English
    Authors:
    Tomas Mustelin; Kennedy Ukadike;
    Persistent Identifiers
    Publisher: MDPI
    Project: NIH | RESEARCH TRAINING IN RHEU... (5T32AR007108-20)

    Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. While its etiology remains elusive, current understanding suggests a multifactorial process with contributions by genetic, immunologic, hormonal, and environmental factors. A hypothesis that combi...

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  • publication . Preprint . Article . Other literature type . 2020
    Open Access English
    Authors:
    Neil K. Jairath; Mark Farha; Sudharsan Srinivasan; Ruple Jairath; Michael D. Green; Robert T. Dess; William C. Jackson; Adam B. Weiner; Edward M. Schaeffer; Shuang G. Zhao; ...
    Publisher: Preprints
    Project: NIH | A Precision Medicine Appr... (5P50CA186786-02)

    Meier estimates and Cox regression multivariable analyses. Results: Four immune clusters were identified, largely defined by plasma cell, CD4+ Memory Resting T Cells (CD4 MR), and M0 and M2 macrophage content (CD4 MRHighPlasma CellHighM0LowM2Mid, CD4 MRLowPlasma CellHig...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Maria Rubini Gimenez; P. Elliott Miller; Carlos L. Alviar; Sean van Diepen; Christopher B. Granger; Gilles Montalescot; Stephan Windecker; Lars S. Maier; Pranas Šerpytis; Rokas Serpytis; ...
    Publisher: MDPI
    Project: NIH | NRSA Training Core (5TL1TR001864-03), EC | CULPRIT-SHOCK (602202), SNSF | Addressing sex inequaliti... (P400PM_180828)

    International audience; Background: Little is known about clinical outcomes of patients with acute myocardial infraction (AMI) complicated by cardiogenic shock (CS) requiring mechanical ventilation (MV). The aim of this study was to identify the characteristics, risk fa...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Lamiaa Shalaby; Menaka Thounaojam; Amany Tawfik; Junnan Li; Khaled A. Hussein; Wan Jin Jahng; Mohamed Al-Shabrawey; Hang Fai Kwok; Manuela Bartoli; Diana Gutsaeva;
    Persistent Identifiers
    Publisher: MDPI
    Project: NIH | Uric Acid and Diabetic Re... (1R01EY028714-01A1)

    ADAM17, a disintegrin and metalloproteinase 17, is a transmembrane metalloproteinase that regulates bioavailability of multiple membrane-bound proteins via ectodomain shedding. ADAM17 activity was shown to contribute to a number of vascular pathologies, but its role in ...

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  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Ciera L Patzke; Alison Duffy; Vu H. Duong; Firas El Chaer; James A. Trovato; Maria R. Baer; Søren M. Bentzen; Ashkan Emadi;
    Persistent Identifiers
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: NIH | Protocol Specific Researc... (2P30CA134274-04)

    Currently, no standard of care exists for the treatment of relapsed or refractory acute myeloid leukemia (AML). We present our institutional experience with using either CLAG-M or HAM-pegA, a novel regimen that includes pegaspargase. This is a retrospective comparison o...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Gustavo Monteiro Viana; David Priestman; Frances M. Platt; Shaukat A. Khan; Shunji Tomatsu; Alexey V. Pshezhetsky;
    Persistent Identifiers
    Publisher: MDPI
    Project: CIHR , WT , NIH | Center for Pediatric Rese... (1P30GM114736-01)

    Mucopolysaccharidoses (MPS) are the group of lysosomal storage disorders caused by deficiencies of enzymes involved in the stepwise degradation of glycosaminoglycans. To identify brain pathology common for neurological MPS, we conducted a comprehensive analysis of brain...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Dishant K. Shah; Tyler Lynd; Donald Ho; Jun Chen; Jeremy B. Vines; Hwi-Dong Jung; Ji-Hun Kim; Ping Zhang; Hui Wu; Ho-Wook Jun; ...
    Persistent Identifiers
    Publisher: MDPI
    Project: NIH | Prohealing multifunctiona... (5R01HL125391-03)

    Dental pulp tissue exposed to mechanical trauma or cariogenic process results in root canal and/or periapical infections, and conventionally treated with root canal procedures. The more recent regenerative endodontic procedure intends to achieve effective root canal dis...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Shangyuan Ye; Hui Zhang; Fuyan Shi; Jing Guo; Suzhen Wang; Bo Zhang;
    Persistent Identifiers
    Publisher: MDPI
    Project: NIH | CORE--CLINICAL (5P30AG013854-05), NIH | The Robert H.Lurie Compre... (5P30CA060553-12)

    Background: The objective of this study was to investigate the use of ensemble methods to improve the prediction of fetal macrosomia and large for gestational age from prenatal ultrasound imaging measurements. Methods: We evaluated and compared the prediction accuracies...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Neb Duric; Mark Sak; Shaoqi Fan; Ruth M. Pfeiffer; Peter Littrup; Michael S. Simon; David H. Gorski; Haythem Y. Ali; Kristen S. Purrington; Rachel F. Brem; ...
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NIH | High-resolution, quantita... (2R44CA171601-02)

    response fashion (OR per quartile = 1.83, 95% CI: 1.32, 2.54

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Arash Kia; Prem Timsina; Himanshu Joshi; Eyal Klang; Rohit Gupta; Robert Freeman; David Reich; Max S Tomlinson; Joel T. Dudley; Roopa Kohli-Seth; ...
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NIH | MSHS Translational Scienc... (5UL1TR001433-02)

    performance to the traditional Modified Early Warning Score (MEWS) using sensitivity, specificity, and Area Under the Curve for Receiver Operating Characteristic (AUC-ROC) and Precision-Recall curves (AUC-PR). The primary outcome was escalation of care from a floor bed ...

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152 research outcomes, page 1 of 16